Cardiovascular effects of radiation therapy: Practical approach to radiation therapy-induced heart disease

Cardiology in Review

Volumn 13, Issue 2, 2005, Pages 80-86

  Lee, Peter J ^a   Mallik, Rajiv ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MICHAEL REESE HOSPITAL   (United States)

Author keywords

Chest irradiation; Pericardial effusion; Pericarditis; Radiation therapy; Radiation induced heart disease

Indexed keywords

BONE MARROW TRANSPLANTATION; CORONARY ARTERY DISEASE; HEART TAMPONADE; HUMAN; IRRADIATION; PATHOPHYSIOLOGY; PERICARDIAL EFFUSION; PERICARDITIS; RADIATION INDUCED HEART DISEASE; RADIATION INJURY; REVIEW;

CARDIOVASCULAR SYSTEM; CORONARY ARTERIOSCLEROSIS; HEART; HUMANS; RADIATION INJURIES; RADIOTHERAPY;

EID: 14044257214     PISSN: 10615377     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.crd.0000131188.41589.c5     Document Type: Review

References (59)

1. Stewart JR, Fajardo LF, Cohn KE. Experimental radiation-induced heart disease in rabbits. Radiology. 1968;91:814-817.
2. Fajardo LF, Stewart JR. Pathogenesis of radiation-induced myocardial fibrosis. Lab Invest. 1973;29:244-257.
3. Zinzani PL, Gherlinzoni F, Piovaccari G, et al. Cardiac injury as late toxicity of mediastinal radiation therapy for Hodgkin's disease patients. Haematologica. 1996;81:132-137.
4. Overgaard M, Hansen PS, Overgaard J, et al. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med. 1997;337:949-955.
5. Ragaz J, Jackson SM, Le N, et al. Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer. N Engl J Med. 1997;337:956-962.
6. Stewart JR, Fajardo LF, Gillette SM, et al. Radiation injury to heart. Int J Radiat Oncol Biol Phys. 1995;31:1205-1211.
7. Arsenian MA. Cardiovascular sequelae of therapeutic thoracic radiation. Prog Cardiovasc Dis. 1991;33:299-311.
8. Benoff LJ, Schweitzer P. Radiation therapy-induced cardiac injury. Am Heart J. 1995;129:1193-1196.
9. Fajardo LF, Stewart JR. Experimental radiation-induced heart disease. Light microscopic studies. Am J Pathol. 1970;59:299-316.
10. Veinot JP, Edwards WD. Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases. Hum Pathol. 1996;27:766-773.
11. Chello M, Mastroroberto P, Romano R, et al. Changes in the proportion of types I and III collagen in the left ventricular wall of patients with post-irradiative pericarditis. Cardiovasc Surg. 1996;4:222-226.
12. Carmel RJ, Kaplan HS. Mantle irradiation in Hodgkin's disease. An analysis of technique, tumor eradication, and complications. Cancer. 1976;37:2813-2825.
13. Jones A, Wedgwood J. Effects of radiation on the heart. Br J Radiol. 1960;33:138-158.
14. Stewart JR, Fajardo LF. Radiation induced heart disease: an update. Prog Cardiovasc Dis. 1984;27:173-194.
15. Hancock S, Donaldson S, Hoppe R. Cardiac disease following treatment of Hodgkin's disease in children and adolescents. J Clin Oncol. 1993;11:1208-1215.
16. Applefeld MM, Wiernik PH. Cardiac disease after radiation therapy for Hodgkin's disease - analysis of 48 patients. Am J Cardiol. 1983;51:1679-1681.
17. Nugue O, Millaire A, Porte H, et al. Pericardioscopy in the etiologic diagnosis of pericardial effusion in 141 consecutive patients. Circulation. 1996;94:1635-1641.
18. Thar TL, Million RR. Complications of radiation treatment of Hodgkin's disease. Semin Oncol. 1980;7:174-183.
19. Morton DL, Glancy DL, Joseph WL, et al. Management of patients with radiation-induced pericarditis with effusion: a note on the development of aortic regurgitation in two of them. Chest. 1973;64:291-297.
20. Ruckdeschel JC, Chang P, Martin RG, et al. Radiation-related pericardial effusions in patients with Hodgkin's disease. Medicine (Baltimore). 1975;54:245-259.
21. Seifert FC, Miller DC, Oesterle SN, et al. Surgical treatment of constrictive pericarditis: analysis of outcome and diagnostic error. Circulation. 1985;72:II264-II273.
22. Karram T, Rinkevitch D, Markiewicz W. Poor outcome in radiation induced constrictive pericarditis. Int J Radiat Oncol Biol Phys. 1993;25:329-331.
23. Fajardo LF. Radiation-induced coronary artery disease. Chest. 1977;71:563-564.
24. Minow RA, Benjamin RS, Lee ET, et al. Adriamycin cardiomyopathy - risk factors. Cancer. 1977;39:1397-1402.
25. Lund M, Ihlen H, Voss B, et al. Increased risk of heart valve regurgitation after mediastinal radiation for Hodgkin's disease: an echocardiographic study. Heart. 1996;75:591-595.
26. Gustavsson A, Eskilsson J, Landberg T, et al. Late cardiac effects after mantle radiotherapy in patients with Hodgkin's disease. Ann Oncol. 1990;1:355-363.
27. Boivin JF, Hutchison GB, Lubin JH, et al. Coronary artery disease mortality in patients treated for Hodgkin's disease. Cancer. 1992;69:1241-1247.
28. Hancock SL, Tucker MA, Hoppe RT. Factors affecting late mortality from heart disease after treatment of Hodgkin's disease. JAMA. 1993;270:1949-1955.
29. Glanzmann C, Huguenin P, Lutolf UM, et al. Cardiac lesions after mediastinal irradiation for Hodgkin's disease. Radiother Oncol. 1994;30:43-54.
30. Kleikamp G, Schnepper U, Körfer R. Coronary artery and aortic valve disease as a long-term sequel of mediastinal and thoracic irradiation. Thorac Cardiovasc Surg. 1997;45:27-31.
31. Drachman DE, Simon DI. Restenosis: intracoronary brachytherapy. Curr Treat Options Cardiovasc Med. 2002;4:109-118.
32. Meerkin D, Joyal M, Tardif JC, et al. Two-year angiographic follow-up of intracoronary Sr90 therapy for restenosis prevention after balloon angioplasty. Circulation. 2002;106:539-543.
33. Grise MA, Massullo V, Jani S, et al. Five-year clinical follow-up after intracoronary radiation: results of a randomized clinical trial. Circulation. 2002;105:2737-2740.
34. Chen M, Huo Y, Liu Z, et al. 192Ir endovascular irradiation prevents restenosis after balloon angioplasty in rabbit. Chin Med J (Engl). 2001;114:62-63.
35. Castagna MT, Mintz GS, Waksman R, et al. Comparative efficacy of gamma-irradiation for treatment of in-stent restenosis in saphenous vein graft versus native coronary artery in-stent restenosis: an intravascular ultrasound study. Circulation. 2001;104:3020-3022.
36. Scheinert D, Strnad V, Muller R, et al. High-dose intravascular beta-radiation after de novo stent implantation induces coronary artery spasm. Circulation. 2002;105:1420-1423.
37. Orzan F, Brusca A, Gaita F, et al. Associated cardiac lesions in patients with radiation-induced complete heart block. Int J Cardiol. 1993;39:151-156.
38. Cohen SI, Bharati S, Glass J, et al. Radiotherapy as a cause of complete atrioventricular block in Hodgkin's disease. An electrophysiological- pathological correlation. Arch Intern Med. 1981;141:676-679.
39. Bartelink H, Horiot JC, Poortmans P, et al. Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med. 2001;345:1378-1387.
40. Early Breast Cancer Trialists' Collaborative Group. Effects of radiotherapy and surgery in early breast cancer - an overview of the randomized trials. N Engl J Med. 1995;333:1444-1455.
41. Overgaard M, Christensen JJ, Johansen H, et al. Evaluation of radiotherapy in high-risk breast cancer patients: report from the Danish Breast Cancer Cooperative Group (DBCG 82) Trial. Int J Radiat Oncol Biol Phys. 1990;19:1121-1124.
42. Early Breast Cancer Trialists' Collaborative Group. Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials. Lancet. 2000;355:1757-1770.
43. Cutuli B. Cancer of the breast: results and toxicity of locoregional irradiation after mastectomy. Cancer Radiother. 2000;4(suppl 1):167s-179s.
44. Vallis KA, Pintilie M, Chong N, et al. Assessment of coronary heart disease morbidity and mortality after radiation therapy for early breast cancer. J Clin Oncol. 2002;20:1036-1042.
45. Nixon AJ, Manola J, Gelman R, et al. No long-term increase in cardiac-related mortality after breast-conserving surgery and radiation therapy using modern techniques. J Clin Oncol. 1998;16:1374-1379.
46. Hojris I, Overgaard M, Christensen JJ, et al. Morbidity and mortality of ischaemic heart disease in high-risk breast-cancer patients after adjuvant postmastectomy systemic treatment with or without radiotherapy: analysis of DBCG 82b and 82c randomised trials. Lancet. 1999;354:1425-1430.
47. Shapiro CL, Hardenbergh PH, Gelman R, et al. Cardiac effects of adjuvant doxorubicin and radiation therapy in breast cancer patients. J Clin Oncol. 1998;16:3493-3501.
48. Gyenes G, Rutqvist LE, Liedberg A, et al. Long-term cardiac morbidity and mortality in a randomized trial of pre- and postoperative radiation therapy versus surgery alone in primary breast cancer. Radiother Oncol. 1998;48:185-190.
49. Paszat LF, Mackillop WJ, Groome PA, et al. Mortality from myocardial infarction after adjuvant radiotherapy for breast cancer in the surveillance, epidemiology, and end-results cancer registries. J Clin Oncol. 1998;16:2625-2631.
50. Paszat LF, Mackillop WJ, Groome PA, et al. Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: a population-based study in Ontario, Canada. Int J Radiat Oncol Biol Phys. 1999;43:755-762.
51. Seddon B, Cook A, Gothard L, et al. Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy. Radiother Oncol. 2002;64:53-63.
52. Hardenbergh PH, Munley MT, Bentel GC, et al. Cardiac perfusion changes in patients treated for breast cancer with radiation therapy and doxorubicin: preliminary results. Int J Radiat Oncol Biol Phys. 2001;49:1023-1028.
53. Rutqvist LE, Liedberg A, Hammar N, et al. Myocardial infarction among women with early-stage breast cancer treated with conservative surgery and breast irradiation. Int J Radiat Oncol Biol Phys. 1998;40:359-363.
54. Sautter-Bihl ML, Hultenschmidt B, Melcher U, et al. Radiotherapy of internal mammary lymph nodes in breast cancer. Principle considerations on the basis of dosimetric data. Strahlenther Onkol. 2002;178:18-24.
55. Chen MH, Cash EP, Danias PG, et al. Respiratory maneuvers decrease irradiated cardiac volume in patients with left-sided breast cancer. J Cardiovasc Magn Reson. 2002;4:265-271.
56. Vaidya JS, Baum M, Tobias JS, et al. The novel technique of delivering targeted intraoperative radiotherapy (Targit) for early breast cancer. Eur J Surg Oncol. 2002;28:447-454.
57. Muren LP, Maurstad G, Hafslund R, et al. Cardiac and pulmonary doses and complication probabilities in standard and conformal tangential irradiation in conservative management of breast cancer. Radiother Oncol. 2002;62:173-183.
58. Hurkmans CW, Cho BC, Damen E, et al. Reduction of cardiac and lung complication probabilities after breast irradiation using conformal radiotherapy with or without intensity modulation. Radiother Oncol. 2002;62:163-171.
59. Storey MR, Munden R, Strom EA, et al. Coronary artery dosimetry in intact left breast irradiation. Cancer J. 2001;7:492-497.