Pancreatic exocrine insufficiency in HIV-positive patients

HIV Medicine

Volumn 6, Issue 1, 2005, Pages 33-36

  Price, David Ashley ^a   Schmid, M L ^a   Ong, E L C ^a   Adjukeiwicz, K M B ^a   Peaston, B ^b   Snow, M H ^a  

^a NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^b FREEMAN HOSPITAL   (United Kingdom)

Author keywords

Diarrhoea; Didanosine; Elastase; HIV

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; DIDANOSINE; EFAVIRENZ; ELASTASE; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; PANCREAS ENZYME; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; TENOFOVIR; ZALCITABINE; ZIDOVUDINE;

ADULT; ARTICLE; BLOATING; CHRONIC DIARRHEA; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DRUG UTILIZATION; DRUG WITHDRAWAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MEDICAL ASSESSMENT; PANCREAS FUNCTION; PANCREAS INSUFFICIENCY; PRIORITY JOURNAL; RELAPSE; RETROSPECTIVE STUDY; STEATORRHEA; SYMPTOM; TREATMENT OUTCOME; WEIGHT REDUCTION;

ADULT; ANTI-HIV AGENTS; BIOLOGICAL MARKERS; CHRONIC DISEASE; DIARRHEA; DIDANOSINE; ENZYME TESTS; EXOCRINE PANCREATIC INSUFFICIENCY; FECES; HIV INFECTIONS; HUMANS; MALE; PANCREATIC ELASTASE; PANCREATIC EXTRACTS; RETROSPECTIVE STUDIES; STEATORRHEA;

EID: 13944269960     PISSN: 14642662     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2005.00263.x     Document Type: Article

References (18)

1. Blanshard C, Francis N, Gazzard BG. Investigation of chronic diarrhoea in acquired immunodeficiency syndrome. A prospective study of 155 patients. Gut 1996; 39: 824-832.
2. Sharpstone D, Gazzard B. Gastrointestinal manifestations of HIV infection. Lancet 1996; 348: 379-393.
3. Kotler DP, Gaetz HP, Lange M, Klein EB, Holt PR. Enteropathy associated with acquired immunodeficiency syndrome. Ann Intern Med 1984; 101: 421-428.
4. Gillin JS, Shike M, Alcock N. Malabsorption and mucosal abnormalities of the small intestine in the acquired immunodeficiency syndrome. Ann Intern Med 1985; 102: 619-622.
5. Ullrich R, Zeitz M, Heise W, L'age M, Hoffken G, Riecken EO. Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): evidence for HrV-induced enteropathy. Ann Intern Med 1989; 111: 15-21.
6. Poles MA, Fuerst M, McGowan I et al. HIV-related diarrhoea is multifactorial and fat malabsorption is commonly present, independent of HAART. Am J Gastroenterol 2001; 96: 1831-1837.
7. 3. Am J Gastroenterol 2000; 95: 3142-3146.
8. Dassopoulos T, Ehrenpreis ED. Acute pancreatitis in human immunodeficiency virus-infected patients: a review. Am J Med 1999; 107: 78-84.
9. Chehter EZ, Longo MA, Laudanna AA, Duarte MI. Involvement of the pancreas in AIDS: a prospective study of 109 post-mortems. AIDS 2000; 14: 1879-1886.
10. Moore RD, Keruly JC, Chaisson RE. Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs. AIDS 2001; 15: 617-620.
11. Cappell MS, Marks M. Acute pancreatitis in HIV-seropositive patients: a case control study of 44 patients. Am J Med 1995; 98 243-248.
12. Carroccio A, Fontana M, Spagnuolo MI et al. Pancreatic dysfunction and its association with fat malabsorption in HIV infected children. Gut 1998; 43: 558-563.
13. Muench R, Ammann R. Fecal immunoreactive lipase: a new tubeless pancreatic function test. Scand J Gastroenterol 1992; 27: 289-294.
14. Loser C, Mollgaard A, Folsch UR. Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test. Gut 1996; 39: 580-586.
15. Stein J, Jung M, Sziegoleit A, Zeuzem S, Caspary WF, Lembcke B. Immunoreactive elastase I: clinical evaluation of a new noninvasive test of pancreatic function. Clin Chem 1996; 42: 222-226.
16. Dominguez-Munoz JE, Hieronymus C, Sauerbruch T, Malfertheiner P. Fecal elastase test: evaluation of a new noninvasive pancreatic function test. Am J Gastroenterol 1995; 90: 1834-1837.
17. Carroccio A, Di Prima L, Di Grigoli C et al. Exocrine pancreatic function and fat malabsorption in human immunodeficiency virus-infected patients. Scand J Gastroenterol 1999; 34: 729-734.
18. Carroccio A, Guarino A, Zuin G et al. Efficacy of oral pancreatic enzyme therapy for the treatment of fat malabsorption in HIV-infected patients. Aliment Pharmacol Ther 2001; 15: 1619-1625.