Apical uptake of choline and cationic drugs in epithelial cell lines derived from human placenta

Placenta

Volumn 26, Issue 2-3, 2005, Pages 183-189

  Muller J ^a   Born, I ^a   Neubert, R H ^a   Brandsch, M ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; ATROPINE; CARBACHOL; CHOLINE; CIMETIDINE; CLONIDINE; DIPHENHYDRAMINE; ETILEFRINE; IMIPRAMINE; LIDOCAINE; METFORMIN; METHYLSCOPOLAMINE; METOPROLOL; NADOLOL; NORADRENALIN; PROCAINAMIDE; PROTON; RANITIDINE; SCOPOLAMINE; SCOPOLAMINE BUTYL BROMIDE; SODIUM ION; TETRYLAMMONIUM;

ACTIVE TRANSPORT; ARTICLE; CAPILLARY ELECTROPHORESIS; CELL CULTURE; CELL LINE; CELL TRANSPORT; CHOLINE UPTAKE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TRANSPORT; DRUG UPTAKE; EPITHELIUM CELL; HUMAN; HUMAN CELL; MATERNAL BLOOD; MICHAELIS CONSTANT; PLACENTA; PLACENTAL TRANSFER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

BIOLOGICAL TRANSPORT; CATIONS; CELL LINE, TUMOR; CHOLINE; CHORIOCARCINOMA; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; PHARMACEUTICAL PREPARATIONS; SUBSTRATE SPECIFICITY; TRITIUM; TROPHOBLASTS;

EID: 13844267765     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2004.05.001     Document Type: Article

References (31)

1. Coleman R.A. The role of the placenta in lipid metabolism and transport Semin Perinatol 13 1989 180-191
2. Zeisel S.H. Blusztajn J.K. Choline and human nutrition Annu Rev Nutr 14 1994 269-296
3. Garner S.C. Chou S.C. Mar M.H. Coleman R.A. Zeisel S.H. Characterization of choline metabolism and secretion by human placental trophoblasts in culture Biochim Biophys Acta 1168 1993 358-364
4. Saitoh H. Kobayashi M. Sugawara M. Iseki K. Miyazaki K. Carrier-mediated transport system for choline and its related quaternary ammonium compounds on rat intestinal brush-border membrane Biochim Biophys Acta 1112 1992 153-160
5. Ullrich K.J. Renal transporters for organic anions and organic cations. Structural requirements for substrates J Membr Biol 158 1997 95-107
6. +-dependent high-affinity uptake of choline into cultured fibroblasts Biochem Biophys Res Commun 30 1994 1320-1325
7. Okuda T. Haga T. Kanai Y. Endou H. Ishihara T. Katsura I. Identification and characterization of the high-affinity choline transporter Nat Neurosci 3 2000 120-125
8. Friedrich A. George R.L. Bridges C.C. Prasad P.D. Ganapathy V. Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4) Biochim Biophys Acta 1512 2001 299-307
9. Hoffmann K. Grafe F. Wohlrab W. Neubert R.H. Brandsch M. Functional characterization of a high-affinity choline transport system in human keratinocytes J Invest Dermatol 119 2002 118-121
10. Van der Aa E.M. Wouterse A.C. Peereboom-Stegeman J.H. Russel F.G. Uptake of choline into syncytial microvillus membrane vesicles of human term placenta Biochem Pharmacol 47 1994 453-456
11. Sweiry J.H. Yudilevich D.L. Characterization of choline transport at maternal and fetal interfaces of the perfused guinea-pig placenta J Physiol 366 1985 251-266
12. Eaton B.M. Sooranna S.R. Regulation of the choline transport system in superfused microcarrier cultures of BeWo cells Placenta 19 1998 663-669
13. Grassl S.M. Choline transport in human placental brush-border membrane vesicles Biochim Biophys Acta 1194 1994 203-213
14. 3H) choline in human term placenta fragments Biochem Pharmacol 25 1976 1021-1030
15. Koepsell H. Organic cation transporters in intestine, kidney, liver and brain Annu Rev Physiol 60 1998 243-266
16. Wessler I. Roth E. Deutsch C. Brockerhoff P. Bittinger F. Kirkpatrick C.J. et al. Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters Br J Pharmacol 134 2001 951-956
17. Rurak D.W. Wright M.R. Axelson J.E. Drug disposition and effects in the fetus J Dev Physiol 15 1991 33-44
18. Hohmann M. Künzel W. Etilefrine and amezinium reduce uterine blood flow of pregnant guinea pigs Eur J Obstet Gynecol Reprod Biol 30 1989 173-181
19. Yoo S.D. Axelson J.E. Taylor S.M. Rurak D.W. Placental transfer of diphenhydramine in chronically instrumented pregnant sheep J Pharm Sci 75 1986 685-687
20. Hartikainen-Sorri A.L. Heikkinen J.E. Koivisto M. Pharmacokinetics of clonidine during pregnancy and nursing Obstet Gynecol 69 1987 598-600
21. Dicke J.M. Johnson R.F. Henderson G.I. Kuehl T.J. Schenker S. A comparative evaluation of the transport of H2-receptor antagonists by the human and baboon placenta Am J Med Sci 295 1988 198-206
22. Van der Aa E.M. Wouterse A.C. Copius Peereboom-Stegeman J.H. Russel F.G. Inhibition of choline uptake in syncytial microvillus membrane vesicles of human term placenta. Specificity and nature of interaction Biochem Pharmacol 50 1995 1873-1878
23. Knütter I. Theis S. Hartrodt B. Born I. Brandsch M. Daniel H. et al. A novel inhibitor of the mammalian peptide transporter PEPT1 Biochemistry 40 2001 4454-4458
24. Burckhardt G. Pietrzyk C. The influence of an uncoupler on amino acid accumulation in Ehrlich mouse ascites tumor cells Biochim Biophys Acta 601 1980 403-414
25. Hasegawa Y. Kunihara M. Maruyama Y. Determination of picomole amounts of choline and acetylcholine in blood by gas chromatography-mass spectrometry equipped with a newly improved pyrolyzer J Chromatogr 239 1982 335-342
26. Miller A.A. Diphenhydramine toxicity in a newborn: A case report J Perinatol 20 2000 390-391
27. Zevin S. Schaner M.E. Illsley N.P. Giacomini K.M. Guanidine transport in a human choriocarcinoma cell line (JAR) Pharm Res 14 1997 401-405
28. Bzoskie L. Blount L. Kashiwai K. Tseng Y.T. Hay W.W. Jr. et al. Placental norepinephrine clearance. In vivo measurement and physiological role Am J Physiol 269 1995 E145-E149+
29. Pritchard J.B. Miller D.S. Mechanisms mediating renal secretion of organic anions and cations Physiol Rev 73 1993 765-796
30. Hayer-Zillgen M. Brüss M. Bönisch H. Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3 Br J Pharmacol 136 2002 829-836
31. Gründemann D. Liebich G. Kiefer N. Köster S. Schömig E. Selective substrates for non-neuronal monoamine transporters Mol Pharm 56 1999 1-10