Extremely low penetrance of hearing loss in four Chinese families with the mitochondrial 12S rRNA A1555G mutation

Biochemical and Biophysical Research Communications

Volumn 328, Issue 4, 2005, Pages 1244-1251

  Young, Wie Yen ^a   Zhao, Lidong ^a   Qian, Yaping ^b   Wang, Qiuju ^a   Li, Ning ^c   Greinwald Jr , John H ^b   Guan, Min Xin ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

12S rRNA; A1555G; Aminoglycoside ototoxicity; Chinese; Hearing loss; Mitochondrial DNA; Modifier factor; Mutation; Nonsyndromic deafness; Nuclear background; Penetrance

Indexed keywords

ARTICLE; CHINA; CLINICAL EXAMINATION; GENE MUTATION; HAPLOTYPE; HUMAN; MITOCHONDRION; MOLECULAR GENETICS; PERCEPTION DEAFNESS; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

EID: 13744258058     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.01.085     Document Type: Article

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