Insulin Resistance, Obesity, and the Risk of Neurodegenerative Diseases

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 59, Issue 2, 2004, Pages 189-

  Vellas, Bruno ^a,c   Sinclair, Alan ^b  

^a TOULOUSE UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c Toulouse University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; CHAPERONE;

ALZHEIMER DISEASE; BODY MASS; CALORIC INTAKE; COGNITION; DEGENERATIVE DISEASE; DEMENTIA; DISEASE ASSOCIATION; HUMAN; INSULIN RESISTANCE; MOOD DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; NOTE; OBESITY; PRIORITY JOURNAL;

EID: 1442355677     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (8)

1. Gustafson D, Rothenberg E, Blennow K, Steen B, Skoog I. An 18-year follow-up of overweight and risk of Alzheimer disease. Arch Intern Med. 2003;163:1524-1528.
2. Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL. Overweight and obesity in the United Sates: prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord. 1998;22:39-47.
3. Peila R, Rodriguez BL, Launer LJ. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies. The Honolulu-Asia Aging study. Diabetes. 2002;51:1256-1262.
4. Charoonruk G, Munger RG, Wengreen H, et al. Diabetes mellitus and cognitive decline among elderly residents of Cache County, Utah. J Nutr Health Aging. 2003;7:203.
5. Watson GS, Peskind ER, Asthana S, et al. Insulin increases CSF A beta 42 levels in normal older adults. Neurology. 2003;60:1899-1903.
6. Rasgon N, Jarvik L. Insulin resistance, affective disorders, and Alzheimer's disease: review and hypothesis. J Gerontology Med Sci. 2004;59A: 178-183.
7. Elias PK, Elias MF, D'Agostino RB, et al. NIDDM and blood pressure as risk factors for poor cognitive functioning. The Framingham Study. Diabetes Care. 1997;20:1388-1395.
8. Mattson P. Will caloric restriction and folate protect against AD and PD? Neurology. 2003;60:690-695.