Use of binding enthalpy to drive an allosteric transition

Biochemistry

Volumn 44, Issue 8, 2005, Pages 3112-3121

  Brown, Patrick H ^a   Beckett, Dorothy ^a  

^a Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOSYNTHESIS; CALORIMETRY; CHEMICAL ACTIVATION; CHEMICAL BONDS; DIMERIZATION; DNA; ESCHERICHIA COLI; FREE ENERGY; MONOMERS; THERMODYNAMICS; TITRATION; VITAMINS;

BIOTIN; DNA BINDING PROTEINS; ISOTHERMAL TITRATION CALORIMETRY;

PROTEINS;

BIOTIN; DNA BINDING PROTEIN; LIGAND; MONOMER;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; COVALENT BOND; DIMERIZATION; ENERGY TRANSFER; ENTHALPY; ESCHERICHIA COLI; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; BINDING SITES; CALORIMETRY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; REPRESSOR PROTEINS; THERMODYNAMICS;

EID: 14344255691     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047792k     Document Type: Article

References (29)

1. Matthews, K. S., Falcon, C. M., and Swint-Kruse, L. (2000) Relieving repression, Nat. Struct. Biol. 7, 184-187.
2. Tao, X., Zeng, H. Y., and Murphy, J. R. (1995) Transition metal ion activation of DNA binding by the diphtheria tox repressor requires the formation of stable homodimers, Proc. Natl. Acad. Sci. U.S.A. 92, 6803-6807.
3. Cronan, J. E., Jr. (1989) The E. coli bio operon: Transcriptional repression by an essential protein modification enzyme, Cell 58, 427-429.
4. Barker, D. F., and Campbell, A. M. (1981) Genetic and biochemical characterization of the birA gene and its product: Evidence for a direct role of biotin holoenzyme synthetase in repression of the biotin operon in Escherichia coli, J. Mol. Biol. 146, 469-492.
5. Barker, D. F., and Campbell, A. M. (1981) The birA gene of Escherichia coli encodes a biotin holoenzyme synthetase, J. Mol. Biol. 146, 451-461.
6. Lane, M. D., Rominger, K. L., Young, D. L., and Lynen, F. (1964) The enzymatic synthesis of holotranscarboxylase from apotranscarboxylase and (+)-biotin, J. Biol. Chem. 239, 2865-2871.
7. Otsuka, A., and Abelson, J. (1978) The regulatory region of the biotin operon in Escherichia coli, Nature 276, 689-694.
8. Prakash, O., and Eisenberg, M. A. (1979) Biotinyl 5′-adenylate: Corepressor role in the regulation of the biotin genes of Escherichia coli k-12, Proc. Natl. Acad. Sci. U.S.A. 76, 5592-5595.
9. Wilson, K. P., Shewchuk, L. M., Brennan, R. G., Otsuka, A. J., and Matthews, B. W. (1992) Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains, Proc. Natl. Acad. Sci. U.S.A. 89, 9257-9261.
10. Abbott, J., and Beckett, D. (1993) Cooperative binding of the Escherichia coli repressor of biotin biosynthesis to the biotin operator sequence, Biochemistry 32, 9649-9656.
11. Eisenstein, E., and Beckett, D. (1999) Dimerization of the Escherichia coli biotin repressor: Corepressor function in protein assembly, Biochemistry 38, 13077-13084.
12. Streaker, E. D., Gupta, A., and Beckett, D. (2002) The biotin repressor: Thermodynamic coupling of corepressor binding, protein assembly, and sequence-specific DNA binding, Biochemistry 41, 14263-14271.
13. Kwon, K., Streaker, E. D., Ruparelia, S., and Beckett, D. (2000) Multiple disordered loops function in corepressor-induced dimerization of the biotin repressor, J. Mol. Biol. 304, 821-833.
14. Streaker, E. D., and Beckett, D. (2003) Coupling of protein assembly and DNA binding: Biotin repressor dimerization precedes biotin operator binding, J. Mol. Biol. 325, 937-948.
15. Weaver, L. H., Kwon, K., Beckett, D., and Matthews, B. W. (2001) Corepressor-induced organization and assembly of the biotin repressor: A model for allosteric activation of a transcriptional regulator, Proc. Natl. Acad. Sci. U.S.A. 98, 6045-6050.
16. Brown, P. H., Cronan, J. E., Grotli, M., and Beckett, D. (2004) The biotin repressor: Modulation of allostery by corepressor analogs, J. Mol. Biol. 337, 857-869.
17. Sigurskjold, B. W. (2000) Exact analysis of competition ligand binding by displacement isothermal titration calorimetry, Anal. Biochem. 277, 260-266.
18. Pierce, M. M., Raman, C. S., and Nall, B. T. (1999) Isothermal titration calorimetry of protein-protein interactions, Methods 19, 213-221.
19. Christensen, J. J., Hansen, L. D., and Izattin, R. M., Eds. (1976) Handbook of proton ionisation heats and related thermodynamic quantities, John Wiley, New York.
20. Xu, Y., Nenortas, E., and Beckett, D. (1995) Evidence for distinct ligand-bound conformational states of the multifunctional Escherichia coli repressor of biotin biosynthesis, Biochemistry 34, 16624-16631.
21. Sigurskjold, B. W., Berland, C. R., and Svensson, B. (1994) Thermodynamics of inhibitor binding to the catalytic site of glucoamylase from Aspergillus niger determined by displacement titration calorimetry, Biochemistry 33, 10191-10199.
22. Jelesarov, I., and Bosshard, H. R. (1999) Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition, J. Mol. Recognit. 12, 3-18.
23. Leavitt, S., and Freire, E. (2001) Direct measurement of protein binding energetics by isothermal titration calorimetry, Curr. Opin. Struct. Biol. 11, 560-566.
24. Velazquez-Campoy, A., Kiso, Y., and Freire, E. (2001) The binding energetics of first- and second-generation hiv-1 protease inhibitors: Implications for drug design, Arch. Biochem. Biophys. 390, 169-175.
25. Xu, Y., Johnson, C. R., and Beckett, D. (1996) Thermodynamic analysis of small ligand binding to the Escherichia coli repressor of biotin biosynthesis, Biochemistry 35, 5509-5517.
26. Bains, G., and Freire, E. (1991) Calorimetric determination of cooperative interactions in high affinity binding processes, Anal. Biochem. 192, 203-206.
27. Ohtaka, H., Muzammil, S., Schon, A., Velazquez-Campoy, A., Vega, S., and Freire, E. (2004) Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets, Int. J. Biochem. Cell Biol. 36, 1787-1799.
28. Kwon, K., Streaker, E. D., and Beckett, D. (2002) Binding specificity and the ligand dissociation process in the E. coli biotin holoenzyme synthetase, Protein Sci. 11, 558-570.
29. Xu, Y., and Beckett, D. (1996) Evidence for interdomain interaction in the Escherichia coli repressor of biotin biosynthesis from studies of an N-terminal domain deletion mutant, Biochemistry 35, 1783-1792.