Carteolol hydrochloride protects human corneal epithelial cells from UVB-induced damage in vitro

Cornea

Volumn 24, Issue 2, 2005, Pages 213-220

  Kuwahara, Keiichi ^a   Oizumi, Nobuyuki ^a   Fujisawa, Shigeki ^a   Tanito, Masaki ^b   Ohira, Akihiro ^b  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b SHIMANE UNIVERSITY   (Japan)

Author keywords

Carteolol hydrochloride; Human corneal epithelial cells; Intraocular hypertensive drugs; Reactive oxygen species; Ultraviolet B

Indexed keywords

BETAXOLOL; CARTEOLOL; HYDROGEN PEROXIDE; LEVOBUNOLOL; NIPRADILOL; SCAVENGER; SUPEROXIDE; TIMOLOL MALEATE;

ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; CHEMOLUMINESCENCE; CONTROLLED STUDY; CORNEA EPITHELIUM; DRUG STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SPECTROPHOTOMETER; ULTRAVIOLET B RADIATION;

ANTIHYPERTENSIVE AGENTS; CARTEOLOL; CELL COUNT; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIUM, CORNEAL; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; ULTRAVIOLET RAYS;

EID: 14044280052     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ico.0000141232.41343.9d     Document Type: Article

References (22)

1. Epstein JH. Biological effect of sunlight. In: Lowe NJ, Shaath NA, eds. Sunscreens. New York: Marcel Dekker; 1990:43-54.
2. Urbach F, Gange RW, eds. The Biological Effects of UVA Radiation, New York: Praeger; 1986.
3. Taylor HR. The biological effects of UV-B on the eye. Photochem Photobiol. 1989;50:489-492.
4. Schein OD. Phototoxicity and the cornea. J Natl Med Assoc. 1992;84:579-583.
5. Roshchupkin DI, Pistsov MY, Potapenko AY. Inhibition of ultraviolet light-induced erythema by antioxidants. Arch Dermatol Res. 1979;266:91-94.
6. Miyachi Y, Horio T, Imamura S. Sunburn cell formation is prevented by scavenging oxygen intermediates. Clin Exp Dermatol. 1983;8:305-310.
7. Danno K, Horio T, Takigawa M, et al. Role of oxygen intermediates in UV-induced epidermal cell injury. J Invest Dermatol. 1984;83:166-168.
8. Sugiyama K, Enya T, Kitazawa Y. Ocular hypotensive effect of 8-hydroxycarteolol, a metabolite of carteolol. Int Ophthalmol. 1989;13:85-89.
9. Frishman WH, Fuksbrumer MS, Tannenbaum M. Topical ophthalmic beta-adrenergic blockade for the treatment of glaucoma and ocular hypertension. J Clin Pharmacol. 1994;34:795-803.
10. Tanito M, Takanashi T, Kaidzu S, et al. Cytoprotective effects of rebamipide and carteolol hydrochloride against ultraviolet B-induced corneal damage in mice. Invest Ophthalmol Vis Sci. 2003;44:2980-2985.
11. Hayashiba-Hibino S, Watanabe H, Nishida K, et al. The effect of TGF-β1 on differential gene expression profiles in human corneal epithelium studied by cDNA expression array. Invest Ophthalmol Vis Sci. 2001;42:1691-1697.
12. Ishiyama M, Shiga M, Sasamoto K, et al. A new sulfonated tetrazolium salt that produces a highly water-soluble formazan dye. Chem Pharm Bull. 1993;41:1118-1122.
13. Gotoh N, Niki E. Rate of spin trapping of superoxide as studied by chemiluminescence. Chemistry Lett. 1990;1475-1478.
14. Nakano M. Determination of superoxide radical and singlet oxygen based on chemiluminescence of luciferin analogs. Methods Enzymol. 1990;186:585-591.
15. Nishi J, Ogura R, Sugiyama M, et al. Involvement of active oxygen in lipid peroxide radical reaction of epidermal homogenate following ultraviolet light exposure. J Invest Dermatol. 1991;97:115-119.
16. Masaki H, Atsumi T, Sakurai H. Detection of hydrogen peroxide and hydroxyl radicals in murine skin fibroblasts under UVB irradiation. Biochem Biophys Res Commun. 1995;206:474-479.
17. Cejkova J, Lojda Z. Histochemical study on xanthine oxidase activity in the normal rabbit cornea and lens and after repeated irradiation of the eye with UVB rays. Acta Histochem (Jena). 1996;98:47-52.
18. Cejkova J, Stipek S, Crkovska J, et al. Changes of superoxide dismutase, catalase and glutathione peroxidase in the corneal epithelium after UVB rays. Histochemical and biochemical study. Histol Histopathol. 2000;15:1043-1050.
19. Coohill TP, Peak MJ, Peak JG. The effects of the ultraviolet wavelengths of radiation present in sunlight on human cells in vitro. Photochem Photobiol. 1987;46:1043-1050.
20. Cejkova J, Stipek S, Crkovska J, et al. Reactive oxygen species (ROS)-generating oxidases in the normal rabbit cornea and their involvement in the corneal damage evoked by UVB rays. Histol Histopathol. 2001;16:523-533.
21. Klein K. Formulating sunscreen products. In: Lowe NJ, Shaath NA, eds. Sunscreens. New York: Marcel Dekker; 1990:235-266.
22. Steenvoorden DPT, van Henegouwen GMJB. The use of endogenous antioxidants to improve photoprotection. J Photochem Photobiol B. 1997;41:1-10.