"Brainprot" - Generating the proteome of the brain

Amino Acids

Volumn 26, Issue 1, 2004, Pages 1-2

  Lubec, G ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; PROTEOME;

BRAIN REGION; EDITORIAL; GENE EXPRESSION; NEUROANATOMY; NITROSYLATION; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEOMICS; REGULATORY MECHANISM;

EID: 1442276393     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-003-0044-6     Document Type: Editorial

References (21)

1. Bajo M, Fruehauf J, Kim SH, Fountoulakis M, Lubec G (2002) Proteomic evaluation of intermediary metabolism enzyme proteins in fetal Down's syndrome cerebral cortex. Proteomics 2: 1539-1546
2. Bernert G, Fountoulakis M, Lubec G (2002) Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain. Proteomics 2: 1752-1757
3. Engidawork E, Lubec G (2001) Protein expression in Down syndrome brain (Review). Amino Acids 21: 331-361
4. Fountoulakis M (2001) Proteomics: current technologies and applications in neurological disorders and toxicology. Amino Acids 21: 363-381
5. Fountoulakis M, Schuller E, Hardmeier R, Berndt P, Lubec G (1999) Rat brain proteins: two-dimensional protein database and variations in the expression level. Electrophoresis 20: 3572-3579
6. Fountoulakis M, Hardmaier R, Schuller E, Lubec G (2001a) Differences in protein level between neonatal and adult brain. Electrophoresis 21: 673-678
7. Fountoulakis M, Hardmeier R, Höger H, Lubec G (2001b) Postmortem changes in the level of brain proteins. Exp Neurol 167: 86-94
8. Fountoulakis M, Juranville JF, Dierssen M, Lubec G (2002) Proteomic analysis of the fetal brain. Proteomics 2: 1547-1576
9. Gulesserian T, Kim SH, Fountoulakis M, Lubec G (2002) Aberrant expression of centractin and capping proteins, integral constituents of the dynactin complex, in fetal Down syndrome brain. Biochem Biophys Res Commun 291: 62-67
10. Karlsson K, Cairns N, Lubec G, Fountoulakis M (1999) Enrichment of human brain proteins by heparin chromatography. Electrophoresis 20: 2970-2976
11. Kim SH, Fountoulakis M, Cairns NJ, Lubec G (2002) Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome. Biochem Biophys Res Commun 296: 970-975
12. Krapfenbauer K, Berger M, Lubec G, Fountoulakis M (2001) Changes in the brain protein levels following administration of kainic acid. Electrophoresis 22: 2086-2091
13. Krapfenbauer K, Yoo BC, Fountoulakis M, Mitrova E, Lubec G (2002) Expression patterns of antioxidant proteins in brains of patients with sporadic Creutzfeldt-Jacob disease. Electrophoresis 23: 2541-2547
14. Krapfenbauer K, Fountoulakis M, Lubec G (2003) A rat brain protein expression map including cytosolic and enriched mitochondrial and microsomal fractions. Electrophoresis 24: 1847-1870
15. Langen H, Berndt P, Roder D, Cairns N, Lubec G, Fountoulakis M (1999) Two-dimensional map of human brain proteins. Electrophoresis 20: 907-916
16. Lubec G, Krapfenbauer K, Fountoulakis M (2003) Proteomics in brain research: potentials and limitations. Prog Neurobiol 69: 193-211
17. Peyril A, Weitzdoerfer R, Gulesserian T, Fountoulakis M, Lubec G (2002) Aberrant expression of signaling-related proteins 14-3-3 gamma and RACK1 in fetal Down syndrome brain (trisomy 21). Electrophoresis 23: 152-157
18. Seidl R, Labudova O, Krapfenbauer K, Henriksson EW, Craft J, Turhani-Schatzmann D, Achsel T, Bidmon B, Pruijn GJ, Cairns N, Lubec G (2001) Deficient brain snRNP70K in patients with Down syndrome. Electrophoresis 22: 43-48
19. Weitzdoerfer R, Fountoulakis M, Lubec G (2002) Reduction of actin-related protein complex 2/3 in fetal Down syndrome brain. Biochem Biophys Res Commun 293: 836-841
20. Yoo BC, Fountoulakis M, Cairns N, Lubec G (2001) Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome. Electrophoresis 22: 172-179
21. Yoo BC, Vlkolinsky R, Engidawork E, Cairns N, Fountoulakis M, Lubec G (2001) Differential expression of molecular chaperones in brain of patients with Down syndrome. Electrophoresis 22: 1233-1241