A murine model of ex vivo angiogenesis using aortic disks grown in fibrin clot

Microvascular Research

Volumn 68, Issue 3, 2004, Pages 179-187

  Berger, Adam C ^a   Wang, Xue Qing ^a   Zalatoris, Alice ^a   Cenna, Jonathan ^a   Watson, James C ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Angiogenesis; Endostatin; Immunohistochemistry; Murine models; Suramin

Indexed keywords

ANGIOGENESIS; CELL ISOLATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM; EX VIVO STUDY; FIBRIN CLOT; FLUORESCENCE ACTIVATED CELL SORTING; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 14244252824     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mvr.2004.05.005     Document Type: Conference Paper

References (13)

1. A.C. Berger, A.L. Feldman, M.F. Gnant, E.A. Kruger, B.K. Sim, S. Hewitt, W.D. Figg, H.R. Alexander, and S.K. Libutti The angiogenesis inhibitor, endostatin, does not affect murine cutaneous wound healing J. Surg. Res. 91 1 2000 26 31
2. G. Bocci, R. Danesi, U. Benelli, F. Innocenti, A. DiPaolo, S. Fogli, and M. Del Tacca Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo Cancer Chemother. Pharmacol. 43 3 1999 205 212
3. L. Devy, S. Blacher, C. Grignet-Debrus, K. Bajou, V. Masson, R.D. Gerard, A. Gils, G. Carmeliet, P. Carmeliet, P.J. Declerck, A. Noel, and J.M. Foidart The pro-or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent FASEB 16 2002 147 154
4. J. Folkman Tumor angiogenesis: therapeutic implications N. Engl. J. Med. 285 1971 1182 1186
5. M.A. Gimbrone, R.S. Cotran, S.B. Leapman, and J. Folkman Tumor growth and neovascularization: an experimental model using the rabbit cornea J. Natl. Cancer Inst. 52 1974 413 427
6. D. Knighton, D. Ausprunk, D. Tapper, and J. Folkman Avascular and vascular phases of tumor growth in the chick embryo Br. J. Cancer 35 1977 347 356
7. E.A. Kruger, P.H. Duray, M.G. Tsokos, D.J. Venzon, S.K. Libutti, S.C. Dixon, M.A. Rudek, J. Pluda, C. Allegra, and W.D. Figg Endostatin inhibits microvessel formation in the ex vivo rat aortic ring angiogenesis assay Biochem. Biophys. Res. Commun. 268 2000 183 191
8. E.A. Kruger, P.H. Duray, D.K. Price, J.M. Pluda, and W.D. Figg Approaches to preclinical screening of antiangiogenic agents Sem. Oncol. 28 6 2001 570 576
9. B. Lange-Asschenfeldt, P. Velasco, M. Streit, T. Hawighorst, S.E. Pike, G. Tosa, and M. Detmar The angiogenesis inhibitor vasostatin does not impair wound healing at tumor-inhibiting doses J. Invest. Dermatol. 117 5 2001 1036 1041
10. M. Nguyen, Y. Shing, and J. Folkman Quantification of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane Microvasc. Res. 47 1994 31 40
11. R.F. Nicosia, and A. Ottinetti Growth of microvessels in serum-free matrix culture of rat aorta: a quantitative assay of angiogenesis in vitro Lab. Invest. 63 1990 115 122
12. R.F. Nicosia, and A. Ottinetti Modulation of microvascular growth and morphogenesis by reconstituted basement membrane gel in three-dimensional cultures of rat aorta: a comparative study of angiogenesis in Matrigel, collagen, fibrin, and plasma clot In Vitro Cell. Dev. Biol. 26 1990 119 128
13. T.G. Zogakis, N.G. Costouros, E.A. Kruger, S. Forbes, M. He, M. Qian, A.L. Feldman, W.D. Figg, H.R. Alexander, E.T. Liu, E.C. Kohn, and S.K. Libutti Microarray gene expression profiling of angiogenesis inhibitors using the rat aortic ring assay BioTechniques 33 2002 664 670