Microbiological hydroxylation at eight individual carbon atoms of marcfortine A

Journal of Natural Products

Volumn 60, Issue 11, 1997, Pages 1139-1142

  Lee, Byung H ^a   Kornis, Gabe I ^a   Cialdella, Joyce I ^a   Clothier, Michael F ^a   Marshall, Vincent P ^a   Martin, David G ^a   McNally, Patty L ^a   Mizsak, Stephen A ^a   Whaley, Howard A ^a   Wiley, Veronica H ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE ALKALOID; MARCFORTINE A; PARAHERQUAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL METABOLISM; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG HYDROXYLATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 14444286449     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np9702805     Document Type: Article

References (18)

1. Lynn, R. C. Georgis' Parasitology for Veterinarians; W. B. Saunders Co.: Philadelphia, 1995 p 247-294.
2. Prichard, R. Vet. Parasitol. 1994, 54, 259-268.
3. Blizzard, T. A.; Mrozik, H.; Fisher, M. H.; Schaeffer, S. M. J. Org. Chem. 1990, 55, 2256-2259.
4. Blizzard, T. A.; Margiatto, G.; Mrozik, H.; Schaeffer, S. M.; Fisher, M. H. Tetrahedron Lett. 1991, 32, 2441-2444.
5. Shoop, W. L.; Egerton, J. R.; Eary, C. H.; Suhayda, D. J. Parasitol. 1990, 76, 349-351.
6. Ostlind, D. A.; Mickle, W. G.; Ewanciw, D. V.; Andriuli, F. J.; Campbell, W. C.; Hernandez, S.; Mochale, S.; Munguira, E. Res. Vet. Sci. 1990, 48, 260-261.
7. Blizzard, T. A.; Marino, G.; Sinclair, P. J.; Mrozik, H. European Pat. Appl. EP 0 354 615 A1, 1990.
8. Schaeffer, J. M.; Blizzard, T. A.; Ondeyka, J.; Goegelman, R.; Sinclair, P. J.; Mrozik, H. Biochem. Pharmacol. 1992, 43, 679-684.
9. Blizzard, T. A.; Mrozik, H. U.S. Pat. Appl. US 4, 923, 867, 1990.
10. Mrozik, H. U.S. Pat. Appl. US 4,866,060, 1989.
11. Lee, B. H.; Taylor, R. N.; Whaley, H. A.; Nelson, S. J.; Marshall, V. P. WO 9310120 A1, 1990.
12. Polonsky, J; Merrien, M. A.; Prange, T.; Pascard, C.; Moreau, S. J. Chem. Soc., Chem. Commun. 1980, 13, 601.
13. Yamazaki, M.; Okuyama, E.; Kobayashi, M.; Inoue, H. Tetrahedron Lett. 1981, 22, 135-136.
14. Archelas, A. Oxidation reactions. In Enzymatic Catalysis in Organic Synthesis; Drauz, K., Waldman, H., Eds.; VCH: Weinheim, 1995; , Vol. II, pp 667-686.
15. Lee, B. H.; Clothier, M. F. Tetrahedron Lett. 1996, 37, 6053-6056.
16. Lee, B. H.; Clothier, M. F. J. Org. Chem. 1997, 62, 1863-1867.
17. Prange, T.; Billion, M. A.; Vuilhorgne, M.; Pascard, C.; Polonsky, J. Tetrahedron Lett. 1981: 22, 1977-1980.
18. Lee, B. H. PCT Intl. Appl. WO 94/29319 A1, 1994.