Visceral sensitivity and symptoms in patients with constipation- or diarrhea-predominant Irritable Bowel Syndrome (IBS): Effect of a low-fat intraduodenal infusion

American Journal of Gastroenterology

Volumn 100, Issue 2, 2005, Pages 383-389

  Caldarella, Maria Pia ^b   Milano, Angelo ^b   Laterza, Francesco ^b   Sacco, Flora ^b   Balatsinou, Crysanthi ^b   Lapenna, Domenico ^b   Pierdomenico, Sante Donato ^b   Cuccurullo, Franco ^b   Neri, Matteo ^a  

^a Ospedale SS Annunziata   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

LIPID; LIPID EMULSION;

ABDOMINAL PAIN; ADULT; ARTICLE; CLINICAL ARTICLE; COLON; CONSTIPATION; CONTROLLED STUDY; DIARRHEA; DIET RESTRICTION; DISEASE EXACERBATION; FEMALE; HUMAN; IRRITABLE COLON; MALE; PERCEPTION; POSTPRANDIAL STATE; PRIORITY JOURNAL; QUESTIONNAIRE; RECTUM; SYMPTOM; TENSION; DUODENUM; PATHOPHYSIOLOGY; PERCEPTIVE THRESHOLD; PRESSURE; VISCERA;

ADULT; CONSTIPATION; DIARRHEA; DUODENUM; FAT EMULSIONS, INTRAVENOUS; FEMALE; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; PERCEPTION; PRESSURE; RECTUM; SENSORY THRESHOLDS; VISCERA;

EID: 13944254073     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2005.40100.x     Document Type: Article

References (38)

1. Thompson WG, Longstreth GF, Drossman DA, et al. Functional bowel disorders and functional abdominal pain. Gut 1999;45(Suppl 2):1143-7.
2. Drossman DA, Li Z, Andruzzi E, et al. US householder survey of functional gastrointestinal disorders: Prevalence, sociodemography and health impact. Dig Dis Sci 1993;38:1569-80.
3. Hungin APS, Whorwell PJ, Tack J. The prevalence, patterns and impact of the irritable bowel syndrome: An international survey of 40,000 subjects. Aliment Pharmacol Ther 2003;17:643-50.
4. Whitehead WE, Holtkotter B, Enck P, et al. Tolerance for rectosigmoid distension in irritable bowel syndrome. Gastroenterology 1990;98:1187-92.
5. Bradette M, Delvaux M, Staumont G, et al. Evaluation of colonic sensory thresholds in IBS patients using a barostat. Definition of optimal conditions and comparison with healthy subjects. Dig Dis Sci 1994;39:449-57.
6. Lembo T, Munakata J, Mertz H. et al. Evidence for the hypersensitivity of lumbar splanchnic afferents in irritable bowel syndrome. Gastroenterology 1994;107:1686-96.
7. Lembo T, Naliboff B, Munakata J, et al. Symptoms and visceral perception in patients with pain-predominant irritable bowel syndrome. Am J Gastroenterol 1999;94:1320-6.
8. Mertz H, Naliboff B, Munakata J. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 1995;109:40-52.
9. Distrutti E, Azpiroz F, Soldevilla A, et al. Gastric wall tension determines perception of gastric distension. Gastroenterology 1999;116:1035-42.
10. Caldarella MP, Azpiroz F, Malagelada JR. Antro-fundic dysfunctions in functional dyspepsia. Gastroenterology. 2003;124:1220-9.
11. Distrutti E, Salvioli B, Azpiroz F, et al. Rectal function and bowel habit in irritable bowel syndrome. Am J Gastroenterol 2004;99:131-7.
12. Ragnarsson G, Bodemar G. Pain is temporally related to eating but not to defecation in the irritable bowel syndrome (IBS). Patients' description of diarrhea and constipation and symptom variation during a prospective 6 week study. Eur J Gastroenterol Hepatol 1998;10:415-21.
13. Accarino AM, Azpiroz F, Malagelada JR. Modification of small bowel mechanosensitivity by intestinal fat. Gut 2001;48:690-5.
14. Simren M, Abrahamsson H, Bjornsson ES. An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome. Gut 2001;48:20-7.
15. Whitehead WE, Delvaux M. Standardization of barostat procedures for testing smooth muscle tone and sensory thresholds in the gastrointestinal tract. Dig Dis Sci 1997;42:223-241.
16. Accarino AM, Azpiroz F, Malagelada JR. Modification of small bowel mechanosensitivity by intestinal fat. Gut 2001;48:690-5.
17. Accarino AM, Azpiroz F, Malagelada JR. Gut perception in human is modulated by interacting gut stimuli. Am J Physiol 2002;282:G220-5.
18. Berthoud HR, Lynn PA, Blackshaw A. Vagal and spinal mechanosensors in the rat stomach and colon could have multiple receptive fields. Am J Physiol 2001;280:R1371-81.
19. Kellow JE, Miller LJ, Phillips SF, et al. Altered sensitivity of the gallbladder to cholecystokinin octapeptide in irritable bowel syndrome. Am J Physiol 1987;253:G650-55.
20. Evans PR, Dowett JF, Bak YT, et al. Abnormal sphincter of Oddi response to cholecystokinin in postcholecystectomy syndrome patients with irritable bowel syndrome: The irritable sphincter. Dig Dis Sci 1995;40:1149-56.
21. Kellow JE, Miller LJ, Phillips SF, et al. Sensitivities of human jejunum, ileum, proximal colon, and gallbladder to cholecystokinin octapeptide. Am J Physiol 1987;252:G345-56.
22. Sabaté JM, Gorbatchef C, Flourié B, et al. Cholecystokinin octapeptide increases rectal sensitivity to pain in healthy subjects. Neurogastroenterol Motil 2002;14:689-95.
23. Ren K, Randich A, Gebhart GF. Effects of electrical stimulation of vagal afferents on spinothalamic tract cells in the rat. Pain 1991;44:311-9.
24. Melone J. Vagal receptors sensitive to lipids in the small intestine of the cat. Pain 1991;44:311-9.
25. Niebergall-Roth E, Teyssen S, Singer MV. Effects of M1 and CCK-antagonists on latency of pancreatic amylase response to intestinal stimulants. Am J Physiol 2000;279:G411-6.
26. Hammer HF, Phillips SF, Camilleri M, et al. Rectal tone, distensibility and perception: Reproducibility and response to different distensions. Am J Physiol 1998;274:G584-90.
27. Whitehead WE, Engel BT, Schuster MM. Irritable bowel syndrome: Physiological and physiological differences between diarrhea predominant and constipation predominant patients. Dig Dis Sci 1980;25:404-13.
28. Prior A, Maxton DG, Whorwell PJ. Anorectal manometry in irritable bowel syndrome differences between diarrhea and constipation predominant subjects. Gut 1990;31:458-62.
29. Ragnarsson G, Hallbook O, Bodemar G. Abdominal symptoms and anorectal function in health and irritable bowel syndrome. Scand J Gastroenterol 2001;36:833-42.
30. Talley N, Zinsmeister AR, Van Dyke C, et al. Epidemiology of colonic symptoms and irritable bowel syndrome. Gastroenterology 1991;101:927-34.
31. Talley N, Zinsmeister AR, Melton III J. Irritable bowel syndrome in a community: Symptom subgroups, risk factors, and health care utilization. Am J Epidemiol 1995;142:76-83.
32. Camilleri M. Management of the irritable bowel syndrome. Gastroenterology 2001;120:652-68.
33. Hammer J, Phillips SF, Talley NJ, et al. Effect of a 5-HT3-antagonist (ondansetron) on rectal sensitivity and compliance in health and the irritable bowel syndrome. Aliment Pharmacol Ther 1993;7:543-51.
34. Steens J, Van Der Schaar PJ, Penning C, et al. Compliance, tone and sensitivity in irritable bowel syndrome. Neurogastroenterol Motil 2002;14:241-7.
35. Kwan CL, Mikula K, Diamant NE, et al. The relationship between rectal pain, unpleasantness, and urge to defecate in normal subjects. Pain 2002;97:53-63.
36. Sabaté JM, Coffin B, Jian R, et al. Rectal sensitivity assessed by a reflexologic technique: Further evidence for two types of mechanoreceptors. Am J Physiol 2000;279:692-9.
37. Chan CLH, Facer P, Davis JB, et al. Sensory fibers expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and fecal urgency. Lancet 2003;361:385-91.
38. Lynn PA, Olsson C, Zagorodnyuk V, et al. Rectal intraganglionic laminar endings are transduction sites of extrinsic mechanoreceptors in the guinea pig rectum. Gastroenterology 2003;125:786-94.