Long-term antidepressant treatment with moclobemide for aphasia in acute stroke patients: A randomised, double-blind, placebo-controlled study

Cerebrovascular Diseases

Volumn 19, Issue 2, 2005, Pages 125-132

  Laska, A C ^a   Von Arbin, M ^a   Kahan, T ^a   Hellblom, A ^a   Murray, V ^a  

^a DANDERYD HOSPITAL   (Sweden)

Author keywords

Antidepressant treatment; Aphasia; Moclobemide; Stroke

Indexed keywords

ANTIDEPRESSANT AGENT; MOCLOBEMIDE; PLACEBO;

ACUTE DISEASE; ADULT; AGED; ANOREXIA; ANXIETY; APHASIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DEPRESSION; DIARRHEA; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG INDICATION; DRUG RESPONSE; DRUG WITHDRAWAL; FATIGUE; FEMALE; FOLLOW UP; FUNCTION TEST; HEADACHE; HUMAN; INSOMNIA; LONG TERM CARE; MALE; MENTAL IRRITATION; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; STROKE; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; APHASIA; CEREBROVASCULAR ACCIDENT; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MOCLOBEMIDE; MONOAMINE OXIDASE INHIBITORS; TIME FACTORS; TREATMENT FAILURE;

EID: 14044279168     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000083256     Document Type: Article

References (23)

1. Laska AC, Hellblom A, Murray V, Kahan T, von Arbin M: Aphasia in acute stroke and relation to outcome. J Intern Med 2001;249:413-422.
2. Gladstone D, Black S: Enhancing recovery after stroke with noradrenergic pharmacotherapy: A new frontier? Can J Neurol Sci 2000;27:97-105.
3. Goldstein LB, Davis JN: Post-lesion practice and amphetamine-facilitated recovery of beam walking in the rat. Restor Neurol Neurosci 1990;1:311-314.
4. Boyeson MG, Harmon RL: Effects of trazodone and desipramine on motor recovery in brain-injured rats. Am J Phys Med Rehabil 1993;72:286-293.
5. Miyai I, Reding M: Antidepressant Effects on Recovery. New York, Futura Publishing, 1998.
6. Small S: Pharmacotherapy of aphasia. Stroke 1994;25:1282-1289.
7. Greener J, Enderby P, Whurr R: Pharmacological treatment for aphasia following stroke (Cochrane Review). The Cochrane Library Oxford: Update Software 2003.
8. Åström M, Adolfsson R, Asplund K: Major depression in stroke patients. A 3-year longitudinal study. Stroke 1993;24:976-982.
9. Fulton B, Benfield P: Moclobemide. An update of its pharmacological properties and therapeutic use. Drugs 1996;52:450-474.
10. Olsson JE, Bartfai A, Landtblom AM, Malm K, Murray V, von Arbin M, Åsberg M: Poststroke depression and moclobemide (abstract) Second World Congress of Stroke, Washington 1992.
11. World Health Organization: MONICA Project (Monitoring trends and determinants in cardiovascular disease): A major collaboration. J Clin Epidemiol 1988;41:105-114.
12. Blomert L, Kean ML, Koster C, Schokker J: Amsterdam-Nijmegen Everyday Language Test. Construction, reliability and validity. Aphasiology 1994;8:381-407.
13. World Health Organization: International Classification of Diseases. Geneva, WHO, 1986.
14. Röden-Jüllig Å, Britton M, Gustavsson C, Fugl-Meyer A: Validation of four scales for acute stage of stroke. J Intern Med 1994;236:125-136.
15. Mahoney FI, Barthel DW: Functional evaluation: Barthel Index. Md State Med J 1965;14:61-65.
16. Lingjarde O, Ahlfors UG, Bech P, Dencker SJ, Elgen K: The UKU Side Effect Rating Scale: A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr Scand 1987;76:1-80.
17. Reinvang I: Aphasia and Brain Organisation. New York, Plenum Press, 1985.
18. Kertesz A: Aphasia and Associated Disorders. New York, Grune & Stratton, 1979.
19. Enderby P, Broeckx J, Hosper W: Effect of piracetam on recovery and rehabilitation after stroke: A double-blind, placebo-controlled study. Clin Neuropharmacol 1994;17:320-331.
20. Martinsson L, Wahlgren NG, Hårdemark H-G: Amphetamine for improving recovery after stroke (Cochrane Review). The Cochrane Library Oxford: Update Software 2003.
21. Walker-Batson D, Curtis S, Natarajan R, Ford J, Dronkers N, Salmeron E, Lai J, Unwin H: A double-blind, placebo-controlled study of the use of amphetamine in the treatment of aphasia. Stroke 2001;32:2093-2098.
22. Bhogal SK, Teasell RW, Foley NC, Speechley MR: Rehabilitation of aphasia: More is better. Top Stroke Rehabil 2003;10:66-76.
23. Yuudin MBH, Weinstock M: Therapeutic application of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation. Neurotoxicology 2004;25:243-250.