Strategies for optimizing compliance of paediatric patients for seasonal antibacterial vaccination with sublingually administered Polyvalent Mechanical Bacterial Lysates (PMBL)

Acta Biomedica de l'Ateneo Parmense

Volumn 75, Issue 3, 2004, Pages

  Rosaschino, Filippo ^a,b   Cattaneo, Laura ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b NONE   (Italy)

Author keywords

Paediatric compliance; Polyvalent mechanical bacterial lysates; Recurrent respiratory infections; Sublingual

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BACTERIUM LYSATE; CREATININE; GAMMA GLUTAMYLTRANSFERASE; POLYVALENT MECHANICAL BACTERIAL LYSATE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTERIAL INFECTION; BONE MARROW TOXICITY; CHILD; CHILDHOOD DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG TOLERABILITY; FOLLOW UP; HUMAN; IMMUNE FUNCTION TEST; INFANT; KIDNEY FUNCTION; LABORATORY TEST; LIVER FUNCTION TEST; LIVER TOXICITY; MAJOR CLINICAL STUDY; NEPHROTOXICITY; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; RECURRENT INFECTION; RESPIRATORY TRACT INFECTION; TREATMENT OUTCOME; VACCINATION;

ADMINISTRATION, SUBLINGUAL; BACTERIA; BACTERIAL VACCINES; BIOLOGICAL MARKERS; CELL EXTRACTS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; IMMUNIZATION SCHEDULE; INFANT; KIDNEY FUNCTION TESTS; LEUKOCYTE COUNT; LIVER FUNCTION TESTS; LYMPHOCYTES; MALE; MOTIVATION; OTITIS MEDIA; PATIENT ACCEPTANCE OF HEALTH CARE; PATIENT COMPLIANCE; PILOT PROJECTS; RECURRENCE; RESPIRATORY TRACT INFECTIONS; SAMPLING STUDIES; SEASONS; VACCINATION;

EID: 14244249636     PISSN: 03924203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Wei SC, Norwood J. Diagnosis and management of respiratory tract infections for the primary care physician. Obstet Gynecol Clin North Am 2001; 28 (2): 283-304.
2. Barbuti S, Belleli S, Fara GM, Giammanco G. Epidemiologia e prevenzione delle infezioni trasmesse per via aerea. Igiene e medicina preventiva 1994; 2: 158-60.
3. West JV. Acute upper airway infections. Br Med Bull 2002; 61: 215-30.
4. Menec VH, Black C, Mac William L, Aoki FY. The impact of influenza-associated respiratory illnesses on hospitalisation, physicians visit, emergency room visit and mortality. Can J Public Health 2003; 94 (1): 59-63.
5. Izurieta HS, Thompson WW, Kramarz P, et al. Influenza and the rate of hospitalisation for respiratory disease among infants and young children. N Engl J Med 2000; 342: 232-9.
6. Blasi F. Vaccinoprofilassi delle infezioni respiratorie: efficacia di un lisato batterico per via meccanica. Gior It Mal Tor 2002; 56: 85-9.
7. National Centre for Health Statistics. Current estimates from the National Health Interview Survey, United States, 1981. Vital and Health Statistic series, 10 (141). Washington: US Government Printing Office, 1982
8. Eggenberg K. Les infections des vois respiratories les plus fréquentes chez l'enfant dans la pratique ambulatoire. Ars Medici 1993; 8: 24-30.
9. Colley JR. The vulnerable child. J R Coll Gen Pract 1975; 25 (153): 257-62.
10. Hopp R. Evaluation of recurrent respiratory tract infections in children. Curr Probl Pediatr 1996; 26 (5): 148-58.
11. Pryjma J, Kaszuba-Zwoinska J, Pawlik J, et al. Alveolar macrophages of children suffering from recurrent infections of respiratory tract are less efficient in eliminating apoptotic neutrophils. Pediatr Pulmonol 1999; 27 (3): 167-73.
12. Isaacson G. Sinusitis in childhood. Pediatr Clin North Am 1996; 43 (6): 1297-318
13. Berman S. Otitis media in children. N Engl J Med 1995; 332 (23): 1560-5.
14. Dati InfluCiri; www.influciri.it
15. Cogo R, Ramponi A, Scivoletto G, Rippoli R. Prophylaxis for acute excacerbations of chronic bronchitis using an antibacterial sublingual vaccine obtained a thruough mechanical lysis: a clinical and pharmacoeconomic study. Acta Bio Med 2003; 74: 81-7.
16. Allegra L. L'influenza e le sue complicanze. Eds Mattioli. 1885. Fidenza 2002.
17. Melioli G. La risposta immunitaria verso gli antigeni batterici è indotta in vivo da un lisato batterico ottenuto per lisi meccanica mediante un'interazione tra immunità naturale ed adattamento (acquisita). Eur Res J 2003; 22: suppl. 45.
18. Boris VM. Profilassi degli episodi di infezione delle vie aeree durante la stagione invernale con un vaccino antibatterico sublinguale ottenuto per lisi meccanica: studio clinico su pazienti affetti da pregressa malattia tubercolare. Giorn It Mal Tor 2003; 57: 210-5.
19. Boris VM, Sybirna R, Mihajlovic Gunin O. Efficacia di una terapia condotta con PMBL su di una popolazione carceraria ad alto rischio di infezioni batteriche respiratorie. Giorn It Mal Tor 2004; 58: 27-33.
20. Reynolds HY. Advances in understanding polmunary host defence mechanisms: dendritic cell function and immunomodulation. Curr Opin Pulm Med 2000; 6 (3): 209-16.
21. Rossi GA, Melioli G. Naturally occurring immune response againts bacteria commonly involved in upper respiratory tract infections: analysis of the antigen-specific salivary levels. Immunology letters 2003; 86: 85-91.
22. Rossi S, Tazza R. Valutazione delTefficacia e della tollerabilità di un nuovo vaccino immunostimolante (Ismigen®) ottenuto per lisi meccanica nella prevenzione delle patologie infettive delle basse vie respiratorie. CHEST Capitolo Italiano. Congresso nazionale Napoli 2002.
23. Rossi S, Tazza R. Valutazione delTefficacia e della tollerabilità di un nuovo vaccino immunostimolante (Ismigen®), Ottenuto per lisi meccanica, nella prevenzione delle patologie infettive delle basse vie respiratorie. American College of Chest Physicians, Italian Chapter 2002.
24. Melioli G. Opsonizzazione: mangiare o essere mangiato. Gior It Mal Tor 2002; 56: 245-8.
25. Collet JP, Ducruet T, Haider S, et al. Economic impact of using immunostimulating agent to prevent severe acute exacerbations in patients with chronic obstructive pulmonary disease. Can Respir J 2001; 8: 27-33.
26. Lydyard P, Grossi C. Cells involvement in the immune response. In: Immunology. Roit I, Brostoff J, Male D. Eds NY USA: Gowen Medical Publishing, 1990