Platelet glycoprotein Ib alpha polymorphisms affect the interaction with von Willebrand factor under flow conditions

British Journal of Haematology

Volumn 128, Issue 4, 2005, Pages 533-539

  Matsubara, Yumiko ^a   Murata, Mitsuru ^a   Hayashi, Tomohiko ^b   Suzuki, Keijiro ^c   Okamura, Yosuke ^d   Handa, Makoto ^a   Ishihara, Hiroaki ^e   Shibano, Toshiro ^e   Ikeda, Yasuo ^a  

^a KEIO UNIVERSITY   (Japan)

^b Tohoku Central Hospital   (Japan)

^c IWATE MEDICAL UNIVERSITY   (Japan)

^d WASEDA UNIVERSITY   (Japan)

^e DAIICHI SANKYO CO   (Japan)

Author keywords

Glycoprotein Ib alpha; Mutagenesis; Platelets; Polymorphisms; Von willebrand factor

Indexed keywords

ALANINE; GLYCOPROTEIN IB ALPHA; HISTIDINE; IODINE 125; METHIONINE; RECOMBINANT PROTEIN; RISTOCETIN; THREONINE; VON WILLEBRAND FACTOR;

ALLELE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTERY THROMBOSIS; ARTICLE; CELL INTERACTION; CHO CELL; CONTROLLED STUDY; DISSOCIATION CONSTANT; FLOW; GENETIC ASSOCIATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; RISK ASSESSMENT; SHEAR STRESS; TANDEM REPEAT; THROMBOGENESIS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HEMORHEOLOGY; HUMANS; MEMBRANE PROTEINS; POLYMORPHISM, GENETIC; PROTEIN BINDING; RECOMBINANT PROTEINS; RISTOCETIN; VON WILLEBRAND FACTOR;

EID: 14144253617     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2004.05349.x     Document Type: Article

References (37)

1. Afshar-Kharghan, V., Matijevic-Aleksic, N., Ahn, C., Boerwinkle, E., Wu, K.K. & Lopez, J.A. (2004) The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease. Blood, 103, 963-965.
2. Andrews, R.K., Gardiner, E.E., Shen, Y., Whisstock, J.C. & Berndt, M.C. (2003) Glycoprotein Ib-IX-V. International Journal of Biochemistry and Cell Biology, 35, 357-364.
3. Bevan, J.A., Kaley, G. & Rubanyi, G.M. (1995) Flow-Dependent Regulation of Vascular Function. Oxford University Press, Oxford.
4. Bonder, M.A., Golanski, J., Paczuski, R. & Watala, C. (2002) Polymorphisms of glycoprotein Ib affect the inhibition by aurin-tricarboxylic acid of the von Willebrand factor dependent platelet aggregation. Journal of Molecular Medicine, 80, 796-801.
5. Clemetson, K.J. (1997) Platelet GPIb-V-IX complex. Thrombosis and Haemostasis, 78, 266-270.
6. Dopheide, S.M., Yap, C.L. & Jackson, S.P. (2001) Dynamic aspects of platelet adhesion under flow. Clinical and Experimental Pharmacology and Physiology, 28, 355-363.
7. Fraker, P.J. & Speck, J.C., Jr (1978) Protein and cell membrane iodinations with a sparingly soluble chloroamide,1,3,4,6-tetrachloro-3a,6a- diphrenylglycoluril. Biochemical and Biophysical Research Communications, 80, 849-857.
8. Handa, M., Titani, K., Holland, L.Z., Roberts, J.R. & Ruggeri, Z.M. (1986) The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragments. Journal of Biological Chemistry, 261, 12579-12585.
9. Hato, T., Minamoto, Y., Fukuyama, T. & Fujita, S. (1997) Polymorphisms of HPA-1 through 6 on platelet membrane glycoprotein receptors are not a genetic risk factor for myocardial infarction in the Japanese population. American Journal of Cardiology, 80, 1222-1224.
10. Huizinga, E.G., Tsuji, S., Romijn, R.A., Schiphorst, M.E., de Groot, P.G., Sixma, J.J. & Gros, P. (2002) Structures of glycoprotein Ibalpha and its complex with von Willebrand factor Al domain. Science, 297, 1176-1179.
11. Ikeda, Y., Murata, M. & Goto, S. (1997) Von Willebrand factor-dependent shear-induced platelet aggregation: basic mechanisms and clinical implications. Annals of the New York Academy of Sciences, 811, 325-336.
12. Ikeda, Y., Handa, M., Murata, M. & Goto, S. (2000) A new approach to antiplatelet therapy: inhibitor of GPIb/V/IX-vWF interaction. Haemostasis, 30 (Suppl.), 44-52.
13. Ishida, P., Saji, H., Maruya, E. & Furihata, K. (1991) Human platelet-specific antigen, Siba, is associated with the molecular weight polymorphism of glycoprotein Ib alpha. Blood, 78, 1722-1729.
14. Ishida, P., Furihata, K., Ishida, K., Kodaira, H., Han, K.S., Liu, D.Z., Kitano, K. & Kiyosawa, K. (1996) The largest isoform of platelet membrane glycoprotein Ib alpha is commonly distributed in eastern Asian populations. Thrombosis and Haemostasis, 76, 245-247.
15. Jilma-Stohlawetz, P., Homoncik, M., Jilma, B., Knechtelsdorfer, M., Unger, P., Mannhalter, C., Santoso, S. & Panzer, S. (2003) Glycoprotein Ib polymorphisms influence platelet plug formation under high shear rates. British Journal of Haematology, 120, 652-655.
16. Kawasaki, T., Taniuchi, Y., Hisamichi, N., Fujimura, Y., Suzuki, M., Titani, K., Sakai, Y., Kaku, S., Satoh, N., Takenaka, T., Handa, M. & Sawai, Y. (1995) Tokaracetin, a new platelet antagonist that binds to platelet glycoprotein Ib and inhibits von Willebrand factor-dependent shear-induced platelet aggregation. Biochemical Journal, 308, 947-953.
17. Li, C.Q., Garner, S.F., Davies, J., Smethurst, P.A., Wardell, M.R. & Ouwehand, W.H. (2000) Threonine-145/methionine-145 variants of baculovirus produced recombinant ligand binding domain of GPIbalpha express HPA-2 epitopes and show equal binding of von Willebrand factor. Blood, 95, 205-211.
18. Lopez, J.A. (1994) The platelet glycoprotein Ib-DC complex. Blood Coagulation and Fibrinolysis, 5, 97-119.
19. Lopez, J.A., Leung, B., Reynolds, C.C., Li, C.Q. & Fox, I.E. (1992) Efficient plasma membrane expression of a functional platelet glycoprotein Ib-DC complex requires the presence of its three subunits. Journal of Biological Chemistry, 267, 12851-12859.
20. Mazzucato, M., Pradella, P., de Angelis, V., Steffan, A. & de Marco, L. (1996) Frequency and functional relevance of genetic threonine145/ methionine145 dimorphism in platelet glycoprotein Ib alpha in an Italian population. Transfusion, 36, 891-894.
21. Moriki, T., Murata, M., Kitaguchi, T., Ambo, H., Handa, M., Watanabe, K., Takahashi, H. & Ikeda, Y. (1997) Expression and functional characterization of an abnormal platelet membrane glycoprotein Ib alpha (Met239 → Val) reported in patients with platelet-type von Willebrand disease. Blood, 90, 698-705.
22. Moroi, M., Jung, S.M. & Yoshida, N. (1984) Genetic polymorphism of platelet glycoprotein Ib. Blood, 64, 622-629.
23. Murata, M., Ware, J. & Ruggeri, Z.M. (1991) Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Ib alpha demonstrating negatively charged residues involved in von Willebrand factor binding. Journal of Biological Chemistry, 266, 15474-15480.
24. Murata, M., Furihata, K., Ishida, F., Russell, S.R., Ware, J. & Ruggeri, Z.M. (1992) Genetic and structural characterization of an amino acid dimorphism in glycoprotein Ib alpha involved in platelet transfusion refractoriness. Blood, 79, 3086-3090.
25. Murata, M., Matsubara, Y., Kawano, K., Zama, T., Aoki, N., Yoshino, H., Watanabe, G., Ishikawa, K. & Ikeda, Y. (1997) Coronary artery disease and polymorphisms in a receptor mediating shear stress-dependent platelet activation. Circulation, 96, 3281-3286.
26. Nishiya, T., Murata, M., Handa, M. & Ikeda, Y. (2000) Targeting of liposomes carrying recombinant fragments of platelet membrane glycoprotein Ibalpha to immobilized von Willebrand factor under flow conditions. Biochemical and Biophysical Research Communications, 270, 755-760.
27. Ruggeri, Z.M. (2003) von Willebrand factor, platelets and endothelial cell interactions. Journal of Thrombosis and Haemostasis, 1, 1335-1342.
28. Simmonds, R.E., Hermida, J., Rezende, S.M. & Lane, D.A. (2001) Haemostatic genetic risk factors in arterial thrombosis. Thrombosis and Haemostasis, 86, 374-385.
29. Simsek, S., Bleeker, P.M., van der School, C.E. & von dem Borne, A.E. (1994) Association of a variable number of tandem repeats (VNTR) in glycoprotein Ib alpha and HPA-2 alloantigens. Thrombosis and Haemostasis, 72, 757-761.
30. Sonoda, A., Murata, M., Ito, D., Tanahashi, N., Ohta, A., Tada, Y., Takeshita, E., Yoshida, T., Saito, I., Yamamoto, M., Ikeda, Y., Fukuuchi, Y. & Watanabe, K. (2000) Association between platelet glycoprotein Ibalpha genotype and ischemic cerebrovascular disease. Stroke, 31, 493-497.
31. Suzuki, K., Hayashi, T., Akiba, J., Satoh, S. & Kato, T. (1999) Phenotypic consequence of the gene abnormality in the platelet glycoprotein IX gene observed in a patient with Bernard-Soulier syndrome through mammalian cell expression system. Thrombosis Research, 95, 295-302.
32. Titani, K., Takio, K., Handa, M. & Ruggeri, Z.M. (1987) Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Proceedings of the National Academy of Sciences of the United States of America, 84, 5610-5614.
33. Uff, S., Clemetson, J.M., Harrison, T., Clemetson, K.J. & Emsley, J. (2002) Crystal structure of the platelet glycoprotein Ib (alpha) N-terminal domain reveals an unmasking mechanism for receptor activation. Journal of Biological Chemistry, 277, 35657-35663.
34. Ulrichts, H., Vanhoorelbeke, K., Cauwenberghs, S., Vauterin, S., Kroll, H., Santoso, S. & Deckmyn, H. (2003) von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism. Arteriosclerosis, Thrombosis, and Vascular Biology, 23, 1302-1307.
35. 293 of the alpha-chain of glycoprotein Ib. Journal of Biological Chemistry, 263, 18473-18479.
36. Ware, J. (1998) Molecular analyses of the platelet glycoprotein Ib-IX-V receptor. Thrombosis and Haemostasis, 79, 466-478.
37. Yamada, Y., Izawa, H., Ichihara, S., Takatsu, F., Ishihara, H., Hirayama, H., Sone, T., Tanaka, M. & Yokota, M. (2002) Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. New England Journal of Medicine, 347, 1916-1923.