메뉴 건너뛰기




Volumn 10, Issue 2, 2005, Pages 115-120

Timely synthetic support for medicinal chemists

Author keywords

[No Author keywords available]

Indexed keywords

CONSULTATION; CRYSTALLIZATION; DRUG INDUSTRY; DRUG RESEARCH; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MARKET; MEDICAL INFORMATION; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; PURIFICATION; REVIEW; SCALE UP; SCREENING; SYNTHESIS;

EID: 13844271915     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(04)03298-2     Document Type: Review
Times cited : (32)

References (24)
  • 1
    • 0037861159 scopus 로고    scopus 로고
    • Lead Compounds Discovered from Libraries
    • Golebiowski A., et al. Lead Compounds Discovered from Libraries. Curr. Opin. Chem. Biol. 7:2003;308-325
    • (2003) Curr. Opin. Chem. Biol. , vol.7 , pp. 308-325
    • Golebiowski, A.1
  • 2
    • 0042330323 scopus 로고    scopus 로고
    • Increasing the Efficiency of Small-Molecule Drug Discovery
    • Bunin B.A. Increasing the Efficiency of Small-Molecule Drug Discovery. Drug Discov. Today. 8:2003;823-826
    • (2003) Drug Discov. Today , vol.8 , pp. 823-826
    • Bunin, B.A.1
  • 3
    • 0035748518 scopus 로고    scopus 로고
    • Current Practices in Generation of Small Molecule New Leads
    • Goodnow R.A. Current Practices in Generation of Small Molecule New Leads. J. Cell. Biochem. Suppl. 37:2001;13-21
    • (2001) J. Cell. Biochem. Suppl. , vol.37 , pp. 13-21
    • Goodnow, R.A.1
  • 5
    • 13844289564 scopus 로고    scopus 로고
    • Building Bridges from Process R&D: From a Customer-supplier Relationship to Full Partnership
    • Federsel H. Building Bridges from Process R&D: From a Customer-supplier Relationship to Full Partnership. Pharm. Sci. Technol. Today. 1:1998;387-393
    • (1998) Pharm. Sci. Technol. Today , vol.1 , pp. 387-393
    • Federsel, H.1
  • 6
    • 0034002261 scopus 로고    scopus 로고
    • Role of the Development Scientist in Compound Lead Selection and Optimization
    • Venkatesh S., Lipper R.A. Role of the Development Scientist in Compound Lead Selection and Optimization. J. Pharm. Sci. 89:2000;145-154
    • (2000) J. Pharm. Sci. , vol.89 , pp. 145-154
    • Venkatesh, S.1    Lipper, R.A.2
  • 7
    • 13844257853 scopus 로고    scopus 로고
    • Gearing Up for Speedy Relief
    • Lesney M.S. Gearing Up for Speedy Relief. Modern Drug Discovery. 39:2003;39-41
    • (2003) Modern Drug Discovery , vol.39 , pp. 39-41
    • Lesney, M.S.1
  • 8
    • 0034326432 scopus 로고    scopus 로고
    • Successful Implementation of Automation in Medicinal Chemistry
    • Coates W.J., et al. Successful Implementation of Automation in Medicinal Chemistry. Drug Discov. Today. 5:2000;521-527
    • (2000) Drug Discov. Today , vol.5 , pp. 521-527
    • Coates, W.J.1
  • 9
    • 0032212346 scopus 로고    scopus 로고
    • Uptake of New Technology in Lead Optimization for Drug Discovery
    • Merritt A.T. Uptake of New Technology in Lead Optimization for Drug Discovery. Drug Discov. Today. 1:1998;505-515
    • (1998) Drug Discov. Today , vol.1 , pp. 505-515
    • Merritt, A.T.1
  • 10
    • 0034193924 scopus 로고    scopus 로고
    • Current Approaches to Multiple Parallel Synthesis
    • Lawrence R.N. Current Approaches to Multiple Parallel Synthesis. Drug Discov. Today. 5:2000;172-175
    • (2000) Drug Discov. Today , vol.5 , pp. 172-175
    • Lawrence, R.N.1
  • 11
    • 0032211252 scopus 로고    scopus 로고
    • RPR's Approach to High-speed Parallel Synthesis for Lead Generation
    • Labaudiniere R.F. RPR's Approach to High-speed Parallel Synthesis for Lead Generation. Drug Discov. Today. 3:1998;511-515
    • (1998) Drug Discov. Today , vol.3 , pp. 511-515
    • Labaudiniere, R.F.1
  • 12
    • 0035358551 scopus 로고    scopus 로고
    • Techniques for Analysis and Purification in High Throughput Chemistry
    • Hughes I., Hunter D. Techniques for Analysis and Purification in High Throughput Chemistry. Curr. Opin. Chem. Biol. 5:2001;243-247
    • (2001) Curr. Opin. Chem. Biol. , vol.5 , pp. 243-247
    • Hughes, I.1    Hunter, D.2
  • 13
    • 0035165945 scopus 로고    scopus 로고
    • High-throughput Techniques for Compound Characterization and Purification
    • Kyranos J.N., et al. High-throughput Techniques for Compound Characterization and Purification. Curr. Opin. Drug Discov. Devel. 4:2001;719-728
    • (2001) Curr. Opin. Drug Discov. Devel. , vol.4 , pp. 719-728
    • Kyranos, J.N.1
  • 14
    • 0003095407 scopus 로고    scopus 로고
    • Challenges for Medicinal Chemisty
    • Wess G. Challenges for Medicinal Chemisty. Drug Discov. Today. 1:1996;529-532
    • (1996) Drug Discov. Today , vol.1 , pp. 529-532
    • Wess, G.1
  • 15
    • 0032978498 scopus 로고    scopus 로고
    • Automated Synthesis: New Tools for the Organic Chemist
    • Hird N.W. Automated Synthesis: New Tools for the Organic Chemist. Drug Discov. Today. 4:1999;265-274
    • (1999) Drug Discov. Today , vol.4 , pp. 265-274
    • Hird, N.W.1
  • 16
    • 0035523085 scopus 로고    scopus 로고
    • Z Yan, the New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery
    • Caldwell G.W., et al. Z Yan, The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery. Curr. Top. Med. Chem. 1:2001;353-366
    • (2001) Curr. Top. Med. Chem. , vol.1 , pp. 353-366
    • Caldwell, G.W.1
  • 17
    • 0041663784 scopus 로고    scopus 로고
    • st Century: Approaching the Challenges in the Pharmaceutical Industry
    • st Century: Approaching the Challenges in the Pharmaceutical Industry. Chirality. 15:2003;S128-S142
    • (2003) Chirality , vol.15
    • Federsel, H.1
  • 18
    • 0031741846 scopus 로고    scopus 로고
    • Physical Chemical Properties of Oral Drug Candidates in the Discovery and Exploratory Development Settings
    • Curatolo W. Physical Chemical Properties of Oral Drug Candidates in the Discovery and Exploratory Development Settings. Pharm. Sci. Technol. Today. 1:1998;387-393
    • (1998) Pharm. Sci. Technol. Today , vol.1 , pp. 387-393
    • Curatolo, W.1
  • 19
    • 1042298894 scopus 로고    scopus 로고
    • A Timely Re-examination of Drug Polymorphism in Pharmaceutical Development and Regulation
    • Grant D.J.W., Byrn S.R. A Timely Re-examination of Drug Polymorphism in Pharmaceutical Development and Regulation. Adv. Drug Deliv. Rev. 56:2004;237-239
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , pp. 237-239
    • Grant, D.J.W.1    Byrn, S.R.2
  • 20
    • 1042264121 scopus 로고    scopus 로고
    • Impact of Solid State Properties on Developability Assessment of Drug Candidates
    • Huang L., Tong W. Impact of Solid State Properties on Developability Assessment of Drug Candidates. Adv. Drug Deliv. Rev. 56:2004;321-334
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , pp. 321-334
    • Huang, L.1    Tong, W.2
  • 21
    • 0035341789 scopus 로고    scopus 로고
    • Drug Discoverers - You Need Us!
    • Federsel H. Drug Discoverers - You Need Us! Drug Discov. Today. 6:2001;397-398
    • (2001) Drug Discov. Today , vol.6 , pp. 397-398
    • Federsel, H.1
  • 22
    • 0037101896 scopus 로고    scopus 로고
    • The Dilemma of Process Development
    • Shultis K. The Dilemma of Process Development. Drug Discov. Today. 7:2002;850-853
    • (2002) Drug Discov. Today , vol.7 , pp. 850-853
    • Shultis, K.1
  • 23
    • 0042067947 scopus 로고    scopus 로고
    • Logistics of Process R&D: Transforming Laboratory Methods to Manufacturing Scale
    • Federsel H. Logistics of Process R&D: Transforming Laboratory Methods to Manufacturing Scale. Nat. Rev. Drug Discov. 2:2003;654-664
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 654-664
    • Federsel, H.1
  • 24
    • 0036489215 scopus 로고    scopus 로고
    • Stereoselective Synthesis from a Process Research Perspective
    • Hillier M.C., Reider P.J. Stereoselective Synthesis from a Process Research Perspective. Drug Discov. Today. 7:2002;303-314
    • (2002) Drug Discov. Today , vol.7 , pp. 303-314
    • Hillier, M.C.1    Reider, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.