Recovery of apparent diffusion coefficient after embofic stroke does not signify complete salvage of post-ischemic neuronal tissue

Acta Neurochirurgica, Supplementum

Volumn , Issue 86, 2003, Pages 141-145

  Tanaka, Y ^a   Kuroiwa, T ^a   Miyasaka, N ^a   Tanabe, F ^a   Nagaoka, T ^b   Ohno, K ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cerebral ischemia; Embolus; Magnetic resonance imaging; Neuronal death; Rat

Indexed keywords

ANIMAL; ARTICLE; BRAIN; BRAIN EMBOLISM; BRAIN INFARCTION; CELL DEATH; CEREBROVASCULAR ACCIDENT; CONVALESCENCE; DIFFUSION; DIFFUSION WEIGHTED IMAGING; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RAT; TIME; WISTAR RAT;

ANIMALS; BRAIN; CELL DEATH; CEREBRAL INFARCTION; CEREBROVASCULAR ACCIDENT; DIFFUSION; DIFFUSION MAGNETIC RESONANCE IMAGING; INTRACRANIAL EMBOLISM; MALE; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; TIME FACTORS;

EID: 1442279299     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0651-8_30     Document Type: Article

References (9)

1. Busch E, Krueger K, Hossmann K-A (1997) Improved model of Ihrombocmbolic stroke and rt-PA induced reperfusion in the rat. Brain Res 778: 16-24
2. Hascgawa Y, Fisher M, Latour LL et al (1994) MRI diffusion mapping of reversible and irreversible ischemic injury in focal brain ischemia. Neurology 44: 1484-1490
3. Kaneko D, Nakamura N, Ogawa T (1985) Cerebral infarction in rats using homologous blood emboli: development of a new experimental model. Stroke 16: 76-84
4. Kudo M, Aoyama A, Ichimori S, Fukunaga N (1982) An animal model of cerebral infarction. Stroke 4: 505-508
5. Li F, Han SS, Tatlisumak T, et al (1999) Reversal of acute apparent diffusion coefficient abnormalities and delaye'd neuronal death following transient focal cerebral ischemia in rats. Ann Neurol 46: 333-342
6. Li F, Liu K-F, Silva MD, el al (2000) Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats. Stroke 31: 946-954
7. Minematsu R, Li L, Sotak CH, el al (1992) Reversible focal ischemic injury demonstrated by diffusion-weighted magnetic resonance imaging in rats. Stroke 23: 1304-1311
8. Miyasaka N, Nagaoka T, Kuroiwa T, el al (2000) Histopathologic collcrates of temporal diffusion changes in a rat model of cerebral hypoxia/ischcmia. AJNR 21: 60-66
9. Overgaard K, Sereghy T, Boyscn G, el al (1992) A rat model of reproducible cerebral infarction using thrombotic blood clot emboli. J Cereb DIood Flow Metab 12 (3): 484-490