Study of the antinociceptive effect of neem leaf extract and its interaction with morphine in mice [1]

Indian Journal of Pharmacology

Volumn 37, Issue 1, 2005, Pages 37-38

  Patel, J P ^a   Hemavathi, K G ^a   Bhatt, J D ^a  

^a Baroda Medical College   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINOCICEPTIVE AGENT; AZADIRACHTA INDICA EXTRACT; MORPHINE; NALOXONE; OPIATE ANTAGONIST; OPIATE RECEPTOR; SODIUM CHLORIDE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; AZADIRACHTA INDICA; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HYPERALGESIA; LETTER; MALE; MOUSE; NONHUMAN; PAIN; PLANT LEAF; STUDENT T TEST; TAIL FLICK TEST;

EID: 13744255070     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: 10.4103/0253-7613.13854     Document Type: Letter

References (5)

1. Khosla P, Bhanwra S, Singh J, Srivastava RK. Antinociceptive activity of A. Mica (Neem) in rats. Indian J Pharmacol 2000;32:372-4.
2. Barth H, Durra S, Giertz H, Goroll D, Flohe L. Long term administration of the centrally acting analgesic did not induce dependence or tolerance. Abstract No 439. Pain 1987:231.
3. D'Armour FE, Smith DL. A method for determining loss of pain sensation. J Pharmacol Exp Ther 1941;72:74-9.
4. Khanna N, Goswami M, Sen P, Ray A. Antinociceptive action of A. indica (neem) in mice: Possible mechanisms involved. Indian J Exp Biol 1995;33:848-50.
5. Witkin LB, Heubner CF, O'Keete E, Spitatalitta P, Plummer AJ. Pharmacology of 2-aminoindone hydrochloride (SU-8629): A potent non-narcotic analgesic. J Pharmacol Exp Ther 1961 ;133:400-8.