Electrophysiological evidence for the presence of NR2C subunits of N-methyl-D-aspartate receptors in rat neurons of the nucleus tractus solitarius

Brazilian Journal of Medical and Biological Research

Volumn 38, Issue 1, 2005, Pages 105-110

  Baptista, V ^a   Ogawa, W N ^a   Aguiar, J F ^a   Varanda, W A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Electrophysiology; NMDA receptors; NR2C subunits; Nucleus tractus solitarius; Synapse

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT;

ANIMAL TISSUE; AREA POSTREMA; ARTICLE; BRAIN NERVE CELL; BRAIN STEM; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; ISOLATION PROCEDURE; MALE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; RAT; RECEPTOR BLOCKING; SOLITARY TRACT NUCLEUS; SYNAPTIC TRANSMISSION; TISSUE SLICE;

EID: 14044271504     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2005000100016     Document Type: Article

References (20)

1. Beckstead RM & Norgren R (1979). An autoradiographic examination of the central distribution of the trigeminal, facial, glossopharyngeal and vagal nerves in the monkey. Journal of Comparative Neurology, 184: 455-472.
2. Loewy AD (1990). Central autonomic pathway. In: Loewy AD & Spyer KM (Editors), Central Regulation of Autonomic Functions. Oxford, New York.
3. Barraco R, El-Ridi M, Ergene E, Parizon M & Bradley D (1992). An atlas of the rat subpostremal nucleus tractus solitarius. Brain Research Bulletin, 29: 703-765.
4. Grabauskas G & Bradley RM (2003). Frequency-dependent properties of inhibitory synapses in the rostral nucleus of the solitary tract. Journal of Neurophysiology, 89: 199-211.
5. Bonham AC & Chen C (2002). Glutamatergic neural transmission in the nucleus tractus solitarius: N-methyl-D-aspartate receptors. Clinical and Experimental Pharmacology and Physiology, 29: 497-502.
6. Doyle MW & Andresen MC (2001). Reliability of monosynaptic sensory transmission in brain stem neurons in vitro. Journal of Neurophysioloy, 85: 2213-2223.
7. Talman WT, Perrene MH & Reis DJ (1980). Evidence for L-glutamate as the neurotransmitter of baroreceptor afferent nerve fibers. Science, 209: 813-815.
8. Aylwin ML, Horowitz JM & Bonham AC (1997). NMDA receptors contribute to primary cisceral afferent transmission in the nucleus of the solitary tract. Journal of Neurophysiology, 77: 2539-2548.
9. Yen JW, Chan JYH & Chan SHH (1999). Differential roles of NMDA and non-NMDA receptors in synaptic responses of neurons in nucleus tractus solitarius of the rat. Journal of Neurophysiology, 81: 3034-3043.
10. Nishi M, Hinds H, Lu H, Kawata M & Hayashi Y (2001). Motoneuron specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner. Journal of Neuroscience, 21: 1-6.
11. Dingledine R, Borges K, Bowie D & Traynelis SF (1999). The glutamate receptor ion channels. Pharmacological Reviews, 51: 7-60.
12. Nowak L, Bregestovski P, Ascher P, Herbert A & Prochiantz A (1984). Magnesium gates glutamate-activated channels in mouse central neurones. Nature, 307: 462-465.
13. 2+ of NMDA responses in spinal cord neurones. Nature, 309: 261-263.
14. Anchisi D, Scelfo B & Tempia F (2001). Postsynaptic currents in deep cerebellar nuclei. Journal of Neurophysiology, 85: 323-331.
15. O'Brien JA, Isaacson JS & Berger AJ (1997). NMDA and non-NMDA receptors are co-localized at excitatory synapses of rat hypoglossal motoneurons. Neuroscience Letters, 227: 5-8.
16. Woodhull AM (1973). Ionic blockage of sodium channels in nerve. Journal of General Physiology, 61: 687-708.
17. Neher E & Steinbach JH (1978). Local anaesthetics transiently block currents through single acetylcholine-receptor channels. Journal of Physiology, 277: 153-176.
18. Acher P & Nowak L (1988). The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture. Journal of Physiology, 399: 247-266.
19. 2+ block in NMDA receptor channels. Journal of Neuroscience, 16: 3549-3558.
20. Vicini S, Wang JF, Li JH, Zhu WJ, Wang YH, Luo JH, Wolfe BB & Grayson DR (1988). Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. Journal of Neurophysiology 79: 555-566.