Synthesis of functionalized 1,2,3,4-tetrahydro-β-carboline derived enamines through Bischler-Napieralski type cyclization of polarized ketene N,S-acetals

Synlett

Volumn , Issue 2, 2005, Pages 309-313

  Chakrabarti, Sriparna ^a   Panda, Kausik ^a   Ila, Hiriyakkanavar ^a   Junjappa, Hiriyakkanavar ^b  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

^b BioOrganics & Applied Materials Pvt Ltd   (India)

Author keywords

carbolines; Cyclization; Enamines; Esters; Natural products; Nitriles

Indexed keywords

ACETAL; ENAMINE; ESTER; KETENE DERIVATIVE; NITRILE; TRIFLUOROACETIC ACID; TRYPTAMINE; TRYPTOLINE;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BISCHLER NAPIERALSKI REACTION; CYCLIZATION; DERIVATIZATION; POLARIZATION; REACTION ANALYSIS; STEREOISOMERISM; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 13944254377     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-836031     Document Type: Article

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63. 4) and the solvent was evaporated under reduced pressure to afford the crude product which was purified by column chromatography over silica gel using hexane-EtOAc (8:2) as eluent.