Factor V Leiden and the prothrombin 20210A gene mutation and osteonecrosis of the knee

Archives of Orthopaedic and Trauma Surgery

Volumn 125, Issue 1, 2005, Pages 51-55

  Björkman, Anders ^a   Burtscher, Isabella M ^a   Svensson, Peter J ^a   Hillarp, Andreas ^a   Besjakov, Jack ^a   Benoni, Göran ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Factor V Leiden; Knee; Osteonecrosis; Prothrombin gene

Indexed keywords

ALCOHOL; BLOOD CLOTTING FACTOR 5 LEIDEN; CORTICOSTEROID; PREDNISONE; PROTHROMBIN;

ADULT; AGED; ARTICLE; BLOOD CLOTTING DISORDER; BONE NECROSIS; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE MUTATION; HUMAN; KNEE DISEASE; KNEE INJURY; KNEE SURGERY; MALE; MORBIDITY; PATHOGENESIS; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN DETERMINATION; STATISTICAL SIGNIFICANCE; THROMBOSIS; VOLUNTEER;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; FACTOR V; FEMALE; HUMANS; KNEE; MALE; MIDDLE AGED; OSTEONECROSIS; POINT MUTATION; PROTHROMBIN;

EID: 14544280791     PISSN: 09368051     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00402-004-0760-8     Document Type: Article

References (29)

1. Aglietti P, Insall JN, Buzzi R, Deschamps G (1983) Idiopathic osteonecrosis of the knee. Aetiology, prognosis and treatment. J Bone Joint Surg Br 65:588-597.
2. Ahlbück S, Bauer GCH, Bohne WH (1968) Spontaneous osteonecrosis of the knee. Arthritis Rheum 11:705-733. 5700639
3. Arnoldi C, Lemperg R, Linderholm H (1975) Intraosseous hypertension and pain in the knee. J Bone Joint Surg Br 57:360-363. 1:STN:280:CSmD3crms1I%3D
4. Arruda VR, Belangero WD, Ozelo MC, Oliveira GB, Pagnano RG, Volpon JB, Annichino-Bizzacchi JM (1999) Inherited risk factors for thrombophilia among children with Legg-Calvé-Perthes disease. J Pediatr Orthop 19:84-87
5. Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, Ronde H de, Velden PA van der, Reitsma PH (1994) Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369:64-67. 10.1038/369064a0
6. Ecker ML, Lotke PA (1994) Spontaneous osteonecrosis of the knee. J Am Acad Orthop Surg 2:173-178. 10709006
7. Emmerich J, Rosendaal FR, Cattaneo M, Margaglione M, De Stefano V, Cumming T, Arruda V, Hillarp A, Reny JL (2001) Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism: pooled analysis of 8 case-control studies including 2310 cases and 3204 controls. Thromb Haemost 86:809-816. 1:CAS:528:DC%2BD3MXnsVejt7Y%3D
8. Glueck CJ, Brandt G, Gruppo R, Crawford A, Roy D, Tracy T, Stroop D, Wang P (1997) Resistance to activated protein C and Legg-Perthes disease. Clin Orthop 338:139-152. 10.1097/00003086-199705000-00021
9. Glueck CJ, Freiberg RA, Fontaine RN, Tracy T, Wang P (2001) Hypofibrinolysis, thrombophilia, osteonecrosis. Clin Orthop 386:19-33. 10.1097/00003086-200105000-00004
10. Hayek S, Kenet G, Lubetsky A, Rosenberg N, Gitel S, Wientroub S (1999) Does thrombophilia play an aetiological role in Legg-Calvé-Perthes disease? J Bone Joint Surg Br 81:686-890. 10.1302/0301-620X.81B4.9378
11. Hillarp A, Zöller B, Svensson PJ, Dahlbäck B (1997) The 20210A allele of the prothrombin gene is a common risk factor among Swedish outpatients with verified deep venous thrombosis. Thromb Haemost 78:990-992. 1:CAS:528:DyaK2sXmtVejsrk%3D
12. Hirota Y, Hotokebuchi T, Sugioka Y (1997) Idiopathic osteonecrosis of the femoral head: Nationwide epidemiologic studies in Japan. In: Urbaniak JR, Jones JP Jr (eds) Osteonecrosis: Etiology, diagnosis and treatment. American Academy of Orthopaedic Surgeons, Rosemont, pp 51-58
13. Hresko T, McDougall PA, Gorlin JB, Vamvakas EC, Kasser JR, Neufeld EJ (2002) Prospective reevaluation of the association between thrombotic diathesis and Legg-Perthes disease. J Bone Joint Surg Am 84:1613-1618
14. Jones JP Jr (1992) Intravascular coagulation and osteonecrosis. Clin Orthop 277:41-53. 1532547
15. Kirkwood BR (1988) Cohort and case-control studies. In: Kirkwood BR (ed) Essentials of medical statistics. Blackwell Scientific Publications, Oxford, pp 177-183
16. Lieberman JR, Berry DJ, Mont MA, Aaron RK, Callaghan JJ, Rayadhyaksha A, Urbaniak JR (2002) Osteonecrosis of the hip: Management in the twenty-first century. J Bone Joint Surg Am 84:834-853
17. Lotke PA (1997) Tibial osteonecrosis. In: Urbaniak JR, Jones JP Jr (eds) Osteonecrosis: Etiology, diagnosis and treatment. American Academy of Orthopaedic Surgeons, Rosemont, pp 425-428
18. Mankin HJ (1992) Nontraumatic necrosis of bone (osteonecrosis). N Engl J Med 326:1473-1479. 1:STN:280:By2B2cvjtFQ%3D
19. Mont MA, Baumgarten KM, Rifai A, Bluemke DA, Jones LC, Hungerford DS (2000) Atraumatic osteonecrosis of the knee. J Bone Joint Surg Am 82:1279-1290. 1:STN:280:DC%2BD3cvltVGgtw%3D%3D
20. Mont MA, Myers TH, Krackow KA, Hungerford DS (1997) Total knee arthroplasty for corticosteroid associated avascular necrosis of the knee. Clin Orthop 338:124-130. 9170373
21. Mont MA, Rifai A, Baumgarten KM, Sheldon M, Hungerford DS (2002) Total knee arthroplasty for osteonecrosis. J Bone Joint Surg Am 84:599-603
22. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM (1996) A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698-3703. 1:CAS:528:DyaK28XntVahsLg%3D
23. Rees DC, Cox M, Clegg JB (1995) World distribution of factor V Leiden. Lancet 346:1133-1134. 10.1016/S0140-6736(95)91803-5
24. Robertsson O, Dunbar MJ, Knutsson K, Lidgren L (2000) Past incidence and future demand for knee arthroplasty in Sweden. A report from the Swedish knee arthroplasty register regarding the effect of past and future population changes on the number of athroplasties performed. Acta Orthop Scand 71:376-380. 10.1080/000164700317393376
25. Svensson PJ, Dahlbäck B (1994) Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 330:517-522. 10.1056/ NEJM199402243300801
26. Svensson PJ, Zöller B, Mattiasson I, Dahlbäck B (1997) The factor VR506Q mutation causing APC resistance is highly prevalent amongst unselected outpatients with clinically suspected deep venous thrombosis. J Int Med 241:379-385. 10.1046/j.1365-2796.1997.124140000.x
27. Uchio Y, Ochi M, Adachi N, Nishikori T, Kawasaki K (2001) Intraosseous hypertension and venous congestion in osteonecrosis of the knee. Clin Orthop 384:217-223. 10.1097/00003086-200103000-00025
28. Yamamoto T, Bullough PG (2000) Spontaneous osteonecrosis of the knee: the result of subchondral insufficiency fracture. J. Bone Joint Surg Am 82:858-866. 10.1302/0301-620X.82B8.11194
29. Zöller B, Svensson PJ, He X, Dahlbäck B (1994) Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C. J Clin Invest 94:2521-2524