Experimental acute lung injury. Effects of methylprednisolone and lidocaine on histopathology and neutrophils

Saudi Medical Journal

Volumn 25, Issue 12, 2004, Pages 1831-1834

  Sevimli, Zuhtu Utku ^a   Dogan, Nazim ^a   Kizilkaya, Mehmet ^a   Gundogdu, Cemal ^a  

^a ATATURK UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

LIDOCAINE; METHYLPREDNISOLONE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; ASPIRATION PNEUMONIA; CONTROLLED STUDY; DISEASE CONTROL; DISEASE SEVERITY; DRUG EFFICACY; HISTOPATHOLOGY; LEUKOCYTE COUNT; LUNG BIOPSY; LUNG INJURY; LUNG VENTILATION; MALE; MEDICAL SCHOOL; MONITORING; NEUTROPHIL; NONHUMAN; OXYGENATION; RABBIT; TURKEY (REPUBLIC);

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CHEMOTAXIS, LEUKOCYTE; HYDROCHLORIC ACID; LIDOCAINE; LUNG; LYMPHOCYTE COUNT; MALE; METHYLPREDNISOLONE; NEUTROPHILS; OXIDANTS; OXYGEN; PULMONARY GAS EXCHANGE; RABBITS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 13844266591     PISSN: 03795284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Britto J, Demling RH. Aspiration lung injury. New Horiz 1993;1: 435-439.
2. Sadikot RT, Christman JW. ARDS How and when does it develop? J Respir Dis 1999; 20: 348-40, 442-444.
3. Darryl YS. Respiratory Failure. In: Frederic SB, Darryl YS, editors. Critical Care Diagnosis & Treatment, 1st ed. Connecticut (USA): The McGraw-Hill Companies, Inc.; 1994. p. 37-87.
4. O'Hare B, Chin C, Lerman J, Endo J . Acute lung injury after instillation of human breast milk into rabbits' lungs. Anesthesiology 1999; 90: 1112-1118.
5. Chin C, Lerman J, Endo J. Acute lung injury after tracheal instillation of acidified soya-based or Enfalac formula or human breast milk in rabbits. Can J Anaesth 1999; 46: 282-286.
6. Nishina K, Mikawa K, Takao Y, Shiga M, Maekawa N, Obara H. Intravenous lidocaine attenuates acute lung injury induced by hydrochloric acid aspiration in rabbits. Anesthesiology 1998; 88: 1300-1309.
7. MacGregor RR, Thorner RE, Wright DM. Lidocaine inhibits granulocyte adherence and prevents granulocyte delivery to inflammatory sites. Blood 1980; 56: 203-209.
8. Kennedy TP, Johnson KJ, Kunkel RG, Ward PA, Knight PR, Finch JS. Acute acid aspiration lung injury in the rat. Biaphasic pathogenesis. Anesth Analg 1989; 69: 87-92.
9. Martling CR, Lundberg JM. Capsaicin sensitive afferents contribute to acute airway edema following tracheal instillation of hydrochloric acid or gastric juice in the rat. Anesthesiology 1988; 68: 350-356.
10. Folkesson HG, Matthay MA, Hebert CA, Broaddus VC. Acid aspiration-induced lung injury in rabbits is mediated by interieukin-8-dependent mechanism. J Clin Invest 1995; 96: 107-116.
11. Goldman G, Welbourn R, Klausner JM, Kobzig L, Valeri CR, Shepro D, Hechtman HB. Neutrophil accumulations due to pulmonary thromboxane synthesis mediate acid aspiration injury. J Appl Phys 1991; 70: 1511-1517.
12. Kjaeve J, Ingebrigtsen T, Naess L, Bjertnaes L, Vaage J. Methylprednisolone attenuates airway and vascular responses induced by reactive oxygen species in isolated, plasma-perfused rat lungs. Free Radic Res 1996; 25: 407-414.
13. Borg T, Gerdin B, Modig J. Prophylactic and delayed treatment with high-dose methylprednisolone in a porcine model of early ARDS induced by endotoxemia. Acta Anaesthesiol Scand 1985; 29: 831-845.
14. Kiyanori Y, Nishina K, Mikawa K, Maekawa N, Obara H. Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin. Crit Care Med 2000; 28: 484-489.
15. Takao Y, Mikawa K, Nishina K, Maekawa N, Obara H. Lidocaine attenuates hyperoxic lung injury in rabbits. Acta Anaesthesiol Scand 1996; 40: 318-325.
16. Mikawa K, Nishina K, Maekawa N, Takao Y, Yaku H, Obara H. Effect of lidocaine pretreatment on endotoxin-induced lung injury in rabbits. Anesthesiology 1994; 81: 689-699.
17. Chiara O, Giomarelli PP, Borelli E, Casini A, Segala M, Grossi A. Inhibition by methylprednisolone of leukocyte-induced pulmonary damage. Crit Care Med 1991; 19: 260-265.
18. Varpula T, Pettila V, Rintala E, Takkunen O, Valtonen V. Late steroid therapy in primary acute lung injury. Intensive Care Med 2000; 26: 526-531.
19. Biffl WL, Moore FA, Moore EE, Haenel JB, McIntyre RC Jr, Burch JM. Are corticosteroids salvage therapy for refractory acute respiratory distress syndrome? Am J Surg 1995; 170: 595-596.
20. Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA. Early methylprednisolone treatment for septic syndrome and adult respiratory distress syndrome. Chest 1987; 92: 1032-1036.
21. Bernard GR, Luce JM, Sprung CL, Rinaldo JE, Tate RM, Sibbald WJ et al. High-dose corticosteroids in patients with the adult respiratory distress syndrome. N Engl J Med 1987; 317: 1565-1570.