Synthesis and biological activity of new 5-O-sugar modified ketolide and 2-fluoro-ketolide antibiotics

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 5, 2005, Pages 1307-1310

  Liang, Chang Hsing ^a   Yao, Sulan ^a   Chiu, Yu Hung ^a   Leung, Po Yee ^a   Robert, Nicole ^a   Seddon, Jaime ^a   Sears, Pam ^a   Hwang, Chan Kou ^a   Ichikawa, Yoshi ^a   Romero, Alex ^a  

^a Optimer Pharmaceuticals Inc   (United States)

Author keywords

2 Fluoro ketolide; Glycosylated; Ketolide; Macrolide resistance

Indexed keywords

AMINE; AZITHROMYCIN; GLUCOSE DERIVATIVE; KETOLIDE; MACROLIDE; TELITHROMYCIN; TRIAZOLE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PATHOGENESIS; RESPIRATORY SYSTEM;

EID: 13944259311     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.01.027     Document Type: Article

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