The porcine snout - An in vitro model for human lips?

Experimental Dermatology

Volumn 14, Issue 2, 2005, Pages 96-102

  Jacobi, Ute ^a   Toll, R ^a   Audring, H ^a   Sterry, W ^a   Lademann, J ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Confocal laser scanning microscopy; Histology; Human lips; Penetration studies; Porcine snout

Indexed keywords

ANIMAL TISSUE; ARTICLE; COMPARATIVE ANATOMY; CONTROLLED STUDY; FACE; FLUORESCENCE MICROSCOPY; HISTOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LASER MICROSCOPY; LIP; NONHUMAN; SKIN BIOPSY; SKIN SURFACE; SKINFOLD THICKNESS; STRATUM CORNEUM; SWINE;

ADULT; ANIMALS; BIOPSY; DERMATOLOGY; EPIDERMIS; FEMALE; FLUORESCEIN; FLUORESCENT DYES; HUMANS; LIP; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NASAL CAVITY; SKIN; SOFTWARE; SPECIES SPECIFICITY; SWINE;

EID: 14044254859     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2005.00223.x     Document Type: Article

References (32)

1. Parry G E, Dunn P, Shah V P, Pershing L K. Acyclovir bioavailability in human skin. J Invest Dermatol 1992: 98: 856-863.
2. Volpato N M, Santi P, Laureri C, Colombo P. Assay of acyclovir in human skin layers by high-performance liquid chromatography. J Pharm Biomed Anal 1997: 16: 515-520.
3. Dubhashi S S, Vavia P R. HPTLC method to study skin permeation of acyclovir. J Pharm Biomed Anal 2000: 23: 1017-1022.
4. de Jalon E G, Blanco-Príeto M J, Ygartua P, Santoyo S. Topical application of acyclovir-loaded microparticles: quantification of the drug in porcine skin layers. J Control Release 2001: 75: 191-197.
5. Ross M H, Romrell L J, Kaye G I. Histology: A text and atlas, 3rd ed. Baltimore: Williams & Wilkins, 1995: 472-473.
6. Schuermann H. Krankheiten der Mundschleimhaut und der Lippen, 2nd ed. München, Berlin: Urban & Schwarzenberg, 1958: 5.
7. Gabard B, Ademola J. Lip sun protection factor of a lipstick sunscreen. Dermatology 2001: 203: 244-247.
8. Simon G A, Maibach H I. The pig as an experimental animal model of percutaneous permeation in man: qualitative and quantitative observations - an overview. Skin Pharmacol Appl Skin Physiol 2000: 13: 229-234.
9. Benech-Kieffer F, Wegrich P, Schwarzenbach R, et al. Percutaneous absorption of sunscreens in vitro: interspecies comparison, skin models and reproducibility aspects. Skin Pharmacol Appl Skin Physiol 2000: 13 (6): 324-335.
10. Neubert R, Wohlrab W. In vitro methods for biopharmaceutical evaluation of topical formulations. Acta Pharm Technol 1990: 36: 197-206.
11. Lademann J, Richter H, Otberg N, Lawrenz F, Blume-Peytavi U, Sterry W. Application of a dermatological laser scanning confocal microscope for investigation in skin physiology. Laser Phys 2003: 13 (5): 756-760.
12. Hatanaka T, Katayama K, Koizumi T, Sugibayashi K, Morimoto Y. Time-dependent percutaneous absorption enhancing effect of ethanol. J Control Release 1995: 33: 423-428.
13. Sznitowska M. The influence of ethanol on permeation behaviour of the porous pathway in the stratum corneum. Int J Pharmacol 1996: 137 (1): 137-140.
14. Levang A K, Zhao K, Singh J. Effect of ethanol/propylene glycol on the in vitro percutaneous absorption of aspirin, biophysical changes and macroscopic barrier properties of the skin. Int J Pharm 1999: 181 (2): 255-263.
15. Krill S L, Knutson K, Higuchi W I. Ethanol effects on the stratum corneum lipid phase behavior. Biochim Biophys Acta 1992: 112 (2): 273-280.
16. Bommannan D, Potts R O, Guy R H. Examination of the effect of ethanol on human stratum corneum in vivo using infrared spectroscopy. J Control Release 1991: 16 (3): 299-304.
17. Bouwstra J A, de Graaff A, Nijsse J, van Aelst A C. Uptake of water in the stratum corneum - the clear picture. In: Brain K R, Walters K A, eds. Perspectives in percutaneous penetration. Vol 8a. Cardiff: STS Publishing, 2002: 1.
18. Weigmann H-J, Lademann J, Meffert H, Schaefer H, Sterry W. Determination of the horny layer profile by tape stripping in combination with optical spectroscopy in the visible range as a prerequisite to quantify percutaneous absorption. Skin Pharmacol Appl Skin Physiol 1999: 12: 34-45.
19. Otberg N, Richter H, Schaefer H, Blume-Peytavi U, Sterry W, Lademann J. Variations of hair follicle size and distribution in different body sites. J Invest Dermatol 2004: 122 (1): 14-19.
20. Schaefer H, Stuttgen G, Zesch A, Schalla W, Gazith J. Quantitative determination of percutaneous absorption of radiolabeled drugs in vitro and in vivo by human skin. Curr Probl Dermatol 1978: 7: 80-94.
21. Bork K, Hoede N, Korting G W. Mundschleimhautund Lippenkrankheiten: Klinik, Differentialdiagnostik und Therapie; Atlas und Handbuch, 2nd ed. Stuttgart, New York: Schattauer, 1993: 1-2.
22. Lademann J, Otberg N, Richter H, et al. Investigation of follicular penetration of topically applied substances. Skin Pharmacol Appl Skin Physiol 2001: 14 (Suppl. 1): 17-22.
23. Genina E A, Bashkatov A N, Sinichkin Y P, et al. In vitro and in vivo study of dye diffusion into the human skin and hair follicles. J Biomed Opt 2002: 7 (3): 471-477.
24. Hostýnek J J, Dreher F, Nakada T, Schwindt D, Anigbogu A, Maibach H I. Human stratum corneum adsorption of nickel salts. Acta Derm Venereol 2001: Suppl. 212: 11-18.
25. Lauer A C, Lieb L M, Ramachandran C, Flynn G L, Weiner N D. Transfollicular drug delivery. Pharm Res 1995: 12 (2): 179-186.
26. Lauer A C, Elder J T, Weiner N D. Evaluation of the hairless rat as a model for in vivo percutaneous absorption. J Pharm Sci 1997: 86 (1): 13-18.
27. Cerio R. Histopathology of the skin: general principles. In: Champion R H, Burton J L, Burns D A, Breathnach S M, eds. Textbook of dermatology. Vol. 1, 6th ed. Oxford, London, Edinburgh: Blackwell Science, 1998: 189.
28. Stöhr P, v Möllendorff W, Goerttler K. Lehrbuch der Histologie in der mikroskopischen Anatomie des Menschen, 30th ed. Jena: VEB Gustav Fischer Verlag, 1969: 344-345.
29. Marcarian H Q, Calhoun M L. Microscopic anatomy of the integument of adult swine. Am J Vet Res 1966: 27 (118): 765-772.
30. Thibodeau E A, D'Ambrosio J A. Measurement of lip and skin pigmentation using reflectance spectrophotometry. Eur J Oral Sci 1997: 105: 373-375.
31. Toby Mathias C G, Chappler R R, Maibach H I. Contact urticaria from cinnamic aldehyde. Arch Dermatol 1980: 116: 74-76.
32. Epstein E. Treatment of lip keratoses (actinic cheilitis) with topical fluorouracil. Arch Dermatol 1977: 113: 906-908.