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1
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0036720398
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The roles of FLT3 in hematopoiesis and leukemia
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Gilliland D.G., Griffin J.D. The roles of FLT3 in hematopoiesis and leukemia. Blood. 100:2002;1532-1542.
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Blood
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Gilliland, D.G.1
Griffin, J.D.2
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2
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0037097716
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Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
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Thiede C., Steudel C., Mohr B., Schaich M., Schakel U., Platzbecker U., Wermke M., Bornhauser M., Ritter M., Neubauer A., Ehninger G., Illmer T. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood. 99:2002;4326-4335.
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Blood
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Thiede, C.1
Steudel, C.2
Mohr, B.3
Schaich, M.4
Schakel, U.5
Platzbecker, U.6
Wermke, M.7
Bornhauser, M.8
Ritter, M.9
Neubauer, A.10
Ehninger, G.11
Illmer, T.12
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3
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16944366584
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Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia
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Horiike S., Yokota S., Nakao M., Iwai T., Sasai Y., Kaneko H., Taniwaki M., Kashima K., Fujii H., Abe T., Misawa S. Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia. Leukemia. 11:1997;1442-1446.
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Leukemia
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Horiike, S.1
Yokota, S.2
Nakao, M.3
Iwai, T.4
Sasai, Y.5
Kaneko, H.6
Taniwaki, M.7
Kashima, K.8
Fujii, H.9
Abe, T.10
Misawa, S.11
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4
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0037085745
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Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia
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Pedersen-Bjergaard J., Andersen M.K., Christiansen D.H., Nerlov C. Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia. Blood. 99:2002;1909-1912.
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Blood
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Pedersen-Bjergaard, J.1
Andersen, M.K.2
Christiansen, D.H.3
Nerlov, C.4
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6
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0036785393
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Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: Implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors
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Kottaridis P.D., Gale R.E., Langabeer S.E., Frew M.E., Bowen D.T., Linch D.C. Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors. Blood. 100:2002;2393-2398.
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Blood
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Kottaridis, P.D.1
Gale, R.E.2
Langabeer, S.E.3
Frew, M.E.4
Bowen, D.T.5
Linch, D.C.6
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7
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0035204051
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Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy
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Christiansen D.H., Pedersen-Bjergaard J. Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy. Leukemia. 15:2001;1848-1851.
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Leukemia
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Christiansen, D.H.1
Pedersen-Bjergaard, J.2
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8
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0038446667
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*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication
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*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication. Blood. 101:2003;2770-2774.
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(2003)
Blood
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Bowen, D.T.1
Frew, M.E.2
Rollinson, S.3
Roddam, P.L.4
Dring, A.5
Smith, M.T.6
Langabeer, S.E.7
Morgan, G.J.8
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9
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0035281739
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Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis
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Christiansen D.H., Andersen M.K., Pedersen-Bjergaard J. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol. 19:2001;1405-1413.
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J Clin Oncol
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Christiansen, D.H.1
Andersen, M.K.2
Pedersen-Bjergaard, J.3
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10
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0035383768
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FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia
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Stirewalt D.L., Kopecky K.J., Meshinchi S., Appelbaum F.R., Slovak M.L., Willman C.L., Radich J.P. FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia. Blood. 97:2001;3589-3595.
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Blood
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Stirewalt, D.L.1
Kopecky, K.J.2
Meshinchi, S.3
Appelbaum, F.R.4
Slovak, M.L.5
Willman, C.L.6
Radich, J.P.7
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11
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0037356973
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Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: Clinicopathological and karyotypic associations
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Au W.Y., Fung A., Man C., Ma S.K., Wan T.S., Liang R., Kwong Y.L. Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: clinicopathological and karyotypic associations. Br J Haematol. 120:2003;1062-1065.
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Br J Haematol
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Au, W.Y.1
Fung, A.2
Man, C.3
Ma, S.K.4
Wan, T.S.5
Liang, R.6
Kwong, Y.L.7
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12
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0036850573
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Alterations of the FLT3 gene in acute promyelocytic leukemia: Association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol
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Noguera N.I., Breccia M., Divona M., Diverio D., Costa V., De Santis S., Avvisati G., Pinazzi M.B., Petti C., Mandelli F., Lo Coco F. Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol. Leukemia. 16:2002;2185-2189.
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Leukemia
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Noguera, N.I.1
Breccia, M.2
Divona, M.3
Diverio, D.4
Costa, V.5
De Santis, S.6
Avvisati, G.7
Pinazzi, M.B.8
Petti, C.9
Mandelli, F.10
Lo Coco, F.11
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13
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0037062350
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PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model
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Kelly L.M., Kutok J.L., Williams I.R., Boulton C.L., Amaral S.M., Curley D.P., Ley T.J., Gilliland D.G. PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model. Proc Natl Acad Sci U S A. 99:2002;8283-8288.
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(2002)
Proc Natl Acad Sci U S a
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, pp. 8283-8288
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Kelly, L.M.1
Kutok, J.L.2
Williams, I.R.3
Boulton, C.L.4
Amaral, S.M.5
Curley, D.P.6
Ley, T.J.7
Gilliland, D.G.8
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