-
1
-
-
0032578635
-
Structure of a glutamate receptor ligand binding core in complex with kainate
-
Armstrong N, Sun Y, Chen GQ, and Gouaux E (1998) Structure of a glutamate receptor ligand binding core in complex with kainate. Nature (Lond) 395:913-917.
-
(1998)
Nature (Lond)
, vol.395
, pp. 913-917
-
-
Armstrong, N.1
Sun, Y.2
Chen, G.Q.3
Gouaux, E.4
-
2
-
-
12144271737
-
Protons trap NR1/NR2B receptors in a non-conducting state
-
in press
-
Banke T, Dravid SM, and Traynelis SF (2005) Protons trap NR1/NR2B receptors in a non-conducting state. J Neurosci (in press).
-
(2005)
J Neurosci
-
-
Banke, T.1
Dravid, S.M.2
Traynelis, S.F.3
-
3
-
-
0033103522
-
NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteines
-
Beck C, Wollmuth LP, Seeburg PH, Sakmann B, and Kuner T (1999) NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteines. Neuron 22:559-570.
-
(1999)
Neuron
, vol.22
, pp. 559-570
-
-
Beck, C.1
Wollmuth, L.P.2
Seeburg, P.H.3
Sakmann, B.4
Kuner, T.5
-
4
-
-
0023392945
-
High-efficiency transformation of mammalian cells by plasmid DNA
-
Chen C and Okayama H (1987) High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
5
-
-
0033136273
-
Identification and mechanism of action of two histidine residues underlying high affinity zinc inhibition of NMDA receptors
-
Choi Y-B and Lipton SA (1999) Identification and mechanism of action of two histidine residues underlying high affinity zinc inhibition of NMDA receptors. Neuron 23:171-180.
-
(1999)
Neuron
, vol.23
, pp. 171-180
-
-
Choi, Y.-B.1
Lipton, S.A.2
-
6
-
-
0032199006
-
Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
-
Colquhoun D (1998) Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125:924-947.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 924-947
-
-
Colquhoun, D.1
-
8
-
-
0033199996
-
Pathobiology of ischemic stroke: An integrated view
-
Dirnagl U, Iadecola C, and Moskowitz MA (1999) Pathobiology of ischemic stroke: an integrated view. Trends Neurosci 22:391-397.
-
(1999)
Trends Neurosci
, vol.22
, pp. 391-397
-
-
Dirnagl, U.1
Iadecola, C.2
Moskowitz, M.A.3
-
9
-
-
0038037859
-
Mechanisms of activation, inhibition and specificity: Crystal structure of the NMDA receptor NR1 ligand-binding core
-
Furukawa H and Gouaux E (2003) Mechanisms of activation, inhibition and specificity: crystal structure of the NMDA receptor NR1 ligand-binding core. EMBO (Eur Mol Biol Organ) J 22:2873-2885.
-
(2003)
EMBO (Eur Mol Biol Organ) J
, vol.22
, pp. 2873-2885
-
-
Furukawa, H.1
Gouaux, E.2
-
10
-
-
0037088901
-
The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening
-
Jones KS, Van Dongen HMA, and Van Dongen AMJ (2002) The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening. J Neurosci 22:2044-2053.
-
(2002)
J Neurosci
, vol.22
, pp. 2044-2053
-
-
Jones, K.S.1
Van Dongen, H.M.A.2
Van Dongen, A.M.J.3
-
11
-
-
0034114521
-
Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties
-
Kohda K, Wang Y, and Yuzaki M (2000) Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties. Nat Neurosci 3:315-322.
-
(2000)
Nat Neurosci
, vol.3
, pp. 315-322
-
-
Kohda, K.1
Wang, Y.2
Yuzaki, M.3
-
12
-
-
0033600277
-
The changing landscape of ischaemic brain injury mechanisms
-
Lee J-M, Zipfel G-J, and Choi DW (1999) The changing landscape of ischaemic brain injury mechanisms. Nature (Lond) 399:A7-A14.
-
(1999)
Nature (Lond)
, vol.399
-
-
Lee, J.-M.1
Zipfel, G.-J.2
Choi, D.W.3
-
13
-
-
0026601970
-
NMDA channel behavior depends on agonist affinity
-
Lester RA and Jahr CE (1992) NMDA channel behavior depends on agonist affinity. J Neurosci 12:635-643.
-
(1992)
J Neurosci
, vol.12
, pp. 635-643
-
-
Lester, R.A.1
Jahr, C.E.2
-
14
-
-
0037686667
-
Molecular determinants of proton sensitive NMDA receptor gating
-
Low C-M, Lyuboslavsky P, French A, Lee P, Wyatte K, Thiel WH, Marchan E, Igarashi K, Kashiwagi K, Gernert K, et al. (2003) Molecular determinants of proton sensitive NMDA receptor gating. Mol Pharmacol 63:1212-1222.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 1212-1222
-
-
Low, C.-M.1
Lyuboslavsky, P.2
French, A.3
Lee, P.4
Wyatte, K.5
Thiel, W.H.6
Marchan, E.7
Igarashi, K.8
Kashiwagi, K.9
Gernert, K.10
-
15
-
-
0034718494
-
Molecular determinants of coordinated proton and zinc inhibition of NMDA NR1/NR2A receptors
-
Low C-M, Zheng F, Lyuboslavsky P, and Traynelis SF (2000) Molecular determinants of coordinated proton and zinc inhibition of NMDA NR1/NR2A receptors. Proc Natl Acad Sci USA 97:11062-11067.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11062-11067
-
-
Low, C.-M.1
Zheng, F.2
Lyuboslavsky, P.3
Traynelis, S.F.4
-
16
-
-
0032860275
-
Glutamate receptors and transporters in genetic and acquired models of epilepsy
-
Meldrum BS, Akbar MT, and Chapman AG (1999) Glutamate receptors and transporters in genetic and acquired models of epilepsy. Epilepsy Res 36:189-204.
-
(1999)
Epilepsy Res
, vol.36
, pp. 189-204
-
-
Meldrum, B.S.1
Akbar, M.T.2
Chapman, A.G.3
-
17
-
-
0032234177
-
Phenylethanolamines inhibit NMDA receptors by enhancement of proton inhibition
-
Mott DD, Doherty JJ, Zhang S, Washburn MS, Fendley MJ, Lyuboslavsky P, Traynelis SF, and Dingledine R (1998) Phenylethanolamines inhibit NMDA receptors by enhancement of proton inhibition. Nat Neurosci 1:659-667.
-
(1998)
Nat Neurosci
, vol.1
, pp. 659-667
-
-
Mott, D.D.1
Doherty, J.J.2
Zhang, S.3
Washburn, M.S.4
Fendley, M.J.5
Lyuboslavsky, P.6
Traynelis, S.F.7
Dingledine, R.8
-
18
-
-
0030670737
-
Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury
-
Obrenovitch TP and Urenjak J (1997) Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury. J Neurotrauma 14:677-698.
-
(1997)
J Neurotrauma
, vol.14
, pp. 677-698
-
-
Obrenovitch, T.P.1
Urenjak, J.2
-
19
-
-
0030782939
-
Excitotoxic neurodegeneration in Alzheimer disease: New hypothesis and new therapeutic strategies
-
Olney JW, Wozniak DF, and Farber NB (1997) Excitotoxic neurodegeneration in Alzheimer disease: new hypothesis and new therapeutic strategies. Arch Neurol 54:1234-1240.
-
(1997)
Arch Neurol
, vol.54
, pp. 1234-1240
-
-
Olney, J.W.1
Wozniak, D.F.2
Farber, N.B.3
-
21
-
-
0030746608
-
High affinity zinc inhibition of NMDA NR1-NR2A receptors
-
Paoletti P, Ascher P, and Neyton J (1997) High affinity zinc inhibition of NMDA NR1-NR2A receptors. J Neurosci 17:5711-5725.
-
(1997)
J Neurosci
, vol.17
, pp. 5711-5725
-
-
Paoletti, P.1
Ascher, P.2
Neyton, J.3
-
22
-
-
0030899137
-
Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes
-
Park AJ and Williams K (1997) Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes. Neurosci Lett 225:29-32.
-
(1997)
Neurosci Lett
, vol.225
, pp. 29-32
-
-
Park, A.J.1
Williams, K.2
-
24
-
-
0037012062
-
Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating
-
Sobolevsky AI, Beck C, and Wollmuth LP (2002a) Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating. Neuron 33:75-85.
-
(2002)
Neuron
, vol.33
, pp. 75-85
-
-
Sobolevsky, A.I.1
Beck, C.2
Wollmuth, L.P.3
-
26
-
-
0034708631
-
The lurcher mutation of an α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist
-
Taverna F, Xiong Z-G, Brandes L, Roder JC, Salter MW, and MacDonald JF (2000) The lurcher mutation of an α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. J Biol Chem 275:8475-8479.
-
(2000)
J Biol Chem
, vol.275
, pp. 8475-8479
-
-
Taverna, F.1
Xiong, Z.-G.2
Brandes, L.3
Roder, J.C.4
Salter, M.W.5
MacDonald, J.F.6
-
27
-
-
0029021010
-
Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines
-
Traynelis SF, Hartley M, and Heinemann SF (1995) Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines. Science (Wash DC) 268:873-876.
-
(1995)
Science (Wash DC)
, vol.268
, pp. 873-876
-
-
Traynelis, S.F.1
Hartley, M.2
Heinemann, S.F.3
-
29
-
-
0034867583
-
Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A
-
Zheng F, Erreger K, Low C-M, Banke T, Lee CJ, Conn PJ, and Traynelis SF (2001) Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A. Nature Neurosci 4:894-901.
-
(2001)
Nature Neurosci
, vol.4
, pp. 894-901
-
-
Zheng, F.1
Erreger, K.2
Low, C.-M.3
Banke, T.4
Lee, C.J.5
Conn, P.J.6
Traynelis, S.F.7
|