Differential immune induction with subcutaneous versus oral administration of a diabetogenic insulin peptide in the NOD mouse

Annals of the New York Academy of Sciences

Volumn 1029, Issue , 2004, Pages 328-330

  Devendra, Devasenan ^a   Paronen, Johanna ^a   Liu, Edwin ^a   Moriyama, Hiroaki ^a   Miao, Dongmei ^a   Yu, Liping ^a   Eisenbarth, George S ^a  

^a UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

Diabetes; Insulin; Insulin autoantibody; NOD; Oral tolerance

Indexed keywords

FREUND ADJUVANT; INSULIN; INSULIN ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; BETA CHAIN; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; MOUSE; NONHUMAN; T LYMPHOCYTE ACTIVATION;

EID: 14544272695     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1309.039     Document Type: Conference Paper

References (3)

1. ABIRU, N., A.K. MANIATIS, L. Yu, et al. 2001. Peptide and MHC specific breaking of humoral tolerance to native insulin with the B:9-23 peptide in diabetes prone and normal mice. Diabetes 50: 1274-1281.
2. MARON, R., M. GUERAU-DE-ARELLANO, X. ZHANG & H.L. WEINER. 2001. Oral administration of insulin to neonates suppresses spontaneous and cyclophosphamide induced diabetes in the NOD mouse. J. Autoimmun. 16: 21-28.
3. BELLMANN, K., H. KOLB, B. HARTMANN, et al. 1997. Intervention in autoimmune diabetes by targeting the gut immune system. Int. J. Immunopharmacol. 19: 573-577.