Identification of teratogens in embryo cell culture. I. Laboratory values of rat embryo limb buds

Bulletin of the Veterinary Institute in Pulawy

Volumn 45, Issue 1, 2001, Pages 89-97

  Minta, Maria ^a  

^a NATIONAL VETERINARY RESEARCH INSTITUTE   (Poland)

Author keywords

Cell culture; Micromass assay; Rat embryo limb buds; Teratogenicity

Indexed keywords

EID: 1442317375     PISSN: 00424870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Ahrens P.B., Solursh M., Reiter R.S.: Stage related capacity for limb chondrogenesis in cell culture. Dev. Biol., 1977, 60, 69-82.
2. Archer C.W., Rooney P., Cottrill C.P.: Cartilage morphogenesis in vitro. J. Embryol. Exp. Morphol., 1985, 90, 33-48.
3. Bacon W. J., Duffy P.A., Jones K.: Studies on variability of the micromass teratogen test. Toxic. in Vitro, 1990, 4, 577-581.
4. Brown N.A., Wiger R.: Comparison of rat and chick limb bud micromass cultures for developmental toxicity screening. Toxic. in Vitro,1992, 6, 101-107
5. Cottrill C.P., Archer C.W., Wolper L.: Cell sorting and chondrogenic aggregate formation in micromass culture. Dev. Biol., 1987, 122, 503-515.
6. Creighton M.O., Mousa G.Y., Trevithick J.R.: Differentiation of rat lens epithelial cells in tissue culture. (I) Effects of cell density, medium and embryonic age of initial culture. Differentiation, 1976, 6, 155-167.
7. Faustman E.M.: Short-term tests for teratogens. Mutation Research., 1988, 205,355-384.
8. Flint O.P., Orton T.C.: An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells. Toxicol. Appl. Pharmacol., 1984, 76, 383-395.
9. Flint O.P.: An in vitro test for teratogens: its practical application. Fd. Chem. Toxicol., 1986, 24, 627-631.
10. Hattori T., Ide H.: Limb bud chondrogenesis in cell culture, with particular reference to serum concentration in the culture medium. Exp. Cell Res., 1984, 150, 338-346.
11. Kistler A., Mislin M., Gehring A.: Chondrogenesis of limb-bud cells: improved culture method and the effect of potent teratogen retinoic acid. Xenobiotica, 1985, 15, 673-679.
12. Kujawa M.J., Lennon D.P., Caplan A.I.: Growth and differentiation of stage 24 limb mesenchyme cells in serum-free chemically defined medium. Exp. Cell Res., 1989, 183, 45-61.
13. Newall D.R.: Strain difference in the response of embryonic cells to teratogens as determined in vitro using the micromass test. Teratology, 1990, 42, 28A.
14. Renault J.-Y., Caillaud J.M., Chevalier J.: Ultrastructural characterization of normal and abnormal chondrogenesis in micromass rat embryo limb bud cell cultures. Toxicol. Appl. Pharmacol., 1995, 130, 177-187.
15. Rodgers B.J., Kulyk W.M., Kosher R.A.: Stimulation of limb cartilage differentiation by cyclic AMP is dependent on cell density. Cell Differ. Dev., 1989, 28, 179-187.
16. Shi C., Muneoka K.: Position-specific growth of mouse limb bud cells in vitro. Dev. Biol., 1992, 151, 9-17.
17. Tsuchija T., Nakamura A., Iio T., Takahashi A.: Species differences between rats and mice in the teratogenic action of ethylenethiourea: in vivo/in vitro tests and teratogenic activity of sera using an embryonic cell differentiation system. Toxicol. Appl. Pharmacol., 1991, 109, 1-6.
18. Umansky R.: The effect of cell population density on the developmental fate of reaggregating mouse limb bud mesenchyme. Dev. Biol., 1966, 13, 31-56.
19. Uphill P.: In vitro micromass teratogen assay. INVITTOX Protocol Number 114, 1996.
20. Ward S.J., Newall D.R.: The micromass test: Is it subject to strain variation? Toxic, in vitro, 1990, 4, 620-622.