Expression and characterization of the first kunitz domain of human tissue factor pathway inhibitor-2

Biochemical and Biophysical Research Communications

Volumn 324, Issue 4, 2004, Pages 1179-1185

  Kong, Desheng ^a   Ma, Duan ^a   Bai, Hao ^a   Guo, Hongshen ^a   Cai, Xu ^a   Mo, Wei ^a   Tang, Qiqun ^a   Song, Houyan ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Human tissue factor pathway inhibitor 2; Kunitz domain; Pichia pastoris; Plasmin; Protein expression; Purification; Trypsin

Indexed keywords

GELATINASE A; GELATINASE B; MATRIGEL; PLACENTA PROTEIN 5; PLASMIN; SERINE PROTEINASE INHIBITOR; TRYPSIN; GLYCOPROTEIN; MATRIX METALLOPROTEINASE; RECOMBINANT PROTEIN; TISSUE-FACTOR-PATHWAY INHIBITOR 2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; STRUCTURE ANALYSIS; ZYMOGRAPHY; CANCER INVASION; CHEMISTRY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PICHIA; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

CELL LINE, TUMOR; GLYCOPROTEINS; HUMANS; MATRIX METALLOPROTEINASES; NEOPLASM INVASIVENESS; PICHIA; PLASMIN; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRYPSIN;

EID: 14344262864     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.09.179     Document Type: Article

References (43)

1. C.N. Rao, P. Reddy, and Y. Liu Extracellular matrix-associated serine protease inhibitors (Mr 33,000, 31,000, and 27,000) are single-gene products with differential glycosylation: cDNA cloning of the 33-kDa inhibitor reveals its identity to tissue factor pathway inhibitor-2 Arch. Biochem. Biophys. 335 1996 82 92
2. M. Iino, D.C. Foster, and W. Kisiel Quantification and characterization of human endothelial cell-derived tissue factor pathway inhibitor-2 Arterioscler. Thromb. Vasc. Biol. 18 1998 40 46
3. C.N. Rao, Y.Y. Liu, and C.L. Peavey Novel extracellular matrix-associated serine proteinase inhibitors from human skin fibroblasts Arch. Biochem. Biophys. 104 1995 311 314
4. M.P. Herman, G.K. Sukhova, and W. Kisiel Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis J. Clin. Invest. 107 2001 1117 1126
5. C.N. Rao, B. Cook, Y.Y. Liu, and K. Chilukuri HT-1080 fibrosarcoma cell matrix degradation and invasion are inhibited by the matrix-associated serine protease inhibitor TFPI-2/33 kDa MSPI Int. J. Cancer 75 1998 749 756
6. H.S. Chand, X. Du, D. Ma, H.D. Inzunza, and S. Kamei The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic mice Blood 103 2004 1069 1077
7. S.D. Konduri, K.S. Srivenugopal, and N. Yanamandra Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells Oncogene 22 2003 4509 4516
8. S.D. Konduri, N. Yanamandra, and D.H. Dinh Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells Int. J. Oncol. 22 2003 1277 1283
9. S.D. Konduri, F.A. Osman, and C.N. Rao Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas Oncogene 21 2002 921 928
10. S.D. Konduri, C.N. Rao, and N. Chandrasekar A novel function of tissue factor pathway inhibitor-2 (TFPI-2) in human glioma invasion Oncogene 20 2001 6938 6945
11. A. Tasiou, S.D. Konduri, Y. Yanamandra, and D.H. Dinh A novel role of tissue factor pathway inhibitor-2 in apoptosis of malignant human gliomas Int. J. Oncol. 19 2001 591 597
12. C.N. Rao, S.S. Lakka, S.D. Konduri, and Y. Kin Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas Clin. Cancer Res. 7 2001 570 576
13. R. Zhong, R.B. Huang, and S.J. Song Role of tissue factor pathway inhibitor-2 in ovarian tumor migration and invasion Ai Zheng 22 2003 1038 1041
14. M. Jin, K. Udagawa, and E. Miyagi Expression of serine proteinase inhibitor PP5/TFPI-2/MSPI decreases the invasive potential of human choriocarcinoma cells in vitro and in vivo Gynecol. Oncol. 83 2001 325 333
15. S.D. Konduri, A. Tasiou, and N. Chandrasekar Role of tissue factor pathway inhibitor-2 (TFPI-2) in amelanotic melanoma (C-32) invasion Clin. Exp. Metastasis 18 2000 303 308
16. S.S. Lakka, S.D. Konduri, and S. Mohanam In vitro modulation of human lung cancer cell line invasiveness by antisense cDNA of tissue factor pathway inhibitor-2 Clin. Exp. Metastasis 18 2000 239 244
17. C.N. Rao, S. Mohanam, A. Puppala, and J.S. Rao Regulation of ProMMP-1 and ProMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor Biochem. Biophys. Res. Commun. 255 1999 94 99
18. H. Izumi, C. Takahashi, J. Oh, and M. Noda Tissue factor pathway inhibitor-2 suppresses the production of active matrix metalloproteinase-2 and is down-regulated in cells harboring activated ras oncogenes FEBS Lett. 481 2000 31 36
19. J.T. Crawley, D.A. Goulding, V. Ferreira, N.J. Severs, and F. Lupu Expression and localization of tissue factor pathway inhibitor-2 in normal and atherosclerotic human vessels Arterioscler. Thromb. Vasc. Biol. 22 2002 218 224
20. S. Kamei, and L.C. Petersen Inhibitory properties of human recombinant Arg24 Gln Type-2 tissue factor pathway inhibitor (R24Q TFPI-2) Thromb. Res. 94 1999 147 152
21. F. Hube, P. Reverdiau, S. Iochmann, and Y. Gruel Computer model of the interaction of human TFPI-2 Kunitz-type serine protease inhibitor with human plasmin Thromb. Res. 111 2003 197 198
22. H.S. Chand, A.E. Schmidt, S.P. Bajaj, and W. Kisiel Structure function analysis of the reactive site in the first kunitz-type domain of human tissue factor pathway inhibitor-2 J. Biol. Chem. 279 2004 17500 17507
23. M.J.M. Burgering, and L.P.M. Orbons The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa J. Mol. Biol. 269 1997 395 407
24. S. Mine, and T. Yamazaki Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor Biochemistry 41 2002 78 85
25. C.A. Sprecher, W. Kisiel, S. Mathewes, and D.C. Foster Molecular cloning, expression, and partial characterization of a second human tissue-factor- pathway inhibitor Proc. Natl. Acad. Sci. USA 91 1994 3353 3357
26. L.C. Petersen, C.A. Sprecher, D.C. Foster, H. Blumberg, and W. Kisiel Inhibitory properties of a novel human Kunitz-type protease inhibitor homologous to tissue factor pathway inhibitor Biochemistry 35 1996 266 272
27. J.G. Bieth In vivo significance of kinetic constants of protein proteinase inhibitors Biochem. Med. 32 1984 387 397
28. M. Nakajima, D.R. Welch, P.N. Belloni, and G.L. Nicolson Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials Cancer Res. 47 1987 4869 4876
29. M. Nakajima, D. Lotan, M.M. Baig, R.M. Carralero, W.R. Wood, M.J. Hendrix, and R. Lotan Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells Cancer Res. 49 1989 1698 1706
30. A. Albini, H. Iwamoto, H.K. Kleinman, G.R. Martin, S.A. Aaronson, J.M. Kozlowski, and R.N. Mcewan A rapid in vitro assay for quantitating the invasive potential of tumor cells Cancer Res. 47 1987 3239 3245
31. C.N. Rao, B. Cook, Y. Liu, K. Chilykuri, and M. Sharon Stack HT-1080 fibrosarcoma cell matrix degradation and invasion are inhibited by the matrix-associated serine protease inhibitor TFPI-2/33 kDa MSPI Int. J. Cancer 76 1998 749 756
32. G.A. Soff, J. Sanderowitz, S. Gately, E. Verrusio, I. Weiss, S. Brem, and H.C. Kwaan Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model J. Clin. Invest. 96 1995 2593 2600
33. H. Kobayashi, T. Yagyu, K. Inagaki, T. Kondo, M. Suzuki, N. Kanayama, and T. Terao Therapeutic efficacy of once-daily oral administration of a Kunitz-type protease inhibitor, bikunin, in a mouse model and in human cancer Cancer 100 2004 869 877
34. J.L. Bennetzen, and B.D. Hall Codon selection in yeast J. Biol. Chem. 257 1982 3026 3031
35. M.A. Romanos, C.A. Scorer, and J.J. Clare Foreign gene expression in yeast: a review Yeast 8 1992 423 488
36. R. Montesino, R. Garcia, O. Quintero, and J.A. Cremata Variation in N-linked oligosaccharide structures on heterologous proteins secreted by the methylotrophic yeast Pichia pastoris Protein Expr. Purif. 14 1998 197 207
37. M.F. Verostek, and R.B. Trimble Mannosyltransferase activity in membranes from various yeast strains Glycobiology 5 1995 671 681
38. K. Mizuno, T. Nakamura, T. Ohshima, S. Tanaka, and H. Matsuo Characterization of KEX2-encoded endopeptidase from yeast Saccharomyces cerevisiae Biochem. Biophys. Res. Commun. 159 1989 305 311
39. J.L. Cereghino, and J.M. Cregg Heterologous protein expression in the methylotrophic yeast Pichia pastoris FEMS Microbiol. Rev. 24 2000 45 66
40. L.M. Coussens, and Z. Werb Matrix metalloproteinases and the development of cancer Chem. Biol. 3 1996 895 904
41. J. Green Molecular cloning and characterization of human tissue inhibitor of metalloproteinase J. Biol. Chem. 271 1996 30375 30380
42. F. Willenbrock, and G. Murphy Structure-function relationships in the tissue inhibitors of metalloproteinases Am. J. Resp. Crit. Care Med. 150 1994 5165 5170
43. A.J. Docherty Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity Nature 318 1985 66 69