Does substitution of T4 with T3 plus T4 for T4 replacement improve depressive symptoms in patients with hypothyroidism?

Annals of the New York Academy of Sciences

Volumn 1032, Issue , 2004, Pages 287-288

  Joffe, Russell T ^a   Sawka, Anna M ^b   Marriott, Michael J ^b   MacQueen, Glenda M ^b   Gernstein, Hertzl C ^b  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Depression; Thyrosine; Triiodothyronine

Indexed keywords

LEVOTHYROXINE; LIOTHYRONINE; PLACEBO; THYROID HORMONE;

ADULT; AGED; CLINICAL TRIAL; COMPREHENSIVE EPIDEMIOLOGICAL SCREEN FOR DEPRESSION; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; FEMALE; GENERAL HEALTH QUESTIONNAIRE; HORMONE SUBSTITUTION; HUMAN; HYPOTHYROIDISM; MALE; MEDICAL OUTCOME STUDY QUESTIONNAIRE; MENTAL DISEASE; MOOD; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SYMPTOM CHECKLIST 90; SYMPTOMATOLOGY; THYROID DISEASE; TREATMENT OUTCOME; WELLBEING;

EID: 14544268002     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1314.040     Document Type: Conference Paper

References (5)

1. BUNEVICIUS, R., G. KAZANAVICIUS, R, ZALINKEVICIUS, et al. 1999. Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism. N. Engl. J. Med. 340: 424-429.
2. COOKE, A.G., R.T. JOFFE & A.J. LEVITT. 1992. T3 augmentation of antidepressant treatment in T4-replaced thyroid patients. J. Clin. Psychiatry 53: 16-18.
3. GOLDBERG, D.P. & V.F. MILLIER. 1979. A scaled version of a general health questionnaire. Psychol. Med. 9: 139-145.
4. ROBERTS, R.E. & S.W. VERNON. 1983. The center for epidemiologic studies depression scale: its use in the community sample. Am. J. Psychiatry 140: 41-46.
5. DEROGATIS, L.R., R.S. LIPMAN & I. COVI. 1971. SCL-90: an outpatient psychiatric rating scale: preliminary report. Psychopharmacol. Bull. 9: 13-29.