Overdrive pacing of early ischemic ventricular tachycardia: Evidence for both reentry and triggered activity

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 288, Issue 3 57-3, 2005, Pages

  Arnar, David O ^a   Xing, Dezhi ^a   Martins, James B ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Entrainment; Ischemia; Mapping; Mechanisms

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; DOG; FEMALE; HEART HEMODYNAMICS; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART PACING; HEART VENTRICLE PACING; HEART VENTRICLE TACHYCARDIA; HEMODYNAMIC MONITORING; MALE; NONHUMAN; OVERDRIVE PACING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QRS COMPLEX; REENTRY ARRHYTHMIA; THREE DIMENSIONAL IMAGING;

ANIMALS; DOGS; FEMALE; HEART; HEART VENTRICLES; MALE; MYOCARDIAL ISCHEMIA; PACEMAKER, ARTIFICIAL; TACHYCARDIA, VENTRICULAR; VENTRICULAR FIBRILLATION;

EID: 13944250280     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01162.2003     Document Type: Article

References (23)

1. Arnar DO, Bullinga JR, and Martins JB. The role of the Purkinje system in spontaneous ventricular tachycardia during acute ischemia in a canine model. Circulation 96: 2421-2429, 1997.
2. Arnar DO, Cai JJ, Lee H, and Martins JB. Electrophysiologic effects of civamide (zucapsaicin) in canine cardiac tissue in vivo and in vitro. J Cardiovasc Pharmacol 32: 875-883, 1998.
3. Arnar DO and Martins JB. Purkinje involvement in arrhythmias after coronary artery reperfusion. Am J Physiol Heart Circ Physiol 282: H1189-H1196, 2002.
4. 2- adrenoceptors on Purkinje? Am J Physiol Heart Circ Physiol 280: H1182-H1190, 2001.
5. Ben-Haim SA, Cable DG, Rath TE, Carmen L, and Martins JB. Impulse propagation in the Purkinje system and myocardium of intact dogs. Am J Physiol Heart Circ Physiol 265: H1588-H1595, 1993.
6. Brugada J, Brugada P, Boersma L, Mont L, Kirchof C, Wellens HJJ, and Allessie MA. On the mechanism of ventricular tachycardia acceleration during programmed stimulation. Circulation 83: 1621-1629, 1991.
7. de Groot JR, Wilms-Schopman FJG, Janse MJ, and Coronel R. Reentry around slim lines of functional activation block constitutes the mechanism of 1B ventricular arrhythmias (Abstract). Pacing Clin Electrophysiol 23: 585, 2000.
8. Dillon SM, Coromilas J, Waldecker B, and Wit AL. Effects of overdrive stimulation on functional reentrant circuits causing ventricular tachycardia in the canine heart: mechanisms for resumption or alteration of tachycardia. J Cardiovasc Electrophysiol 4: 393-411, 1993.
9. Gillis AM, Leitch JW, Sheldon RS, Morillo CA, Wyse DG, Yee R, Klein GJ, and Mitchell LB. A prospective randomized comparison of autodecremental pacing to burst pacing in device therapy for chronic ventricular tachycardia secondary to coronary disease. Am J Cardiol 72: 1146-1151, 1993.
10. Ip JM, Winters SL, Schweitzer P, Lotrin A, Tepper D, and Gomes AJ. Determinants of pace-terminable ventricular tachycardia: implications for implantable antitachycardia devices. Am J Cardiol 57: 150-155, 1986.
11. Janse MJ, Capelle FJL, Morsink H, Kleber AG, Wilms-Schopman FJG, Cardinal R, Naumann d'Alnoncourt C, and Durrer D. Flow of "injury" current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts: evidence for two different arrhythmogenic mechanisms. Circ Res 47: 151-165, 1980.
12. Janse MJ, Kleber AG, Capucci A, Coronel R, and Wilms-Schopman F. Electrophysiologic basis for arrhythmias caused by acute ischemia: role of the subendocardium. J Mol Cell Cardiol 18: 339-355, 1986.
13. Josephson ME, Horowitz LE, Farshidi A, Spielman SR, Michelson EL, and Greenspan AM. Recurrent sustained ventricular tachycardia 4: pleomorphism. Circulation 59: 459-468, 1979.
14. McLean WAH, Plumb VJ, and Waldo AL. Transient entrainment and interruption of ventricular tachycardia. Pacing Clin Electrophysiol 4: 348-355, 1981.
15. Naccarelli GC, Zipes DP, Rahilly GT, Meger JJ, and Prystowsky EN. Influence of tachycardia cycle length and antiarrhythmic drugs on pacing termination and acceleration of ventricular tachycardia. Am Heart J 105: 1-5, 1983.
16. Pogwizd SM and Corr PB. Reentrant and nonreentrant mechanisms contribute to arrhythmogenesis during early myocardial ischemia: results using three-dimensional mapping. Circ Res 61: 352-371, 1987.
17. Scherlag BJ, El-Sherif N, Hope R, and Lazzara R. Characterization and localization of ventricular arrhythmias resulting from myocardial ischemia and infarction. Circ Res 35: 372-383, 1974.
18. Siebels J and Kuck KH. Effectiveness of antitachycardia pacing for ventricular tachycardia termination. In: Practical Aspects of Staged Therapy Defibrillators, edited by Klappenberger LJ and Lindemans FW. Mount Kisco, NY: Futura, 1992, p. 39-42.
19. Stevenson W, Khan H, Sager P, Saxon LA, Middlekauf HR, Natterson PD, and Wiener I. Identification of reentry sites during catheter mapping and radiofrequency ablation of ventricular tachycardia late after myocardial infarction. Circulation 88: 1647-1670, 1993.
20. Van Why K, Dexter EU, Rath T, Ben-Haim S, Iguchi A, and Martins JB. Doxorubicin prevents inducibility of ventricular tachycardia with focal origin early after coronary artery occlusion (Abstract). Pacing Clin Electrophysiol 17: 808A, 1994.
21. Waldo AL, Plumb VJ, Archiniegas JE, MacLean WAH, Cooper TB, Priesr MF, and James TN. Transient entrainment and interruption of the AV bypass type of paroxysmal atrial tachycardia. A model for understanding and identifying reentrant arrhythmias. Circulation 67: 73-79, 1983.
22. Xing D and Martins JB. Triggered activity due to delayed afterdepolarizations in sites of focal origin of ischemic ventricular tachycardia. Am J Physiol Head Circ Physiol 287: H2078-H2084, 2004.
23. Zuanetti G, Hoyt RH, and Corr PB. Beta-adrenergic-mediated influences on microscopic conduction on epicardial regions overlying infarcted myocardium. Circ Res 67: 284-302, 1990.