Autosomal Trisomy and Maternal Use of Multivitamin Supplements

American Journal of Medical Genetics

Volumn 125 A, Issue 2, 2004, Pages 113-116

  Botto, Lorenzo D ^a   Mulinare, Joseph ^a   Yang, Quanhe ^a   Liu, Yecai ^a   Erickson, J David ^a  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Chromosomal; Congenital abnormality; Down syndrome; Folic acid; Pregnancy; Prevention; Trisomy; Vitamins

Indexed keywords

FOLIC ACID; MULTIVITAMIN;

ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; HUMAN; MAJOR CLINICAL STUDY; MATERNAL NUTRITION; PREVALENCE; PRIORITY JOURNAL; RISK REDUCTION; TREATMENT FAILURE; TRISOMY 13; TRISOMY 18; VITAMIN SUPPLEMENTATION;

EID: 1442332974     PISSN: 15524825     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajmg.a.20436     Document Type: Article

References (14)

1. Botto LD, Yang Q. 2000. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review. Am J Epidemiol 151:862-877.
2. Chadefaux-Vekemans B, Coude M, Muller F, Oury JF, Chabli A, Jais JP, Kamoun P. 2002. Methylenetetrahydrofolate reductase polymorphism in the etiology of Down syndrome. Pediatr Res 51:766-767.
3. Collins JS, Olson RL, DuPont BR, Wolff DJ, Best RG, Stevenson RE. 2002. Prevalence of aneuploidies in South Carolina in the 1990s. Genet Med 4:131-135.
4. Erickson JD, Mulinare J, McClain PW. 1984. Vietnam veterans' risk for fathering babies with birth defects. Atlanta: Centers for Disease Control.
5. Hassold T, Hunt P. 2001. To err (meiotically) is human: The genesis of human aneuploidy. Nat Rev Genet 2:280-291.
6. Hassold TJ, Burrage LC, Chan ER, Judis LM, Schwartz S, James SJ, Jacobs PA, Thomas NS. 2001. Maternal folate polymorphisms and the etiology of human nondisjunction. Am J Hum Genet 69:434-439.
7. Hobbs CA, Sherman SL, Yi P, Hopkins SE, Torfs CP, Hine RJ, Pogribna M, Rozen R, James SJ. 2000. Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome. Am J Hum Genet 67:623-630.
8. James SJ, Pogribna M, Pogribny IP, Melnyk S, Hine RJ, Gibson JB, Yi P, Tafoya DL, Swenson DH, Wilson VL, Gaylor DW. 1999. Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome. Am J Clin Nutr 70:495-501.
9. March of Dimes. 2000. What is Down syndrome? http://www.modimes.org/HealthLibrary/334_602.htm
10. Mulinare J, Cordero JF, Erickson JD, Berry R.J. 1988. Periconceptional use of multivitamins and the occurrence of neural tube defects. JAMA 260:3141-3145.
11. O'Leary VB, Parle-McDermott A, Molloy AM, Kirke PN, Johnson Z, Conley M, Scott JM, Mills JL. 2002. MTRR and MTHFR polymorphism: Link to Down syndrome? Am J Med Genet 107:151-155.
12. Petersen MB, Grigoriadou M, Mikkelsen M. 2000. A common mutation in the methylenetetrahydrofolate reductase is not a risk factor for Down syndrome. Am J Hum Genet 67:141.
13. Ray JC, Meier C, Vermeulen MJ, Cole DE, Wyatt PR. 2003. Prevalence of trisomy 21 following folic acid food fortification. Am J Med Genet 120A:309-313.
14. Stuppia L, Gatta V, Gaspari AR, Antonucci I, Morizio E, Calabrese G, Palka G. 2002. C677T mutation in the 5,10-MTHFR gene and risk of Down syndrome in Italy. Eur J Hum Genet 10:388-390.