Experimental studies on the effects of recombinant human matrix metalloproteinases on herniated disc tissues - How to facilitate the natural resorption process of herniated discs

Journal of Orthopaedic Research

Volumn 23, Issue 2, 2005, Pages 412-419

  Haro, Hirotaka ^a   Komori, Hiromichi ^b   Kato, Tsuyoshi ^b   Hara, Yasushi ^c   Tagawa, Masahiro ^c   Shinomiya, Kenichi ^b   Spengler, Dan M ^d  

^a Suwa Central Hospital   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chemonucleolysis; Herniated disc; Matrix metalloproteinase; Resorption

Indexed keywords

CHYMOPAPAIN; MATRILYSIN; PROTEOGLYCAN; RECOMBINANT PROTEIN; SODIUM CHLORIDE; STROMELYSIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMONUCLEOLYSIS; CONTROLLED STUDY; DOG; DRUG EXPOSURE; DRUG MECHANISM; HUMAN; HUMAN TISSUE; IN VIVO STUDY; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK HERNIA; MALE; MYELOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RABBIT; STAINING; TISSUE CULTURE; WESTERN BLOTTING;

ADULT; ANIMALS; CHYMOPAPAIN; DOGS; HUMANS; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DISPLACEMENT; MALE; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 7; MIDDLE AGED; ORGAN CULTURE TECHNIQUES; PROTEOGLYCANS; RABBITS; RECOMBINANT PROTEINS;

EID: 14244267047     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.orthres.2004.08.020     Document Type: Article

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