The halogen-lithium exchange reaction of 3,3-dichloro-2-azetidinones: Application to the synthesis of cis-4-aryl-3-chloro-2-azetidinones

Synthesis

Volumn , Issue 2, 2005, Pages 193-198

  Dejaegher, Yves ^a   Denolf, Bram ^a   Stevens, Christian V ^a   De Kimpe, Norbert ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Alkylations; Azetidinones; Lactams; Lithiation; Stereoselectivity

Indexed keywords

HALOGEN ELEMENTS; KETONES; REACTION KINETICS;

ALKYL HALIDES; ELECTROPHILES; HALOGEN-LITHIUM EXCHANGE REACTION;

SYNTHESIS (CHEMICAL);

1 BENZYL 3 CHLORO 4 PHENYL 2 AZETIDINONE; 1 BENZYL 3 CHLORO 4 PHENYL 3 PROPYL 2 AZETIDINONE; 3 CHLORO 1 CYCLOHEXYL 4 PHENYL 2 AZETIDINONE; 3 CHLORO 1 ISOPROPYL 3 METHYL 4 PHENYL 2 AZETIDINONE; 3 CHLORO 1 ISOPROPYL 4 (4 METHYLPHENYL) 2 AZETIDINONE; 3 CHLORO 1 ISOPROPYL 4 PHENYL 2 AZETIDINONE; 3 CHLORO 3 ETHYL 1 ISOPROPYL 4 PHENYL 2 AZETIDINONE; 3,3 DICHLORO 2 AZETIDINONE DERIVATIVE; AZETIDINONE DERIVATIVE; HALOGEN; LACTAM; LITHIUM; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CIS TRANS ISOMERISM; CYCLOADDITION; INFRARED SPECTROSCOPY; LITHIATION; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 13844294095     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-831248     Document Type: Article

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