Kinetic versus thermodynamic access to imidazoisoindolones, benzimidazoisoindolones, and [1,4]diazepinoisoindolones: Intramolecular nitrogen and π-aromatic trapping of N-acyliminium cation

Tetrahedron

Volumn 60, Issue 48, 2004, Pages 11029-11039

  Cul, Armelle ^a   Daïch, Adam ^a   Decroix, Bernard ^a   Sanz, Gérard ^b   Van Hijfte, Luc ^b  

^a UNIVERSITÉ DU HAVRE   (France)

^b Johnson Johnson Pharmaceutical R   (France)

Author keywords

Benzimidazole; Imidazole; Isoindole; Kinetic versus thermodynamic control; N Acyliminium ion; 1,4 Diazepine; Aza amidoalkylation

Indexed keywords

10B METHOXY 10B,11 DIHYDROBENZO[4,5]IMIDAZO[2,1 A]ISOINDOL 6 ONE; 11 ACETYL 10B,11 DIHYDROBENZO[4,5]IMIDAZO[2,1 A]ISOINDOL 6 ONE; 2 METHYL 6 OXOISOINDOLO[2,1 A]BENZIMIDAZOLE; 6 OXOISOINDOLO[2,1 A]BENZIMIDAZOLE; AMINE; BENZIMIDAZOLE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CATION; DIAZEPINE DERIVATIVE; IMIDAZOLE DERIVATIVE; ISOINDOLE DERIVATIVE; NITROGEN; PHTHALIC ANHYDRIDE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; KINETICS; METHODOLOGY; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 14344254649     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.07.107     Document Type: Article

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