MALDI post-source decay and LIFT-TOF/TOF investigation of α-cyano-4-hydroxycinnamic acid cluster interferences

Journal of the American Society for Mass Spectrometry

Volumn 15, Issue 3, 2004, Pages 336-343

  Neubert, Hendrik ^a   Halket, John M ^a,b   Ocaña, Mireia Fernandez ^b   Patel, Raj K P ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DESORPTION; EVAPORATION; HYDROCHLORIC ACID; HYDROLYSIS; IONIZATION; MASS SPECTROMETRY; MOLECULAR STRUCTURE;

MATRIX ASSISTED LASER DESORPTION/IONIZATION (MALDI); MOLECULAR COMPOSITION;

ORGANIC ACIDS;

ALPHA CYANO 4 HYDROXYCINNAMIC ACID; GELATIN; GENTISIC ACID; HYDROCHLORIC ACID; PEPTIDE; POTASSIUM ION; SODIUM ION;

MASS SPECTROMETRY;

ARTICLE; CALIBRATION; CHEMICAL COMPOSITION; CLUSTER ANALYSIS; COMPLEX FORMATION; DECOMPOSITION; EVAPORATION; FRAGMENTATION REACTION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PEPTIDE ANALYSIS; PROTEIN HYDROLYSIS;

ANIMALS; COUMARIC ACIDS; GELATIN; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SWINE;

EID: 1442309138     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2003.11.002     Document Type: Article

References (23)

1. Aebersold R., Goodlett D.R. Mass Spectrometry in Proteomics. Chem. Rev. 101:2001;269-295.
2. Keller B.O., Li L. Detection of 25,000 Molecules of Substance P by MALDI-TOF Mass Spectrometry and Investigations into the Fundamental Limits of Detection in MALDI. J. Am. Soc. Mass Spectrom. 12:2001;1055-1063.
3. Dreisewerd K. The Desorption Process in MALDI. Chem. Rev. 103:2003;395-425.
4. Krutchinsky A.N., Chait B.T. On the Nature of the Chemical Noise in MALDI Mass Spectra. J. Am. Soc. Mass Spectrom. 13:2002;129-134.
5. Beavis R.C., Chait B.T. High-Accuracy Molecular Mass Determination of Proteins Using Matrix-Assisted Laser Desorption Mass Spectrometry. Anal. Chem. 62:1990;1836-1840.
6. O'Connor P.B., Mirgorodskaya E., Costello C.E. High Pressure Matrix-Assisted Laser Desorption/Ionization Fourier Transform Mass Spectrometry for Minimization of Ganglioside Fragmentation. J. Am. Soc. Mass Spectrom. 13:2002;402-407.
7. Karas M., Glückmann M., Schäfer J. Ionization in Matrix-Assisted Laser Desorption/Ionization Singly Charged Molecular Ions are the Lucky Survivors. J. Mass Spectrom. 35:2000;1-12.
8. Karas M., Krüger R. Ion Formation in MALDI The Cluster Ionization Mechanism. Chem. Rev. 103:2003;427-439.
9. Keller B.O., Li L. Discerning Matrix-Cluster Peaks in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectra of Dilute Peptide Mixtures. J. Am. Soc. Mass Spectrom. 11:2000;88-93.
10. Harris W.A., Janecki D.J., Reilly J.P. Use of Matrix Clusters and Trypsin Autolysis Fragments as Mass Calibrants in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Rapid Commun. Mass Spectrom. 16:2002;1714-1722.
11. Karty J.A., Ireland M.M.E., Brun Y.V., Reilly J.P. Artifacts and Unassigned Masses Encountered in Peptide Mass Mapping. J. Chromatogr. B. 782:2002;363-383.
12. Fernandez Ocaña, M.; Neubert, H.; Parker, R.; Bramley, P.; Halket, J.; Patel, R. BSE Control: Detection of Gelatine-Derived Peptides in Animal Feed by Mass Spectrometry. Analyst, in press
13. Gobom J., Müller M., Egelhofer V., Theiss D., Lehrach H., Nordhoff E. A Calibration Method that Simplifies and Improves Accurate Determination of Peptide Molecular Masses by MALDI-TOF MS. Anal. Chem. 74:2002;3915-3923.
14. La Rotta, A.; Holle, A. E.; Hillenkamp, F. LIFT: High Sensitivity Single Scan MALDI-TOF MS/MS. Proceedings of the 49th ASMS Annual Conference on Mass Spectrometry and Allied Topics; Chicago, IL, May, 2001
15. Suckau D., Resemann A., Schürenberg M., Hufnagel P., Franzen J., Holle A. A Novel MALDI LIFT-TOF/TOF Mass Spectrometer for Proteomics. Anal. Bioanal. Chem. 376:2003;952-965.
16. Schürenberg M., Lübbert C., Eickhoff H., Kalkum M., Lehrach H., Nordhoff E. Prestructured MALDI-MS Sample Supports. Anal. Chem. 72:2000;3436-3442.
17. Gobom J., Schürenberg M., Müller M., Theiss D., Lehrach H., Nordhoff E. α-Cyano-4-Hydroxycinnamic Acid Affinity Aample Preparation. A Protocol for MALDI-MS Peptide Analysis in Proteomics. Anal. Chem. 73:2001;434-438.
18. Karas M., Bahr U., Strupat K., Hillenkamp F., Tsarbopoulos A., Pramanik B.N. Matrix Dependence of Metastable Fragmentation of Glycoproteins in MALDI TOF Mass Spectrometry. Anal. Chem. 67:1995;675-679.
19. Gay S., Binz P.A., Hochstrasser D.F., Appel R.D. Modeling Peptide Mass Fingerprinting Data Using the Atomic Composition of Peptides. Electrophoresis. 20:1999;3527-3534.
20. Lee S.W., Kim H.S., Beauchamp J.L. Salt Bridge Chemistry Applied to Gas-Phase Peptide Sequencing Selective Fragmentation of Sodiated Gas-Phase Peptide Ions Adjacent to Aspartic Acid Residues. J. Am. Chem. Soc. 120:1998;3188-3195.
21. Lin T., Payne A.H., Glish G.L. Dissociation Pathways of Alkali-Cationized Peptides Opportunities for C-terminal Peptide Sequencing. J. Am. Soc. Mass Spectrom. 12:2001;497-504.
22. Cerda B.A., Cornett L., Wesdemiotis C. Probing the Interaction of Alkali and Transition Metal Ions with Bradykinin and its des-Arginine Derivatives via Matrix-Assisted Laser Desorption/Ionization and Postsource Decay Mass Spectrometry. Int. J. Mass Spectrom. 193:1999;205-226.
23. Dreisewerd K., Schürenberg M., Karas M., Hillenkamp F. Influence of the Laser Intensity and Spot Size on the Desorption of Molecules and Ions in Matrix-Assisted Laser-Desorption Ionization with a Uniform Beam Profile. Int. J. Mass Spectrom. Ion Processes. 141:1995;127-148.