Chlamydia pneumoniae infection in HIV-positive patients: Prevalence and relationship with lipid profile

HIV Medicine

Volumn 6, Issue 1, 2005, Pages 27-32

  Tositti, G ^a   Rassu, M ^a   Fabris, Paolo ^a   Giordani, M T ^a   Cazzavillan, S ^a   Reatto, P ^a   Zoppelletto, M ^a   Bonoldi, M ^b   Baldo, V ^c   Manfrin, V ^a   de Lalla, F ^a  

^a SAN BORTOLO HOSPITAL   (Italy)

^b San Bartolo Hospital   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

AIDS; Chlamydia pneumoniae; Cholesterol; HDL; HIV; LDL; Triglycerides

Indexed keywords

ANTIRETROVIRUS AGENT; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHOLESTEROL; EDETIC ACID; HIGH DENSITY LIPOPROTEIN; LIPID; LOW DENSITY LIPOPROTEIN; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRIACYLGLYCEROL; VIRUS RNA;

ADULT; ARTICLE; BACTERIUM DETECTION; BLOOD SAMPLING; CARDIOVASCULAR DISEASE; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERLIPIDEMIA; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; VIRUS LOAD;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; CHLAMYDIA INFECTIONS; FEMALE; HUMANS; HYPERLIPIDEMIAS; ITALY; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PREVALENCE; RISK FACTORS; VIRAL LOAD;

EID: 13944282127     PISSN: 14642662     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2005.00261.x     Document Type: Article

References (38)

1. Kaul R, Uphoff J, Wiedeman J, Yadlapalli S, Wenman WM. Detection of Chlamydia pneumoniae DNA in CD3+ lymphocytes from healthy blood donors and patients with coronary artery disease. Circulation 2000; 102: 2341-2346.
2. Rassu M, Lauro F, Cazzavillan S et al. Detection of Chlamydophia pneumoniae DNA in peripheral blood mononuclear cells of blood donors in the north-east of Italy. Med Microbiol Immunol 2001; 190: 139-144.
3. Gnarpe J, Gnarpe H, Gause-Nilsson I, Lundorg P, Steen B. Seroprevalence of antibodies to Chlamydia pneumoniae in elderly people: a two-decade longitudinal and cohort difference study. Scand J Infect Dis 2000; 32: 177-179.
4. Campbell LA, Kuo C-C, Grayston JT. Chlamydia pneumoniae and cardiovascular disease. Emerg Infect Dis 1998; 4: 571-579.
5. Leinonen M, Saiku P. Evidence for infectious agents in cardiovascular disease and atherosclerosis. Lancet Infect Dis 2002; 2: 11-17.
6. Leinonen M. Chlamydia pneumoniae and other risk factors for atherosclerosis. J Infect Dis 2000; 181 (Suppl. 3): S414-S446.
7. Rassu M, Cazzavillan S, Scagnelli M et al. Demonstration of Chlamydia pneumoniae in atherosclerotic arteries from various vascular regions. Atherosclerosis 2001; 158: 73-79.
8. Murray LJ, O'Reilly DP, Ong GM, O'Neill C, Evans AE, Bamford KB. Chlamydia pneumoniae antibodies are associated with an atherogenic lipid profile. Heart 1999; 81: 239-244.
9. Blessing E, Campbell LA, Rosenfeld ME, Chough N, Kuo CC. Chlamydia pneumoniae infection accelerates hyperlipidemia induced atherosclerotic lesion development in C57BL/6J mice. Atherosclerosis 2001; 158: 13-17.
10. He H, Pierce G, Zhong G. The atherogenic effects of Chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae. J Clin Invest 1999; 103: 747-753.
11. Laurila A, Bloigu A, Näyhä S, Hassi J, Leinonen M, Saikku P. Chronic Chlamydia pneumoniae infection is associated with a serum lipid profile known to be a risk factor for atherosclerosis thrombosis. Arterioscler Thromb Vasc Biol 1997; 17: 2910-2913.
12. Hadigan C, Meigs JB, Corcoran C et al. Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy. Clin Infect Dis 2001; 32: 130-139.
13. Periard D, Telenti A, Sudre P et al. Atherogenic dyslipidemia in HIV-infected individuals treated with protease inhibitors. The Swiss HIV Cohort Study. Circulation 1999; 100 700-705.
14. Galli M, Ridolfo AL, Gervasoni C. Cardiovascular disease risk factors in HTV-infected patients in the HAART era. Ann N Y Acad Sci 2001; 946: 200-213.
15. Barbaro G, Fisher SD, Pellicelli AM, Lipshultz SE. The expanding role of the cardiologist in the care of HIV infected patients. Heart 2000; 86: 365-367.
16. Passalaris JD, Sepkowitz KA, Glesby MJ. Coronary artery disease and human immunodeficiency virus infection. Clin Infect Dis 2000; 31: 787-797.
17. Maggi P, Serio G, Epifani G et al. Premature lesions of the carotid vessels in HIV-I-infected patients treated with protease inhibitors. AIDS 2000; 14: F123-F128.
18. Haranaga S, Yamaguchi H, Friedman H, Izumu S, Yamamoto Y. Chlamydia pneumoniae infects and multiplies in lymphocytes in vitro. Infect Immun 2001; 69: 7753-7759.
19. Blasi F, Boman J, Esposito G et al. Chlamydia pneumoniae DNA detection in peripheral blood mononuclear cells is predictive of vascular infection. J Infec Dis 1999; 188: 2074-2076.
20. Airenne S, Surcel H-M, Alakarppa H et al. Chlamydia pneumoniae infection in human monocytes. Infect Immun 1999; 67: 1445-1449.
21. Condons R, McClune A, Rom WN, Schluger NW. Peripheral blood-based PCR assay to identity patients with active pulmonary tubercolosis. Lancet 1996; 347: 1082-1085.
22. Tong CY, Sillis M. Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR. J Clin Pathol 1993; 46: 313-317.
23. Smieja M, Mahony J, Petrich A, Boman J, Chernesky M. Association of circulating Chlamydia pneumoniae DNA with cardiovascular disease: a systematic review. BMC Infect Dis 2002; 2: 21.
24. Bodetti TJ, Timms P. Detection of Chlamydia pneumoniae DNA and antigen in the circulating mononuclear cell fractions of humans and koalas. Infect Immun 2000; 68: 2744-2747.
25. Boman J, Soderberg S, Forsberg J et al. High prevalence of Chlamydia pneumoniae DNA in peripheral blood mononuclear cells in patients with cardiovascular disease and in middle-aged blood donors. J Infect Dis 1998; 178: 274-277.
26. Apfalter P, Blasi F, Boman J et al. Multicenter comparison trial of DNA extraction methods and PCR assays for detection of Chlamydia pneumoniae in endoarterectomy specimens. J Clin Microbiol 2001; 39: 519-524.
27. Comandini UV, Maggi P, Santopadre P, Monno R, Angarano G, Vullo V. Chlamydia pneumoniae respiratory infections among patients infected with the human immunodeficiency virus. Eur J Clin Microbiol Infect Dis 1997; 16: 720-726.
28. Cosentini R, Esposito S, Blasi F et al. Incidence of Chlamydia pneumoniae infection in vertically HIV-1 infected children. Eur J Clin Microbiol Infect Dis 1998; 17: 720-723.
29. Comandini UV, Massetti AP, Marchese R, Zaccarelli M, Vullo V, Delia S. Chlamydia pneumoniae seroprevalence among HIV-1-infected and uninfected people with known HIV risk factor. AIDS 1996; 10 1543-1547.
30. Houpikian P, Raoult D. Traditional and molecular techniques for the study of emerging bacterial diseases: one laboratory perspective. Emerg Infect Dis 2002; 8: 122-131.
31. Dowell SF, Peeling RW, Boman J et al. Standardizing Chlamydia pneumoniae assays: recommendations from the Centers for Disease Control and Prevention (USA) and the Laboratory Centre for Disease Control. Clin Infect Dis 2001; 33: 492-503.
32. Halme S, Latvala J, Karttunen R, Palatsi I, Saikku P, Surcel HM. Cell-mediated immune response during primary Chlamydia pneumoniae infection. Infect Immun 2001; 68: 7156-7158.
33. Robain M, Boufassa F, Hubert JB, Persoz A, Burgard M, Meyer L. Rocho/Hemocc Study groups. Cytomegalovirus seroconversion as a cofactor for progression to AIDS. AIDS 2001; 15: 251-256.
34. Del Amo J, Malin AS, Pozniak A, De Cock KM. Does tuberculosis accelerate the progression of HIV disease? Evidence from basic science and epidemiology. AIDS 1999; 13: 1151-1158.
35. Caso G, Garlick PJ, Gelato MC, McNurlan MA. Lymphocyte protein synthesis is increased with progression of HIV-associated disease to AIDS. Clin Sci (Lond) 2001; 101: 583-589.
36. Feingold K, Grunfeld C. Role of cytokines in inducing hyperlipidemia. Diabetes 1992; 41 (Suppl. 2): 97-101.
37. Feingold KR, Hardatattir I, Memon R et al. Effect of endotoxin on cholesterol biosyntesis and distribution in serum lipoproteins in Syrian hamsters. J Lipid Res 1993; 34: 245-249.
38. Gurfinkel E, Bozovich G, Daroca A, Beck E, Mautner B. Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group. Lancet 1997; 350: 404-407.