Arrhythmia in Isolated Prenatal Hearts after Ablation of the Ca v 2.3 (α1E) Subunit of Voltage-gated Ca 2+ Channels

Cellular Physiology and Biochemistry

Volumn 14, Issue 1-2, 2004, Pages 11-22

  Lu, Zhong Ju ^b   Pereverzev, Alexey ^a   Liu, Hui Lin ^b   Weiergräber, Marco ^a   Henry, Margit ^a   Krieger, Andreas ^a   Smyth, Neil ^a   Hescheler, Jürgen ^a   Schneider, Toni ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Cardiac development; e c coupling; E type Ca channel; R type Ca channel; SNX 482

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL R TYPE; CALCIUM CHANNEL T TYPE; CALCIUM ION; DIHYDROPYRIDINE; OMEGA CONOTOXIN; SNX 482; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRODE; EMBRYO; EMBRYO (ANATOMY); FEMALE; HEART ARRHYTHMIA; HEART BEAT; ISOLATED HEART; MOUSE; NONHUMAN; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; WILD TYPE;

ANIMALIA; MURINAE;

EID: 1442327923     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076922     Document Type: Article

References (53)

1. Wilson SM, Toth PT, Oh SB, Gillard SE, Volsen S, Ren D, Philipson LH, Lee EC, Fletcher CF, Tessarollo L, Copeland NG, Jenkins NA and Miller RJ: The Status of Voltage-Dependent Calcium Channels in alpha1E Knock-Out Mice. J Neurosci 2000;20:8566-8571.
2. 2+ channel. Proc Natl Acad Sci USA 2000;97:6132-6137.
3. Kubota M, Murakoshi T, Saegusa H, Kazuno A, Zong S, Hu Q, Noda T and Tanabe T: Intact LTP and Fear Memory but Impaired Spatial Memory in Mice Lacking Cav2.3 (α1E) Channel. Biochem Biophys Res Commun 2001;282:242-248.
4. 2+ channel in ischemic neuronal injury. Neuroreport 2002;13:261-265.
5. Lee SC, Choi S, Lee T, Kim HL, Chin H and Shin HS: Molecular basis of R-type calcium channels in central amygdala neurons of the mouse. Proc Natl Acad Sci USA 2002;99:3276-3281.
6. Sochivko D, Pereverzev A, Smyth N, Gissel C, Schneider T and Beck H: The α1E calcium channel subunit underlies R-type calcium current in hippocampal and cortical pyramidal neurons. J Physiol 2002;542:699-710.
7. v 2.3 (α1E) Calcium Channel Exhibit Hyperglycemia. Biochem Biophys Res Commun 2001;289:791-795.
8. 2+ channel. Biochem Biophys Res Commun 2001;288:1032-1036.
9. 2+ channels. Mol Endocrinol 2002;16:884-895.
10. Nilius B: T-type calcium channels in myocardial cells. In Tsien RW, Clozel JP and Nargeot J. eds: Low-Voltage-Activated T-type Calcium Channels, Adis International Limited, Tattenhall, 1998, p. 16-28.
11. 2+ release from the sarcoplasmic reticulum in guinea-pig ventricular myocytes. J Physiol (Lond) 1998;508.2:439-451.
12. Fabiato AE and Fabiato F: Calcium and cardiac excitation-contraction coupling. Annu Rev Physiol 1979;41:473-484.
13. 2+ channels. Cell 2000;102:89-97.
14. Ferry DR, Goll A and Glossmann H: Photoaffinity labelling of the cardiac calcium channel. (-)-[3H] azidopine labels a 165 kDa polypeptide, and evidence against a [3H]-1,4-dihydropyridine-isothiocyanate being a calcium-channel - specific affinity ligand. Biochem J 1987;243:127-135.
15. Schneider T and Hofmann F: The bovine cardiac receptor for calcium channel blockers is a 195-kDa protein. Eur J Biochem 1988;174:369-375.
16. Haase H, Striessnig J, Holtzhauer M, Vetter R and Glossmann H: A rapid procedure for the purification of cardiac 1,4- dihydropyridine receptors from porcine heart. Eur J Pharmacol 1991;207:51-59.
17. Seisenberger C, Specht V, Welling A, Platzer J, Pfeifer A, Kuhbandner S, Striessnig J, Klugbauer N, Feil R and Hofmann F: Functional embryonic cardiomyocytes after disruption of the L-type alpha 1C (Cav1.2) calcium channel gene in the mouse. J Biol Chem 2000;275:39193-39199.
18. Xu M, Welling A, Paparisto S, Hofmann F and Klugbauer N: Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice. J Biol Chem 2003;278:40837-40841.
19. Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M and Lee J-H: Molecular characterization of a neuronal low voltage-activated T-type calcium channel. Nature 1998;391:896-900.
20. Cribbs LL, Lee J-H, Yang J, Satin J, Zhang Y, Daud A, Barclay J, Williamson MP, Fox M, Rees M and Perez-Reyes E: Cloning and characterization of α1H from human heart, a member of the T-type calcium channel gene family. Circ Res 1998;83:103-109.
21. Piedras-Renteria ES, Chen CC and Best PM: Antisense oligonucleotides against rat brain alpha1E DNA and its atrial homologue decrease T-type calcium current in atrial myocytes. Proc Natl Acad Sci USA 1997;94:14936-14941.
22. Randall AD and Tsien RW: Contrasting biophysical and pharmacological properties of T-type and R-type calcium channels. Neuropharmacology 1997;36:879-893.
23. 2+ currents. Neuropharmacology 1998;37:957-972.
24. Mitchell JW, Larsen JK and Best PM: Sequence of E-type calcium channel gene isoforms from atrial myocytes and the cellular distribution of their protein products. Biophys J 1999;76:A91.
25. 2+ channel in chromogranin-positive muscle cells of rat heart, and in distal tubules of human kidney. J Histochem Cytochem 2000;48:807-819.
26. Egert U, Knott T, Schwarz C, Nawrot M, Brandt A, Rotter S and Diesmann M: MEA-Tools: an open source toolbox for the analysis of multi-electrode data with MATLAB. J Neurosci Methods 2002;117:33-42.
27. Banach K, Halbach MD, Hu P, Hescheler J and Egert U: Development of electrical activity in cardiac myocyte aggregates derived from mouse embryonic stem cells. Am J Physiol Heart Circ Physiol 2003;284:H2114-H2123.
28. Wang HS and Cohen IS: Calcium channel heterogeneity in canine left ventricular myocytes. J Physiol 2003;547:825-833.
29. 2+ Channel α1 Subunits in Cell Lines and Tissues. Eur J Biochem 1998;257:274-285.
30. Spach MS, Barr RC, Serwer GA, Kootsey JM and Johnson EA: Extracellular potentials related to intracellular action potentials in the dog Purkinje system. Circ Res 1972;30:505-519.
31. Halbach, M. D., Egert, U., Hescheler, J., and Banach, K. Estimation of Action Potential Changes from Field Potential Recordings in Multicellular Mouse Cardiac Myocyte Cultures. Cellular Physiology and Biochemistry 13, 271-284. 2003.
32. Mehrke G, Pereverzev A, Grabsch H, Hescheler J and Schneider T: Receptor Mediated Modulation of Recombinant Neuronal Class E Calcium Channels. FEBS Lett 1997;408:261-270.
33. Mitchell JW, Larsen JK and Best PM: Identification of the calcium channel alpha 1E (Ca(v)2.3) isoform expressed in atrial myocytes. Biochim Biophys Acta 2002;1577:17-26.
34. 2+ Channels: Electrophysiological Characterization of Isoforms. Mol Cell Neurosci 2002;21:352-365.
35. 2+ channel activity depends on an arginine rich region in the cytosolic II-III loop. Eur J Neurosci 2003;18:841-855.
36. Newcomb R, Szoke B, Palma A, Wang G, Chen XH, Hopkins W, Cong R, Miller J, Urge L, Tarczy-Hornoch K, Loo JA, Dooley DJ, Nadasdi L, Tsien RW, Lemos J and Miljanich G: Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas. Biochemistry 1998;37:15353-15362.
37. v 2.3) Calcium Channels. Biophys J 2001;81:79-88.
38. Aggarwal R, Shorofsky SR, Goldman L and Balke CW: Tetrodotoxin-blockable calcium currents in rat ventricular myocytes; a third type of cardiac cell sodium current. J Physiol 1997;505:353-369.
39. Sha Q, Robinson SW, McCulle SL, Shorofsky SR, Welling PA, Goldman L and Balke CW: An antisense oligonucleotide against H1 inhibits the classical sodium current but not ICa(TTX) in rat ventricular cells. J Physiol 2003;547:435-440.
40. Stephens GJ, Page KM, Burley JR, Berrow NS and Dolphin AC: Functional expression of rat brain cloned alpha1E calcium channels in COS-7 cells. Pflugers Arch 1997;433:523-532.
41. Leuranguer V, Monteil A, Bourinet E, Dayanithi G and Nargeot J: T-type calcium currents in rat cardiomyocytes during postnatal development: contribution to hormone secretion. Am J Physiol Heart Circ Physiol 2000;279:H2540-H2548.
42. Reuter H: The dependence of slow inward current in Purkinje fibres on the extracellular calcium-concentration. J Physiol 1967;192:479-492.
43. Trautwein W, Kameyama M, Hescheler J and Hofmann F: Cardiac calcium channels and their transmitter modulation. Prog Zool 1986;33:163-182.
44. 1D subunit antibody in rat dorsal root ganglion neurones and guinea-pig myocytes. J Physiol (Lond ) 1997;502:307-319.
45. 2+ channels of the embryonic mouse heart. Eur J Pharmacol 2002;447:279-284.
46. 2+ Channel α1E Subunit. Eur J Neurosci 1998;10:916-925.
47. 2+ channel isoforms in cerebellum, INS-1 cells, and neuroendocrine cells of the digestive system. J Histochem Cytochem 1999;47:981-993.
48. Schneider T, Wei X, Olcese R, Costantin JL, Neely A, Palade P, Perez-Reyes E, Qin N, Zhou J, Crawford GD, Smith RG, Appel SH, Stefani E and Birnbaumer L: Molecular analysis and functional expression of the human type E α1 subunit. Receptors & Channels 1994;2:255-270.
49. Shorofsky SR and Balke CW: Calcium currents and arrhythmias: insights from molecular biology. Am J Med 2001;110:127-140.
50. Chen-Izu Y, Sha Q, Shorofsky SR, Robinson SW, Wier WG, Goldman L and Balke CW: I(Ca(TTX)) channels are distinct from those generating the classical cardiac Na(+) current. Biophys J 2001;81:2647-2659.
51. Soong TW, Stea A, Hodson CD, Dubel SJ, Vincent SR and Snutch TP: Structure and functional expression of a member of the low voltage-activated calcium channel family. Science 1993;260:1133-1136.
52. 1E calcium channel subtypes. J Biol Chem 1994;269:22347-22357.
53. Niidome T, Kim M-S, Friedrich T and Mori Y: Molecular cloning and characterization of a novel calcium channel from rabbit brain. FEBS Lett 1992;308:7-13.