Effect of Zinc Salts on Respiratory Syncytial Virus Replication

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 3, 2004, Pages 783-790

  Suara, Rahaman O ^a   Crowe Jr , James E ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; MAGNESIUM; MANGANESE; ZINC DERIVATIVE;

ARTICLE; CONCENTRATION RESPONSE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS CULTURE; VIRUS INHIBITION; VIRUS REPLICATION;

ADSORPTION; CELL LINE; CELL SURVIVAL; HUMANS; PLAQUE ASSAY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VIRUS REPLICATION; ZINC;

EID: 1442349190     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.3.783-790.2004     Document Type: Article

References (28)

1. Arens, M., and S. Travis. 2000. Zinc salts inactivate clinical isolates of herpes simplex virus in vitro. J. Clin. Microbiol. 38:1758-1762.
2. Beck, F. W. J., A. S. Prasad, J. Kaplan, J. T. Fitzgerald, and G. J. Brewe. 1997. Changes in cytokine production and T cell subpopulations in experimentally induced zinc-deficient humans. Am. J. Physiol. 272:E1002-E1007.
3. Bhutta, Z. A., R. E. Black, K. H. Brown, J. M. Gardner, S. Gore, et al. 1999. Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized control clinical trials. J. Pediatr. 135:689-697.
4. Castillo-Duran, C., G. Heresi, M. Fisberg, and R. Uauy. 1987. Controlled trial of zinc supplementation during recovery from malnutrition: effects on growth and immune function. Am. J. Clin. Nutr. 45:602-608.
5. Eby, G. A., D. R. Davis, and W. W. Halcomb. 1984. Reduction in duration of common cold by zinc gluconate lozenges in a double-blind study. Antimicrob. Agents Chemother. 25:20-24.
6. Fisher, R. G., W. C. Gruber, K. M. Edwards, G. W. Reed, S. J. Tollefson, J. M. Thompson, and P. F. Wright. 1997. Twenty years of outpatient respiratory syncytial virus infection: a framework for vaccine efficacy trials. Pediatrics 99:7-16.
7. Geist, F. C., J. A. Bateman, and F. G. Hayden. 1987. In vitro activity of zinc salts against human rhinovirus. Antimicrob. Agents Chemother. 31:622-624.
8. Glezen, W. P., A. Peredes, J. E. Allison, L. H. Taber, and A. L. Frank. 1981. Risk of respiratory syncytial virus infection for infants from low-income families in relation to age sex, ethnic group, and maternal antibody level. J. Pediatr. 98:708-715.
9. Glezen, W. P., A. Peredes, J. E. Allison, L. H. Taber, and J. A. Kasel. 1986. Risk of primary infection and reinfection with respiratory syncytial virus. Am. J. Dis. Child. 40:543-546.
10. Haraguchi, Y., H. Sakurai, S. Hussain, B. M. Anner, and H. Hoshino. 1999. Inhibition of HIV-1 infection by zinc group metal compounds. Antivir. Res. 43:123-133.
11. Katz, E., and E. Margalith. 1981. Inhibition of vaccinia virus maturation by zinc chloride. Antimicrob. Agents Chemother. 19:213-217.
12. Keen, C. L., and M. E. Gershwin. 1990. Zinc deficiency and immune function. Annu. Rev. Nutr. 10:415-431.
13. Korant, B. D., and B. E. Butterworth. 1976. Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides. J. Virol. 18: 298-306.
14. Korant, B. D., J. C. Kauer, and B. E. Butterworth. 1974. Zinc ions inhibit replication of rhinoviruses. Nature (London) 248:588-590.
15. Kumel, G., S., Schrader, H. Zentgraf, H. Daus, and M. Brendel. 1990. The mechanism of antiherpetic activity of zinc sulphate. J. Gen. Virol. 71:2989-2997.
16. Meshitsuka, S., M. Ishizawa, and T. Nose. 1987. Uptake and toxic effects of heavy metal ions: interactions among cadmium, copper and zinc in cultured cells. Experientia. 43:151-156.
17. Mossad, S. B., M. L. Macknin, S. V. Medendorp, and P. Mason. 1996. Zinc gluconate lozenges for treating the common cold: a randomized, double blind, placebo-controlled study. Ann. Intern. Med. 125:81-88.
18. Mulholland, E. K., O. O. Ogunlesi, R. A. Adegbola, M. Weber, B. E. Sam, A. Palmer, M. J. A. Manary, O. Secka, M. Aidoo, D. Hazlett, H. Whittle, and B. M. Greenwood. 1999. Etiology of serious infections in young Gambian infants. Pediatr. Infect. Dis. J. 18(10 Suppl.):S35-S41.
19. Prasad, A. S., J. T. Fitzgerald, B. Bao, F. W. J. Beck, and H. Chandrasekar. 2000. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. Ann. Intern. Med. 133:245-252.
20. Sazawal, S., R. E. Black, S. Jalla, S. Mazumdar, A. Sinha, and M. K. Bhan. 1998. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double blind controlled trial. Pediatrics 102:1-5.
21. Shankar, A. H., and A. S. Prasad. 1998. Zinc and immune function: the biological basis of altered resistance to infection. Am. J. Clin. Nutr. 68(2 Suppl.):447S-463S.
22. Smith, D. S., E. C. Helzner, C. E. Nuttall, Jr., M. Collins, R. A. Rofman, D. Ginsberg, C. B. Goswick, and A. Magner. 1989. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob. Agents Chemother. 33:646-648.
23. Suara, R. O., and W. P. Glezen. 1995. Contribution of respiratory viruses to the worldwide problem of pneumonia in young children. Semin. Pediatr. Infect. Dis. 6:121-127.
24. Sugarma, B. 1983. Zinc and infection. Rev. Infect. Dis. 5:137-147.
25. Victoria, C. G., B. R. Kirkwood, A. Ashworth, R. E. Black, S. Rogers, S. Sazawal, H. Campbell, and S. Gove. 1999. Potential interventions for the prevention of childhood pneumonia in developing countries: improving nutrition. Am. J. Clin. Nutr. 70:309-320.
26. Wahba, A. 1980. Topical application of micro zinc-solutions: a new treatment for herpes simplex infections of the skin? Acta Dermatol. Venerol. (Stockholm) 60:175-177.
27. Weber, M. W., K. Mulholland, and B. M. Greenwood. 1998. Respiratory syncytial virus infection in tropical and developing countries. Trop. Med. Int. Health 125:268-280.
28. Weisman, K., J. P. Jokobsen, J. E. Weissman, U. M. Hammer, S. M. Nyholm, B. Hansen, K. E. Lomholt, and K. Schmidt. 1990. Zinc gluconate lozenges for common cold: a double blind clinical trial. Dan. Med. Bull. 37:279-291.