Apoptosis inducing effects of 6-Methoxydihydrosanguinarine in HT29 colon carcinoma cells

Archives of Pharmacal Research

Volumn 27, Issue 12, 2004, Pages 1253-1257

  Lee, Yong Jin ^a   Yin, Hu Quan ^a   Kim, Young Ho ^a,b   Li, Guang Yong ^a   Lee, Byung Hoon ^a  

^a Wonkwang University   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

6 Methoxydihydrosanguinarine; Apoptosis; HT29 cells; Hylomecon hylomeconoides

Indexed keywords

6 METHOXYDIHYDROSANGUINARINE; 6-METHOXYDIHYDROSANGUINARINE; ALKALOID; ANTINEOPLASTIC AGENT; BENZOPHENANTHRIDINE DERIVATIVE; GROWTH INHIBITOR; ISOQUINOLINE DERIVATIVE; PHENANTHRIDINE DERIVATIVE; PLANT EXTRACT;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN HT29; CHEMISTRY; COLON TUMOR; COLORECTAL TUMOR; COMPARATIVE STUDY; DRUG EFFECT; HUMAN; ISOLATION AND PURIFICATION; PATHOLOGY; PHYSIOLOGY;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZOPHENANTHRIDINES; CELL PROLIFERATION; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; GROWTH INHIBITORS; HT29 CELLS; HUMANS; ISOQUINOLINES; PHENANTHRIDINES; PLANT EXTRACTS;

EID: 13744261131     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/BF02975890     Document Type: Article

References (14)

1. Chen, J. J., Chang, Y. L., Teng, C. M., Lin, W. Y, Chen, Y. C., and Chen, I. S., A new tetrahydroprotoberberineN-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi.Plants Med., 67, 423–427 (2001). DOI: 10.1055/s-2001-15820
2. Cho, Y. S., Phytochemical constituents of Hylomecon hylomeconoides and their activities on neurotransmitter-metabolizing enzymes. Thesis: Chungnam National University (2001).
3. Devitt, G. P., Creagh, E. M., and Gotter, T. G., The antioxidant 4b, 5, 9b, 10-tetrahydroindeno[1,2-b]indole inhibits apoptosis by preventing caspase activation following mitochondrial depolarization.Biochem. Biophys. Res. Comm., 264, 622–629 (1999). DOI: 10.1006/bbrc.1999.1576
4. Giardiello, F. M., Hamilton, S. R., Krush, A. J., Piantadosi, S., Hylind, L. M., Celano, P., Booker, S. V., Robinson, C. R., and Offerhaus, G. J., Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis.N. Engl. J. Med., 328, 1313–1316 (1993). DOI: 10.1056/NEJM199305063281805
5. Greenlee, R. T., Murray, T., Bolden, S., and Wingo, P. A., Cancer statistics, 2000.CA Cancer J. Clin., 50, 7–33 (2000). DOI: 10.3322/canjclin.50.1.7
6. Herr, I. and Debatin, K. M., Cellular stress response and apoptosis in cancer therapy.Blood, 98, 2603–2614 (2001). DOI: 10.1182/blood.V98.9.2603
7. Janicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G., Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis.J. Biol. Chem., 273, 9357–9360 (1998). DOI: 10.1074/jbc.273.16.9357
8. Juo, P., Kuo, C. J., Yuan, J., and Blenis, J., Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade.Curr. Biol., 8, 1001–1008 (1998). DOI: 10.1016/S0960-9822(07)00420-4
9. Kischkel, F. C., Hellbardt, S., Behrmann, I., Germer, M., Pawlita, M., Krammer, P. H., and Peter, M. E., Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a deathinducing signaling complex (DISC) with the receptor.EMBO J., 14, 5579–5588 (1995).
10. Korsmeyer, S. J., Wei, M. C., Saito, M., Weiler, S., Oh, J., and Schlesinger, P. H., Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.Cell. Death. Differ., 7, 1166–1173 (2000). DOI: 10.1038/sj.cdd.4400783
11. Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E., p53-dependent apoptosis modulates the cytotoxicity of anticancer agents.Cell, 74, 957–967 (1993). DOI: 10.1016/0092-8674(93)90719-7
12. Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A., Gray-Goodrich, M., Campbell, H., Mayo, J., and Boyd, M., Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines.J. Natl. Cancer Inst., 83, 757–766 (1991). DOI: 10.1093/jnci/83.11.757
13. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., ORourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M., FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) deathinducing signaling complex.Cell, 85, 817–827 (1996). DOI: 10.1016/S0092-8674(00)81266-0
14. Steinbach, G., Lynch, P. M., Phillips, R. K., Wallace, M. H., Hawk, E., Gordon, G. B., Wakabayashi, N., Saunders, B., Shen, Y., Fujimura, T., Su, L. K., and Levin, B., The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis.N. Engl. J. Med., 342, 1946–1952 (2000). DOI: 10.1056/NEJM200006293422603