Estimating blood-brain barrier opening in a rat model of hemorrhagic transformation with Patlak plots of Gd-DTPA contrast-enhanced MRI

Acta Neurochirurgica, Supplementum

Volumn , Issue 86, 2003, Pages 35-37

  Fenstermacher, J D ^a   Knight, R A ^b,c   Ewing, J R ^b,c   Nagaraja, T ^a   Nagesh, V ^b   Yee, J S ^b   Arniego, P A ^b  

^a HENRY FORD HEALTH SCIENCES CENTER   (United States)

^b HENRY FORD HOSPITAL   (United States)

^c OAKLAND UNIVERSITY   (United States)

Author keywords

Blood brain barrier; Cerebral edema; Gd DTPA imaging; Hemorrhagic transformation; Magnetic resonance imaging; Quantitative autoradiography; Water distribution

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; GADOLINIUM PENTETATE;

ANIMAL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN HEMORRHAGE; IMAGE ENHANCEMENT; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; RAT; WISTAR RAT;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CEREBRAL HEMORRHAGE; CONTRAST MEDIA; GADOLINIUM DTPA; IMAGE ENHANCEMENT; MAGNETIC RESONANCE IMAGING; MALE; RATS; RATS, WISTAR;

EID: 1442328324     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0651-8_7     Document Type: Article

References (4)

1. Bereczki D, Wei L, Otsuka T, Hans F-J, Acuff V, Patlak C, Fenstermacher J (1993) Hypercapnia slightly raises blood volume and sizably elevates flow velocity in brain microvessels. Am J Physiol 264: H1360-H1369
2. Blasberg RG, Fenstermacher JD, Patlak CS (1983) The transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes. J Cereb Blood Flow Metab 3: 8-32
3. Patlak CS, Blasberg RG, Fenstermacher JD (1983) Graphical evaluation of blood-to-brain transfer constants from multiple- time uptake data. J Cereb Blood Flow Metab 3: 1-7
4. Patlak CS, Fenstermacher JD (1975) Measurements of blood- brain transfer constants by ventriculocisternal perfusion. Am J Physiol 229: 877-874