Hemoglobin H disease classification by isoelectric focusing: Molecular verification of 110 cases from Thailand

Clinical Chemistry

Volumn 51, Issue 3, 2005, Pages 641-644

  Sutcharitchan, Pranee ^a   Wang, Wen ^b   Settapiboon, Rung ^a   Amornsiriwat, Supaporn ^a   Tan, Arnold S C ^b   Chong, Samuel S ^b,c  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBULIN; HEMOGLOBIN H; TETRAMER;

ALPHA THALASSEMIA; ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; GENE DELETION; GENOTYPE; HEMOGLOBIN H DISEASE; HETEROZYGOSITY; HUMAN; ISOELECTRIC FOCUSING; PHENOTYPE; POINT MUTATION; PROTEIN ANALYSIS; THAILAND;

ALPHA-THALASSEMIA; GENOTYPE; GLOBINS; HUMANS; ISOELECTRIC FOCUSING; MUTATION; THAILAND;

EID: 14544279752     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2004.044396     Document Type: Article

References (8)

1. Weatherall DJ. The thalassemias. In: Stamatoyannopoulos G, Majerus PW, Perlmutter RM, Varmus H, eds. The molecular basis of blood diseases, Vol. 3. Philadelphia: WB Saunders, 2001:183-226.
2. Chui DH, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood 2003;101:791-800.
3. Lemmens-Zygulska M, Eigel A, Helbig B, Sanguansermsri T, Horst J, Flatz G. Prevalence of α-thalassemias in northern Thailand. Hum Genet 1996;98:345-7.
4. Fucharoen S, Winichagoon P, Pootrakul P, Piankijagum A, Wasi P. Differences between two types of Hb H disease, α-thalassemia 1/α-thalassemia 2 and α-thalassemia 1/Hb constant spring. Birth Defects Orig Artic Ser 1987;23:309-15.
5. Tan AS, Quah TC, Low PS, Chong SS. A rapid and reliable 7-deletion multiplex polymerase chain reaction assay for α-thalassemia. Blood 2001;98:250-1.
6. Waye JS, Eng B, Patterson M, Chui DH, Olivieri NF. Identification of a novel termination codon mutation (TAA→TAT, Term→Tyr) in the α2 globin gene of a Laotian girl with hemoglobin H disease. Blood 1994;83:3418-20.
7. Sanchaisuriya K, Fucharoen G, Fucharoen S. Hb Pakse [(α2) codon 142 (TAA-→TAT or Term-→Tyr)] in Thai patients with EAbart's disease and Hb H disease. Hemoglobin 2002;26:227-35.
8. Viprakasit V, Tanphaichitr V, Pung-Amritt P, Petrarat S, Suwantol L, Fisher C, et al. Clinical phenotypes and molecular characterization of Hb H-Pakse disease. Haematologica 2002;87:117-25.