Antibiotic Prophylaxis in Hip Fracture Surgery: A Metaanalysis

Clinical Orthopaedics and Related Research

Volumn 419, Issue , 2004, Pages 179-184

  Southwell Keely, James P ^a   Russo, Robert R ^a   March, Lyn ^a   Cumming, Robert ^a   Cameron, Ian ^a   Brnabic, Alan J M ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Research and Statistics Unit NSW   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFALOTIN; CEFAMANDOLE; CEFAZOLIN; CEFONICID; CEFOTIAM; CEFRADINE; CEFTRIAXONE; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; CLOXACILLIN; GLUCOSE; METICILLIN; NAFCILLIN; PLACEBO;

ANTIBIOTIC PROPHYLAXIS; ARTICLE; CLINICAL TRIAL; DISEASE ASSOCIATION; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; EMBASE; EVALUATION; HIP FRACTURE; HUMAN; INCIDENCE; INFORMATION RETRIEVAL; MEDLINE; META ANALYSIS; MORTALITY; MULTIPLE DRUG DOSE; OUTCOMES RESEARCH; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; STATISTICAL SIGNIFICANCE; URINARY TRACT INFECTION; WOUND INFECTION;

EID: 1442280089     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-200402000-00029     Document Type: Article

References (24)

1. Bodoky A, Neff U, Heberer M, Harder F. Antibiotic prophylaxis with two doses of cephalosorin in patients managed with internal fixation for a fracture of the hip. J Bone Joint Surg. 1993;75A:61-65.
2. Boyd RJ, Burke FJ, Colton T. A double blind clinical trial of prophylactic antibiotics in hip fractures. J Bone Joint Surg. 1973;55A: 1251-1258.
3. Buckley R, Hughes GNF, Snodgrass T, Huchcroft SA. Perioperative cefazolin prophylaxis in hip fracture surgery. Can J Surg. 1990;33:122-127.
4. Burnett JW, Gustilo RB, Williams DN, Kind AC. Prophylactic antibiotics in hip fractures: A double-blind prospective study. J Bone Joint Surg. 1980;62A:457-462.
5. Cook RJ, Sackett DL. The number needed to treat: A clinically useful measure of treatment effect. BMJ. 1995;310:452-454.
6. DerSimonian R, Laird N. Meta-analysis in clinical trials. Controlled Clinical Trials. 1986;7:177-188.
7. Ericson C, Lidgren L, Lindberg L. Cloxacillin in prophylaxis of postoperative infections of the hip. J Bone Joint Surg. 1973;55A:808-813.
8. Garcia S, Lozano ML, Gatell JM, et al. Prophylaxis against infection: Single dose cefonicid compared with multiple dose cefamandole. J Bone Joint Surg. 1991;73A:1044-1048.
9. Gatell JM, Garcia S, Lozano L, et al. Perioperative cefamandole prophylaxis against infections. J Bone Joint Surg. 1987;69A:1189-1193.
10. Guyatt GH, Sackett DL, Cook DJ. Users' guide to the medical literature: II. How to use an article about therapy on prevention: A. Are the results of the study valid? JAMA. 1993;270:2598-2601.
11. Guyatt GH, Sackett DL, Cook DJ. Users' guide to the medical literature: II. How to use an article about therapy on prevention: B. What were the results and will they help me in caring for my patients? JAMA. 1994;271:59-63.
12. Hedström SA, Lidgreen L, Sembo I, Törholm C, Önnerfält R. Cefuroxime prophylaxis in trochanteric hip fracture operations. Acta Orthop Scand. 1987;58:361-364.
13. Hjortrup A, Sørensen C, Mejdahl S, Horsnaes M, Kjersgaard P. Antibiotic prophylaxis in surgery for hip fractures. Acta Orthop Scand. 1990;61:152-153.
14. Karachalios T, Lyritis GP, Hatzopoulos E. Antibiotic prophylaxis in the surgical treatment of peritrochanteric fractures: A comparative trial between two cephalosporins. Chemotherapy. 1990;36:448-453.
15. Kaukonen JP, Kemppainen E, Mäkijämsi J, Touminen T. One dose cefuroxime prophylaxis on hip fracture surgery. Ann Chirurg Gynaecol. 1995;84:417-419.
16. Lindberg L, Tjornstrand B. Prophylactic use of cephradine against post-operative infections of pertrochanteric fractures. Arch Orthop Traumat Surg. 1978;92:189-190.
17. Luthje P, Nurmi I, Aho H, et al. Single-dose antibiotic prophylaxis in osteosynthesis for hip fractures: A clinical multicentre study in Finland. Ann Chirurg Gynaecol. 2000;89:125-130.
18. March L, Chamberlain A, Cameron I, et al. How best to fix a broken hip. Med J Aust. 1999;170:489-494.
19. McQueen MM, LittleJohn MA, Miles RS, Hughes SPF. Antibiotic prophylaxis in proximal femoral fracture. Injury. 1990;21:104-106.
20. Nelson CL, Green TG, Porter RA, Warren RD. One day versus seven days of preventive antibiotic therapy in orthopaedic surgery. Clin Orthop. 1983;175:258-263.
21. Petitti DB. Statistical Methods in Metaanalysis. In: Kelsey JL, Marmot MG, Stolley PD, Vessey MP (eds). Metaanalysis, Decision Analysis and Cost-Effectiveness Analysis. New York: Oxford University Press; 1994:90-114.
22. Schultz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias: Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA. 1995;273:408-412.
23. Tengve B, Kjellander J. Antibiotic prophylaxis in operations on trochanteric femoral fractures. J Bone Joint Surg. 1978;60A:408-499.
24. Todd W, Freeman W, Camillen-Ferrante C, et al. Differences in mortality after fracture of hip: The East Anglican audit. BMJ. 1995;310:904-908.