Transitional Increase in Growth Fraction Estimated by Ki-67 Index after Irradiation to Human Tumor in Xenograft

Anticancer Research

Volumn 24, Issue 1, 2004, Pages 107-110

  Takahashi, Takeo ^a   Nakano, Takashi ^b   Oka, Kuniyuki ^c   Ando, Koichi ^d  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c MITO SAISEIKAI GENERAL HOSPITAL   (Japan)

^d NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Growth fraction; Human tumor; Ki 67; Radiation; Recruitment

Indexed keywords

KI 67 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER RADIOTHERAPY; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL FUNCTION; CELL KINETICS; CONTROLLED STUDY; DNA DETERMINATION; FLOW CYTOMETRY; GROWTH STIMULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MEASUREMENT; MOUSE; NONHUMAN; NUDE MOUSE; PARAMETER; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RELIABILITY; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FLOW CYTOMETRY; G1 PHASE; HUMANS; KI-67 ANTIGEN; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; SALIVARY GLAND NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS;

EID: 1442326143     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Gerdes J, Schwab U, Lemke H and Stein H: Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31: 13-20, 1983.
2. Gerdes J, Lemke H, Baisch H, Wacker H, Schwab U and Stein H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 133: 1710-1715, 1984.
3. Hanna WM, Kahn HJ and Chapman JA: The correlation of Ki67 growth factor and ERICA in breast cancer. Mod Pathol 5: 220-223, 1992.
4. Nilsson S, Nordgren H, Eklov S and Logdahl M: Expression of Ki-67-a proliferation-associated-antigen-in prostatic cancer. Acta Oncol 30: 177-179, 1991.
5. Isola JJ, Helin HJ, Helle MJ and Kallioniemi OP: Evaluation of cell proliferation in breast carcinoma: Comparison of Ki-67 immunohistochemical study, DNA flow cytometric analysis, and mitotic count. Cancer 65: 1180-1184, 1990.
6. Yonemura Y, Ohoyama S, Kimura H et al: Assessment of tumor cell kinetics by monoclonal antibody Ki-67. Eur Surg Res 22: 365-370, 1990.
7. Cowen D, Troncoso P, Khoo VS et al: Ki-67 staining is an independent correlate of biochemical failure in prostate cancer treated with radiotherapy. Clin Cancer Res 8: 1148-1154, 2002.
8. Nakano T and Oka K: Transition of Ki-67 index of uterine cervical tumors during radiation therapy. Immunohistochemical study. Cancer 68: 517-523, 1991.
9. Shirasuna K, Sato M and Miyazaki T: A neoplastic epithelial duct cell line established from an irradiated human salivary gland. Cancer (Phila) 48: 745-752, 1981.
10. Martínez-Arribas F, Núñez MJ, Piqueras V et al: Flow cytometry vs. Ki67 labelling index in breast cancer: A prospective evaluation of 181 cases. Anticancer Res 22: 295-298, 2002.
11. McKenna WG, Iliakis G, Weiss MC et al: Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogene H-ras and v-myc. Radiat Res 125: 283-287, 1991.
12. Higuchi K, Nakano T, Tsuboi A et al: Flow cytometric and Ki-67 immunohistochemical analysis of cell cycle distribution of cervical cancer during radiation therapy. Anticancer Res 21: 2511-2518, 2001.
13. 3H]-thymidine. Cell Tissue Kinet 21: 271-283, 1988.
14. Szczepanski LV and Trott KR: Post-irradiation proliferation kinetics of a serially transplanted murine adenocarcinoma. Br J Radiol 48: 200-208, 1975.
15. Potmesil M and Goldfeder A: Cell kinetics of irradiated experimental tumors: Cell transition from the non-proliferating to the proliferating pool. Cell Tissue Kinet 13: 563-570, 1980.
16. Hermens AF and Barendsen GW: Changes of cell proliferation characteristics in a rat rhabdomyosarcoma before and after X-irradiation. Eur J Cancer 5: 173-189, 1969.
17. Fowler JF: Rapid repopulation in radiotherapy: A debate on mechanism. The phantom of tumor treatment-continually rapid proliferation unmasked. Radiother Oncol 22: 156-158, 1991.
18. Hall EJ: Cell, tissue, and tumor kinetics. In: Radiobiology for the Radiologist. Fourth edition. Philadelphia, J.B.Lippincott Company, 1994, pp 201.
19. Valente G, Orecchia R, Gandolfo S et al: Can Ki67 immunostaining predict response to radiotherapy in oral squamous cell carcinoma? J Clin Pathol 47: 109-112, 1994.
20. Nakano T, Oka K, Ishikawa A and Morita S: Immunohistochemical prediction of radiation response and local control in radiation therapy for cervical cancer. Cancer Detect Prevent 22: 120-128, 1998.
21. Oka K, Suzuki Y and Nakano T: High growth fraction at 9 grays of radiotherapy is associated with a good prognosis for patients with cervical squamous cell carcinoma. Cancer 89: 1526-1531, 2000.