Body position and the neuroendocrine response to insulin-induced hypoglycemia in healthy subjects

Archives of Physiology and Biochemistry

Volumn 111, Issue 4, 2003, Pages 399-405

  Radikova, Zofia ^a   Penesova, A ^a   Jezova, D ^a   Kvetnansky, R ^a   Vigas, M ^a   Macho, L ^a   Koska, J ^a  

^a INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

Author keywords

Body position; Counterregulatory hormones; Glycemic thresholds; Hypoglycemia; Volume regulating hormones

Indexed keywords

ADRENALIN; ALDOSTERONE; CATECHOLAMINE; CORTICOTROPIN; GROWTH HORMONE; HYDROCORTISONE; MONOCOMPONENT INSULIN; NORADRENALIN; POTASSIUM ION; PROLACTIN; RENIN; SODIUM ION;

ADULT; BODY FLUID; BODY POSITION; CATECHOLAMINE BLOOD LEVEL; CONFERENCE PAPER; FEMALE; GLUCOSE BLOOD LEVEL; HEAD TILTING; HUMAN; HUMAN EXPERIMENT; HYPOGLYCEMIA; INSULIN INFUSION; MALE; NEUROENDOCRINE SYSTEM; NORMAL HUMAN; PLASMA RENIN ACTIVITY; PLASMA VOLUME; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SITTING; STANDING;

ADRENOCORTICOTROPIC HORMONE; ADULT; CATECHOLAMINES; ELECTROLYTES; FEMALE; HUMAN GROWTH HORMONE; HUMANS; HYDROCORTISONE; HYPOGLYCEMIA; INSULIN; MALE; NEUROSECRETORY SYSTEMS; PLASMA VOLUME; PROLACTIN; RENIN-ANGIOTENSIN SYSTEM;

EID: 14344260976     PISSN: 13813455     EISSN: None     Source Type: Journal    
DOI: 10.1080/13813450312331337658     Document Type: Conference Paper

References (41)

1. Baisch JF, Wolfram G, Beck L, Drummer C, Stormer I, Buckey J, Blomqvist G (2000): Orthostatic stress is necessary to maintain the dynamic range of cardiovascular control in space. Pflugers Arch 441: R52-61.
2. Blomqvist CG, Stone HL (1983): Cardiovascular adjustments to gravitational stress. In: Shepherd JT, Abboud FM, eds., Handbook of Physiology, The Cardiovascular System, Peripheral Circulation and Organ Blood Flow. Sect. 2, vol. 3, American Physiological Society, Bethesda, pp. 1025-1063.
3. Bolli GB, Fanelli CG (1999): Physiology of glucose counter-regulation to hypoglycemia. Endocrinol Metab Clin North Am 28: 467-493.
4. Cryer PE (1993): Glucose counterregulation: prevention and correction of hypoglycemia in humans. Am J Physiol 264: E149-E155.
5. Davis SN, Shavers C, Costa F (2000): Differential gender responses to hypoglycemia are due to alterations in CNS drive and not glycemic thresholds. Am J Physiol Endocrinol Metab 279: E1054-E1063.
6. De Feo P, Perriello G, Torlone E, Ventura MM, Santeusanio F, Brunetti P, Gerich JE, Bolli GB (1989a): Demonstration of a role for growth hormone in glucose counterregulation. Am J Physiol 256: E835-E843.
7. De Feo P, Perriello G, Torlone E, Ventura MM, Fanelli C, Santeusanio F, Brunetti P, Gerich JE, Bolli GB (1989b): Contribution of cortisol to glucose counterregulation in humans. Am J Physiol 257: E35-E42.
8. Dirschedl P, Gregull A, Lollgen H (1992): Volume loading of the heart by 'leg up' position and head down tilting (-6 degrees) (HDT). Acta Astronaut 27: 41-43.
9. Fanelli C, Pampanelli S, Epifano L, Rambotti AM, Ciofetta M, Moda F, Di Vincenzo A, Annibale B, Lepore M, Lalli C, Del Sindaco P, Brunetti P, Bolli GB (1994): Relative roles of insulin and hypoglycaemia on induction of neuroendocrine responses to, symptoms of, and deterioration of cognitive function in hypoglycaemia in male and female humans. Diabetologia 37: 797-807.
10. Gerich J, Cryer P, Rizza R (1980): Hormonal mechanisms in acute glucose counterregulation: The relative roles of glucagon, epinephrine, norepinephrine, growth hormone and cortisol. Metabolism 29 (Suppl. 1): 1164-1175.
11. Goldstein DS, Vernikos J, Holmes C, Convertino VA (1995): Catecholaminergic effects of prolonged head-down bed rest. J Appl Physiol 78: 1023-1029.
12. Greenleaf JE, Convertino VA, Mangseth GR (1979): Plasma volume during stress in man: osmolality and red cell volume. J Appl Physiol 47: 1031-1038.
13. Hinghofer-Szalkay HG, Sauseng-Fellegger G, Greenleaf JE (1995): Plasma volume with alternating tilting: effect of fluid ingestion. J Appl Physiol 78: 1369-1373.
14. Hinghofer-Szalkay HG, Vigas M, Sauseng-Fellegger EM, Lichardus B, Jezova D (1996): Head-up tilt and lower body suction: comparison of hormone responses in healthy men. Physiol Res 45: 369-378.
15. Hucklebridge F, Mellins J, Evans P, Clow A (2002): The awakening cortisol response: no evidence for an influence of body posture. Life Sci 71: 639-646.
16. Jacob G, Ertl AC, Shannon JR, Furlan R, Robertson RM, Robertson D (1998): Effect of standing on neurohumoral responses and plasma volume in healthy subjects. J Appl Physiol 84: 914-921.
17. Jezova D, Kvetnansky R, Kovacs K, Oprsalova Z, Vigas M, Makara GB (1987): Insulin-induced hypoglycemia activates the release of adrenocorticotropin predominantly via central and propranolol insensitive mechanisms. Endocrinology 120: 409-415.
18. Jezova D, Vigas M (1988): Apomorphine injection stimulates beta-endorphin, adrenocorticotropin, and cortisol release in healthy man. Psychoneuroendocrinology 13: 479-485.
19. Kinsley BT, Simonson DC (1996): Evidence for a hypothalamic-pituitary versus adrenal cortical effect of glycemic control on counterregulatory hormone responses to hypoglycemia in insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 81: 684-691.
20. Kinsley BT, Levy CJ, Simonson DC (1996): Prolactin and beta endorphin responses to hypoglycemia are reduced in well-controlled insulin-dependent diabetes mellitus. Metabolism 45: 1434-1440.
21. Koska J, Blazicek P, Marko M, Grna JD, Kvetnansky R, Vigas M (2000): Insulin, catecholamines, glucose and antioxidant enzymes in oxidative damage during different loads in healthy humans. Physiol Res 49: S95-S100.
22. Koska J, Ksinantova L, Kvetnansky R, Marko M, Hamar D, Vigas M, Hatala R: Effect of head-down bed rest on the neuroendocrine response to orthostatic stress in physically fit men. accepted in Physiol Res.
23. Ksinantova L, Koska J, Kvetnansky R, Marko M, Hamar D, Vigas M (2002): Effect of simulated microgravity on endocrine response to insulin-induced hypoglycemia in physically fit men. Horm Metab Res 34: 155-159.
24. Laszlo Z, Rossler A, Hinghofer-Szalkay HG (2001): Cardiovascular and hormonal changes with different angles of head-up tilt in men. Physiol Res 50: 71-82.
25. Levy CJ, Kinsley BT, Bajaj M, Simonson DC (1998): Effect of glycemic control on glucose counterregulation during hypoglycemia in NIDDM. Diabetes Care 21: 1330-1338.
26. Maggs DG, MacDonald IA (1994): Physiological and symptomatic responses to postural change in non-diabetic subjects during hypoglycemia. Clin Sci (Lond) 87: 193-199.
27. Maillet A, Gauquelin G, Gunga HC, Fortrat JO, Kirsch K, Guell A, Bizollon ChA, Gharib C (1995): Blood volume regulating hormones response during two space related simulation protocols: four-week confinement and head-down bed-rest. Acta Astronautica 35: 547-552.
28. Maw GJ, Mackenzie IL, Taylor NA (1995): Redistribution of body fluids during postural manipulations. Acta Physiol Scand 155: 157-163.
29. McGuire EA, Helderman JH, Tobin JD, Andres R, Berman M (1976): Effects of arterial versus venous sampling on analysis of glucose kinetics in man. J Appl Physiol 41: 565-573.
30. Mitrakou A, Ryan C, Veneman T, Mokan M, Jenssen T, Kiss I, Durrant J, Cryer P, Gerich J (1991): Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. Am J Physiol Endocrinol Metab 260: E67-E74.
31. Norsk P (1997): Gravitational stress and fluid volume regulation: a suggestion for revision of current hypotheses. J Gravit Physiol 4: 85-88.
32. Peuler J, Johnson GA (1977): Simultaneous single isotope radioenzymatic assay of plasma norepinephrine and dopamine. Life Sci 21: 625-638.
33. Robinson AM, Parkin HM, Macdonald IA, Tattersall RB (1994): Physiological response to postural change during mild hypoglycaemia in patients with IDDM. Diabetologia 37: 1241-1250.
34. Savin E, Bailliart O, Checoury A, Bonnin P, Grossin C, Martineaud JP (1995): Influence of posture on middle cerebral artery mean flow velocity in humans. Eur J Appl Physiol Occup Physiol 71: 161-165.
35. Schwartz NS, Clutter WE, Shah SD, Cryer PE (1987): Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms. J Clin Invest 79: 777-781.
36. Sotsky MJ, Shilo S, Shamoon H (1989): Regulation of counterregulatory hormone secretion in man during exercise and hypoglycemia. J Clin Endocrinol Metab 68: 9-16.
37. Strauss MB, Davis RK, Rosenbaum JD, Rossmeisl EC (1951): 'Water diuresis' produced during recumbency by the intravenous infusion of isotonic saline solution. J Clin Invest 30: 862-868.
38. Tsigos C, Chrousos GP (2002): Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J Psychosom Res 53: 865-871.
39. Vargas E, Lye M, Faragher EB, Goddard C, Moser B, Davies I (1986): Cardiovascular haemodynamics and the response of vasopressin, aldosterone, plasma renin activity and plasma catecholamines to head-up tilt in young and old healthy subjects. Age Ageing 15: 17-28.
40. Vigas M, Kvetnansky R, Jurcovicova J, Jezova D, Tatar P (1984): Comparison of catecholamine and adenopituitary hormone responses to various stress stimuli in man. In: Usdin E, Kvetnansky R, J Axelrod J, eds., Stress: The role of Catecholamines and Other Neurotransmitters. Gordon and Breach Sci. Pub., New York, pp. 865-882.
41. Vigas M, Klimes I, Jurcovicova J, Jezova D (1993): Acute elevation of endogenous prolactin does not influence glucose homeostasis in healthy men. Physiol Res 42: 341-345.