Synthesis and radiopharmacological evaluation of 2′-(4-fluorophenyl)- 21-[18F]fluoro-20-oxo-11β,17α-dihydroxy-pregn-4-eno[3,2-c] pyrazole as potential glucocorticoid receptor ligand for positron emission tomography (PET)

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 5, 2005, Pages 1303-1306

  Wüst, Frank ^a   Kniess, Torsten ^a   Kretzschmar, Marion ^a   Bergmann, Ralf ^a  

^a INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

Author keywords

Glucocorticoid receptor; Positron emission tomography; Radiolabeling

Indexed keywords

2' (4 FLUOROPHENYL) 21 FLUORO 20 OXO 11BETA,17ALPHA DIHYDROXYPREGN 4 ENO[3,2 C]PYRAZOLE F 18; GLUCOCORTICOID RECEPTOR; PYRAZOLE DERIVATIVE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN TISSUE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; IMAGING; ISOTOPE LABELING; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOCHEMISTRY; RAT; TIME; TISSUE SECTION;

RATTUS NORVEGICUS;

EID: 13944269091     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.01.033     Document Type: Article

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