Simple bromination of activated arenes by IBX amide resin and tetraethyl-ammonium bromide

Synlett

Volumn , Issue 2, 2005, Pages 279-282

  Kim, Duk Ki ^a   Chung, Woo Jae ^a   Lee, Yoon Sik ^a  

^a Seoul National University   (South Korea)

Author keywords

Bromination; IBX amide; Tetraethylammonium bromide

Indexed keywords

2 IODYLBENZOIC ACID; AMIDE; BENZALDEHYDE DERIVATIVE; BENZENE DERIVATIVE; NAPHTHALENE DERIVATIVE; NITROBENZENE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; TETRYLAMMONIUM BROMIDE; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BROMINATION; CHEMICAL REACTION KINETICS; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION KINETICS; POLYMERIZATION; PRODUCT RECOVERY; ROOM TEMPERATURE; THIN LAYER CHROMATOGRAPHY;

EID: 13844289175     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-836051     Document Type: Article

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37. 6, 25 °C): δ = 9.89 (t, 1 H, J = 6 Hz), 8.30 (d, 1 H, J = 6 Hz), 8.22 (d, 1 H, J = 6 Hz), 7.95 (t, 1 H, J = 15 Hz), 7.75 (t, 1 H, J = 15 Hz), 7.27-7.36 (m, 5 H), 4.58 (d, 2 H, J = 6 Hz).
38. 4) and evaporated. The crude product was purified by dry column chromatography to give 4-bromo-2,6-dichlorophenol (30.6 mg, yield 94%).