Synthesis and Evaluation of A Hematoporphyrin Derivative in A Folate Receptor-targeted Solid-Lipid Nanoparticle Formulation

Anticancer Research

Volumn 24, Issue 1, 2004, Pages 161-165

  Stevens, Phillip J ^a   Sekido, Masaru ^a   Lee, Robert J ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b College of Pharmacy ^*  (United States)

Author keywords

Folate receptor; Hematoporphyrin; Photodynamic therapy; Targeted solid lipid nanoparticle

Indexed keywords

ALCOHOL; FOLATE POLYETHYLENE GLYCOL CHOLESTEROL; FOLIC ACID; HEMATOPORPHYRIN DERIVATIVE; MACROGOL; NANOPARTICLE; OCTADECYLAMINE; PHOSPHATIDYLCHOLINE; POLYETHYLENE GLYCOL DISTEAROYLPHOSPHATIDYLETHANOLAMINE; SOLID LIPID NANOPARTICLE; TRIOLEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LIPOPHILICITY; PARTICLE SIZE; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

AMINES; CARRIER PROTEINS; DRUG SCREENING ASSAYS, ANTITUMOR; HEMATOPORPHYRINS; HUMANS; KB CELLS; LIPIDS; LIPOSOMES; MICROSCOPY, FLUORESCENCE; NANOTECHNOLOGY; PARTICLE SIZE; PHOTOSENSITIZING AGENTS; RECEPTORS, CELL SURFACE;

EID: 1442350542     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Konan NY, Gurny R and Allemann E: State of the art in the delivery of photosensitizers for photodynamic therapy. J Photochem Photobiol B 66: 89-106, 2002.
2. Renno RZ and Miller JW: Photosensitizer delivery for photodynamic therapy of choroidal neovascularization. Adv Drug Deliv Rev 52: 63-78, 2001.
3. Ricchelli F: Photophysical properties of porphyrins in biological membranes. J Photochem Photobiol B 29: 109-118, 1995.
4. Girotti AW: Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects and cytoprotective mechanisms. J Photochem Photobiol B 63: 103-113, 2001.
5. Osterloh J and Vicente MGH: Mechanisms of porphyrinoid localization in tumors. J Porphyrins and Phthalocyanines 6: 305-324, 2002.
6. Hasan T, Moor AcE and Ortel B: Photodynamic therapy of cancer. Cancer Medicine 5: 489-502, 2000.
7. Stevens PJ and Lee RJ: A folate receptor-targeted emulsion formulation for paclitaxel. Anticancer Res 23 (6): 4927-4932, 2003.
8. Kongshaug M, Moan J, Cheng LS, Garbo GM, Kolboe S, Morgan AR and Rimington C: Binding of drugs to human plasma proteins, exemplified by Sn(IV)-etiopurpurin dichloride delivered in chremophore and DMSO. Int J Biochem 25(5): 739-760, 1993.
9. Kongshaug M, Cheng LS, Moan J and Morgan AR: Binding of etiopurpurin and tin-coordinated etiopurpurin to human plasma proteins. Delivery in cremophore EL and dimethylsulfoxide (Paper II). Int J Biochem Cell Biol 27(1): 71-87, 1995.
10. Galantai R, Bardos-Nagy, Modos K, Kardo, J, Zavadszky P and Fidy J: Serum albumin-lipid membrane interaction influencing the uptake of porphyrins. Arch Biochem Biophys 373(1): 261-270, 2000.
11. Sudimack J and Lee RJ: Targeted drug delivery via the folate receptor. Adv Drug Delivery Rev 41: 147-162, 2000.
12. Weitman SD, Lark RH, Coney LR, Fort DW, Frasca V, Zurawski Jr VR and Kamen BA: Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues. Cancer Res 52(12): 3396-3401, 1992.
13. Weitman SD, Weinberg AG, Coney LR, Zurawski VR, Jennings DS and Kamen BA: Cellular localization of the folate receptor: potential role in drug toxicity and folate homeostasis. Cancer Res 52: 6708-6711, 1992.
14. Garin-Chesa P, Campbell I, Saigo PE, Lewis Jr JL, Old LJ and Rettig WJ: Trophoblast and ovarian cancer antigen LK26. Am J Pathol 142(2): 557-567, 1993.
15. Toffoli G, Cernigoi C, Russo A, Gallo A, Bagnoli M and Boiocchi M: Overexpression of folate binding protein in ovarian cancers. Int J Cancer 74: 193-198, 1997.
16. Lee RJ, Wang S and Low PS: Measurement of endosome pH following folate receptor-mediated endocytosis. Biochim Biophys Acta-Biomembr 1312: 237-242, 1996.
17. Lee RJ and Low PS: Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro. Biochim Biophys Acta-Biomembr 1233: 134-144, 1995.
18. Lee RJ and Low PS: Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis. J Biol Chem 269(5): 3198-3204, 1994.
19. Leamon CP and Low PS: Cytotoxicity of momordin-folate conjugates in cultured human cells. J Biol Chem 267(35): 24966-24971, 1992.
20. Leamon CP, Pastan I and Low PS: Cytotoxicity of folate-pseudomonas exotoxin conjugates toward tumor cells. J Biol Chem 368(33): 24827-24854, 1993.
21. Leamon CP and Low PS: Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc Natl Acad Sci USA 88: 5572-5576, 1991.
22. Turek JJ, Leamon CP and Low PS: Endocytosis of folate-protein conjugates: ultrastructural localization in KB cells. J Cell Sci 106: 423-430, 1993.
23. Rothberg KG, Ying YS, Kolhouse JF, Kamen BA and Anderson RG: The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway. J Cell Biol 110: 637-649, 1990.
24. Kamen BA and Capdevila A: Receptor-mediated folate accumulation is regulated by the cellular folate content. Proc Natl Acad Sci USA 83: 5983-5987, 1986.
25. Gosselin MA and Lee RJ: Folate receptor-targeted liposomes as vectors for therapeutic agents. Biotechnol Ann Rev 8: 103-131, 2002.
26. Guo W, Sudimack J and Lee RJ: Receptor-specific delivery of liposomes via folate-PEG-chol. J Liposome Res 10: 179-195, 2000.