Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 288, Issue 3 51-3, 2005, Pages

  Wilkes, Jason J ^a,b,d   Nelson, Elizabeth ^a,b   Osborne, Melville ^c   Demarest, Keith T ^c   Olefsky, Jerrold M ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Whittier Institute for Diabetes   (United States)

^c JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adipose tissue; Insulin sensitization; Skeletal muscle; Zucker diabetic fatty rat

Indexed keywords

FATTY ACID; GLUCOSE; INSULIN; INSULIN SENSITIZING AGENT; TOPIRAMATE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; FATTY ACID TRANSPORT; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TRANSPORT; GLYCOGENOLYSIS; HORMONE ACTION; IN VITRO STUDY; IN VIVO STUDY; INSULIN SENSITIVITY; LIPOLYSIS; LIVER LEVEL; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; RAT; RAT STRAIN; SENSITIZATION; SOLEUS MUSCLE; WEIGHT REDUCTION;

ADIPOCYTES; ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; ANTI-OBESITY AGENTS; BLOOD GLUCOSE; BODY WEIGHT; DEOXYGLUCOSE; EATING; FATTY ACIDS, NONESTERIFIED; FEMALE; FRUCTOSE; GLUCOSE; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEPTIN; LIVER; MUSCLE, SKELETAL; OVARY; RATS; RATS, ZUCKER;

EID: 13844265654     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00437.2004     Document Type: Article

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