Synthesis, characterization, and structure of a new N-nitrosamine of cyclam (1,4,8,11-tetraazacyclotetradecane)

Tetrahedron Letters

Volumn 46, Issue 11, 2005, Pages 1889-1891

  Sousa, Alda Karine M H ^a   Sousa, Jackson R ^a   Santiago, Marcelo O ^a   Longhinotti, Elisane ^a   Batista, Alzir A ^b   Ellena, Javier ^c   Castellano, Eduardo E ^c   Lopes, Luiz G F ^a   Moreira, Ícaro S ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cyclam; N Nitrosamine; NO release; Photoreactivity

Indexed keywords

CYCLAM DERIVATIVE;

ARTICLE; CHEMICAL BOND; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; STRUCTURE ANALYSIS; VIBRATION; X RAY CRYSTALLOGRAPHY;

EID: 13944256265     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.01.097     Document Type: Article

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19. LCMS analyses were conducted using isocratic elution (acetonitrile/water, 90:20 v/v) with a Shimadzu C18 column (250 × 2.0 mm, 4.6 μm). The experiments were carried out on a Shimadzu LCMS-2010 equipment. The measurements were performed in positive mode by scanning between m/z 50 and 400 using an APCI interface and SIM technique