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Volumn 149, Issue 2, 2004, Pages 169-172

Low frequency of FLT3 gene internal tandem duplication and activating loop mutation in therapy-related acute myelocyticleukemia and myelodysplastic syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BLAST CELL; BLOOD CELL COUNT; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FMS RELATED TYROSINE KINASE 3 GENE; GENE; GENE DUPLICATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; MYELODYSPLASTIC SYNDROME; MYELOID LEUKEMIA; PATHOGENESIS; PRIORITY JOURNAL; SCHOOL CHILD; TANDEM REPEAT;

EID: 1442299812     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2003.07.007     Document Type: Article
Times cited : (12)

References (13)
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  • 2
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    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
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  • 4
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    • Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia
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    • Pedersen-Bjergaard, J.1    Andersen, M.K.2    Christiansen, D.H.3    Nerlov, C.4
  • 6
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    • Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: Implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors
    • Kottaridis P.D., Gale R.E., Langabeer S.E., Frew M.E., Bowen D.T., Linch D.C. Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors. Blood. 100:2002;2393-2398.
    • (2002) Blood , vol.100 , pp. 2393-2398
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  • 7
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    • Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy
    • Christiansen D.H., Pedersen-Bjergaard J. Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy. Leukemia. 15:2001;1848-1851.
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    • Christiansen, D.H.1    Pedersen-Bjergaard, J.2
  • 8
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    • *2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication
    • *2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication. Blood. 101:2003;2770-2774.
    • (2003) Blood , vol.101 , pp. 2770-2774
    • Bowen, D.T.1    Frew, M.E.2    Rollinson, S.3    Roddam, P.L.4    Dring, A.5    Smith, M.T.6    Langabeer, S.E.7    Morgan, G.J.8
  • 9
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    • Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis
    • Christiansen D.H., Andersen M.K., Pedersen-Bjergaard J. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol. 19:2001;1405-1413.
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  • 11
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    • Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: Clinicopathological and karyotypic associations
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.