Isolation from phage display libraries of lysine-deficient human epidermal growth factor variants for directional conjugation as targeting ligands

Protein Engineering

Volumn 16, Issue 12, 2003, Pages 1107-1113

  Bach, Miriam ^a   Hölig, Peter ^a   Schlosser, Eva ^a   Völkel, Tina ^a   Graser, Andreas ^a   Müller, Rolf ^b   Kontermann, Roland E ^a  

^a Vectron Therapeutics AG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

EGF receptor; Epidermal growth factor; Liposomes; Mutagenesis; Phage display; Targeting

Indexed keywords

ANTINEOPLASTIC AGENT; ARGININE; CARUBICIN; DOXORUBICIN; EPIDERMAL GROWTH FACTOR; FLUORESCEIN ISOTHIOCYANATE; GAMMA UROGASTRONE; LIGAND; LIPOSOME; LYSINE; PHTHALOCYANINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARCINOMA CELL; CONJUGATION; CONTROLLED STUDY; FLUORESCENCE; GENE MUTATION; HUMAN; HUMAN CELL; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN TARGETING; PROTEIN VARIANT;

EID: 1442359482     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/gzg145     Document Type: Article

References (32)

1. Aboud-Pirak, E., Hurwitz, E., Bellot, F., Schlessinger, J. and Sela, M. (1989) Proc. Natl Acad. Sci. USA, 86, 3778-3781.
2. Allen, T.M. (2002) Nat. Rev., 2, 750-763.
3. Baselga, J. (2001) J. Clin. Oncol., 19, S41-S44.
4. Blessing, T., Kursa, M., Holzhauser, R. Kircheis, R. and Wagner, E. (2001) Bioconjug. Chem., 12, 529-537.
5. Campion, S.R., Tadaki, D.K. and Niyogi, S.K. (1992) J. Cell. Biochem., 50, 35-42.
6. Carpenter, G. and Cohen, S. (1990) J. Biol. Chem., 265, 7709-7712.
7. Chen, P., Mrkobrada, M., Vallis, K.A., Cameron, R., Sandhu, J., Hendler, A. and Reilly, R.M. (2002) Nucl. Med. Biol., 29, 693-699.
8. Ciardiello, F. and Tortora, G. (2001) Clin. Cancer Res., 7, 2958-2970.
9. Cooke, R.M., Wilkinson, A.J., Baron, M., Pastore, A., Tappin, M.J., Campbell, I.D., Gregory, H. and Sheard, B. (1987) Nature, 327, 339-341.
10. Engler, D.A., Campion, S.R., Hauser, M.R., Cook, J.S. and Niyogi, S.K. (1992) J. Biol. Chem., 267, 2274-2281.
11. Forssen, E. and Willis, M. (1998) Adv. Drug Deliv. Rev., 29, 249-271.
12. Jinno, H., Ueda, M., Ozawa, S., Kikuchi, K., Ikeda, T., Enomoto, K. and Kitajima, M. (1996) Cancer Chemother. Pharmacol., 38, 303-308.
13. Kikuchi, A., Sugaya, S., Ueda, H., Tanaka, K., Aramaki, Y., Hara, T., Arima, H., Tsuchiya, S. and Fuwa, T. (1996) Biochem. Biophys. Res. Commun., 227, 666-671.
14. Koivunen, E., Wang, B. and Ruoaslahti, E. (1995) Biotechnology, 13, 265-270.
15. Kontermann, R.E. (2001) In Kontermann, R.E. and Dübel, S. (eds), Antibody Engineering. Springer, Heidelberg, pp. 137-148.
16. Kontermann, R.E., Martineau, P., Cummings, C.E., Karpas, A., Allen, D., Derbyshire, E. and Winter, G. (1997) Immunotechnology, 3, 137-144.
17. Kullberg, B.E., Bergstrand, N., Carsson, J., Edwards, K., Johnsson, M., Sjoberg, S. and Gedda, L. (2002) Bioconjug. Chem., 13, 737-743.
18. Kullberg, E.B., Nestor, M. and Gedda, L. (2003) Pharm. Res., 20, 229-236.
19. Lee, C.H., Lee, E.C., Tsai, S.T., Kung, H.J., Liu, Y.C. and Hwang, J. (1993) Protein Eng., 6, 433-440.
20. Lemmon, M.A., Bu, Z., Ladbury, J.E., Zhou, M., Pinchasi, D., Lax, I., Engelman, D.M. and Schlessinger, J. (1997) EMBO J., 16, 281-294.
21. Lutsenko, S.V., Feldman, N.B., Finakova, G.V., Posypanova, G.A., Severin, S.E., Skryabin, K.G., Kirpichnikov, M.P., Lukyanets, E.A. and Vorozhtsov, G.N. (1999) Tumor Biol., 20, 218-224.
22. Lutsenko, S.V., Feldman, N.B., Finakova, G.V., Gukasova, N.V., Petukhov, S.P., Posypanova, G.A., Skryabin, K.G. and Severin, S.E. (2000) Tumor Biol., 21, 367-374.
23. Lutsenko, S.V., Feldman, N.B. and Severin, S.E. (2002) J. Drug Target, 10, 567-571.
24. Marty, C., Odermatt, B., Schott, H., Neri, D., Ballmer-Hofer, K., Klemenz, R. and Schwendener, R.A. (2002) Br. J. Cancer, 87, 106-112.
25. Nicholson, R.I., Gee, J.M.W. and Harper, M.E. (2001) Eur. J. Cancer, 37, S9-S15.
26. Nielsen, U.B., Kirpotin, D.B., Pickering, E.M., Hong, K., Park, J.W., Shalaby, M.R., Shao, Y., Benz, C.C. and Marks, J.D. (2002) Biochim. Biophys. Acta, 1591, 109-118.
27. Park, J.W. et al. (2002) Clin. Cancer Res., 8, 1172-1181.
28. Salomon, D.S., Bradt, R., Ciardiello, F. and Normanno, N. (1995) Crit. Rev. Oncol. Hematol., 19, 183-232.
29. Schmidt, M., Vakalopoulou, E., Schneider, D.W. and Wels, W. (1997) Br. J. Cancer, 75, 1575-1584.
30. Souriau, C., Fort, P., Roux, P., Hartley, O., Lefranc, M.-P. and Weill, M. (1997) Nucleic Acids Res., 25, 1585-1590.
31. Watkins, S.J., Mesyanzhinov, V.V., Kurochkina, L.P. and Hawkins, R.E. (1997) Gene Ther., 4, 1004-1012.
32. Yamamoto, Y. et al. (2003) Nat. Biotechnol., 21, 546-551.